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21 April 2023 | Story Andre Damons | Photo Charl Devenish
Dr Emms
Dr Ayodeji Emmanuel Ogunbayo (right), who graduated this week with a Doctor of Philosophy degree with specialisation in Medical Virology, with his proud supervisor Prof Martin Nyaga, Associate Professor in the UFS Next Generation Sequencing (UFS-NGS).

With respiratory diseases contributing to the highest morbidity and mortality rate in children, and the vast majority of disease aetiology remaining undiagnosed in clinical settings, Dr Ayodeji Emmanuel Ogunbayo hopes his research for his PhD in Medical Virology will help to reduce mortality in children with respiratory infection.

Dr Ogunbayo, commonly known as Dr Emms by his peers, graduated on Thursday (20 April 2023) with a Doctor of Philosophy degree with specialisation in Medical Virology at the University of the Free State (UFS) Faculty of Health Sciences graduation ceremony. The title of his thesis was Metagenomics of the respiratory RNA virome of children in the Free State. His supervisor was Prof Martin Nyaga, Associate Professor in the UFS Next Generation Sequencing (UFS-NGS) and Director of the WHO Collaborating Centre (WHO CC).

“While clinical metagenomics next-generation sequencing (mNGS), which is an upcoming method, has the potential to revolutionise infection diagnosis and management in children, there is a dearth of information on its clinical applicability in Africa. This is the knowledge that guided the inception of this research,” says Dr Ogunbayo.

Project came at the right time

He commenced with his PhD in Medical Virology in 2019, which was centred on the applicability of mNGS in severe acute respiratory infection (SARI) in children and deciphering the children’s respiratory virome in health and disease, a project which was the first of its kind in Africa.

According to him, the project was conceived before the COVID-19 pandemic, however, despite the challenges encountered due to lockdown measures, the project came at the right time as it was able to address several profound effects of the pandemic such as COVID-19 on the dynamics of transmission of respiratory viruses and ultimately its effect on children’s health. During his PhD study, he published four manuscripts in highly reputable journals including the most recent one which was accepted in Journal of Medical Virology (JMV)  an impressive impact factor of 20.693.

The findings from this study included a validated and robust workflow to recover respiratory RNA viruses from clinical samples, according to the graduation programme. The established workflow was adapted to decipher children’s respiratory virome composition in health and disease, with a degree of heterogeneity, while simultaneously establishing the clinical diagnostic applicability of mNGS and, more importantly, the increased utility of dual-triple mNGS analysis tools in robust detection of viral pathogens in SARI.

His hope for the research

Dr Ogunbayo says: “This research generated vast pioneering information and data in Africa that could guide and influence policy in the adoption of clinical metagenomics, especially in cases where conventional methods of diagnosis yielded no results. Hopefully, this could lessen mortality due to respiratory infection in children.

Before studying in the field of medical Microbiology and Virology, he wanted to be a psychiatric nurse, but instead chose his current field of study because of his interest in the microbial world and pathology.

“It’s a feeling one cannot really put into words. A part of me feels like it is a ‘dream come true’ and another part of me feels like ‘this is a milestone achieved, but it’s just a stepping stone to further milestones to be achieved’.

“What is next is for me to dive into the world of policy-influencing research, give back to the academic community through student supervision, and work on my journey to becoming an emerging researcher. This is the reason I have taken a postdoctoral position at the UFS-NGS Unit under the mentorship of Prof Martin Nyaga.”

Prof Nyaga says: “Looking back at Emmanuel’s doctoral journey, it brought out the best in him in every aspect of the study. Longitudinal studies are hectic in the sampling phase, and all the ethical clearances that a study must achieve prior to beginning the sampling and the laboratory work can be very frustrating. Soon after his study was approved, the pandemic lockdown level 5 rules were applied, which meant he had to pause on the study. However, his focus, positive mindset and his ability to work in close consultation with his supervisor enabled him to finish this study in the best way possible. I am very proud of him.”

News Archive

UFS to accredit providers of Off-Campus Accommodation to students in Bloemfontein
2017-06-30

The University of the Free State (UFS) has embarked on a process to accredit off-campus accommodation service providers in Bloemfontein who provide accommodation to its students.

“The decision to accredit off-campus accommodation service providers comes from a concern from the university management about the safety of students and the conditions under which some of our students live in off-campus accommodation. Student accommodation is a significant aspect of the success of the UFS and consequently good quality accommodation is important for each individual student to be successful in his/her studies,” says Mr Quintin Koetaan, Senior Director: Housing and Residence Affairs at the UFS.

The accreditation process entails a list of primary requirements, drafted with the cognisance of the Mangaung Metropolitan Municipality, in terms of off-campus accommodation to which private providers must adhere in order to be accredited by the university. The requirements are in line with the Policy on the Minimum Norms and Standards for Student Housing at Public Universities (Government Gazette 39238, dated 29 September 2015).

According to Koetaan, the norms and standards as set out in the policy establish the foundation and assessment criteria for such accreditation of service providers by the UFS. “It has become necessary for the UFS to have a policy on off-campus accommodation, in order to protect the rights and interests of our students and that of the university,” says Koetaan.

Some of the primary requirements for accreditation by the UFS include the number of students that may be accommodated in each room, the quality of kitchens and kitchenettes, the number of ablution facilities, the existence of common rooms and house rules, general maintenance and cleaning, compliance with  relevant national, regional, and municipal legislative requirements regulating health and safety, provision for adequate access to the facility/establishment in case of medical and/or psychological emergency assistance being required by students, and the provision for access to emergency electricity and water facilities. Off-campus private accommodation service providers must also be in possession of approved Municipal building plans of their student accommodation facilities, as well as evidence confirming their compliance with these plans.

“Landlords and agents are also advised to become more involved in their student homes and to ensure that their properties are in good condition and secure enough for students to live in,” says Koetaan.

Off-campus private accommodation service providers have until 31 July 2017 to apply for accreditation. More information and application documentation for accreditation can be obtained by sending an email to housing@ufs.ac.za

Released by:
Lacea Loader (Director: Communication and Brand Management)
Telephone: +27 51 401 2584 | +27 83 645 2454
Email: news@ufs.ac.za | loaderl@ufs.ac.za
Fax: +27 51 444 6393

 

 

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