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13 July 2023 | Story André Damons | Photo André Damons
Tebogo Machete
Tebogo Machethe has recently been appointed Director for Innovation and Contracts in the Directorate of Research Development (DRD) at the University of the Free State (UFS).

The recently appointed Director for Innovation and Contracts in the Directorate of Research Development (DRD) at the University of the Free State (UFS) would like to see the university’s research outcome being adopted by industry and research output translating into commercial opportunities and more income.

Tebogo Machethe, who is experienced in managing intellectual property and commercialising technologies, amongst other things, assumed his new role on 1 June and has felt right at home. He is looking forward to a good working relationship and environment with all the stakeholders. 

“I would also like to see a huge drive wherein the commercialisation activities and income of the university from commercialisation of Intellectual Property (IP) increases from the research been undertaken. We will also be intensifying the entrepreneurial drive at the university with a view to creating more entrepreneurship opportunities and skills for researchers and students. This will prepare our graduates to venture into entrepreneurship once they are done with their studies,” says Machethe.

According to him, South Africa now needs research that responds to the needs of society and provides solutions to society’s problems.  

Intellectual property, commercialising technologies, contracts 

Before joining the UFS, Machethe had been a Senior Manager: Technology Transfer at the University of Johannesburg for the past six years. He also spent some time at CIPRO (currently known as Companies and Intellectual Property Commission (CIPC) from 2004-2006 before joining Hahn & Hahn Inc as a Candidate patent attorney until late 2008. He then moved to the Council for Scientific and Industrial Research (CSIR): Materials Science and Manufacturing business unit in the Intellectual Property & Technology Transfer office. 

“Most of my duties revolved around managing intellectual property, commercialising technologies and drafting and managing contracts only related to IP and Technology Transfer. My current duties have expanded to all forms of contracts and also involvement in grant funding and other forms of funding,” says Machethe.

He says as a research office, the DRD exists in an eco-system wherein there are different role players. Through different role players, there is always a convergence of thinking and approaches which when all put together, puts the institution on a path to achieve the goals of the university.

Fun facts about Tebogo Machethe

  • He grew up in a small village called Ga-Raphahlelo, in Sekgosese, Mopani district, Limpopo. He is married with three children. 
  • When he is not pre-occupied with office matters, he tries to spend as much time with his family. He loves reading, running and cycling, which he often does.
  • He has lived for the last two decades in Pretoria and is finding the Free State winter challenging. “It feels personal,” he says. 

News Archive

UFS cardiac team leading with project
2017-05-31

 Description: Cardiac team read more Tags: Cardiac team read more

Prof Peter Schultheiss of the Charité University in Berlin,
Germany, visited the Robert WM Frater Centre for
Cardiovascular Research at the UFS for a study regarding
cardiomyopathy, a significant cause of fatal heart failure
among Africans. From the left are Dr Glen Taylor,
Dr Danie Buys, Prof Makoali Makatoko,
Prof Schultheiss and Prof Francis Smit.
Photo: Rulanzen Martin

A team of cardiac doctors associated with the Robert WM Frater Cardiovascular Research Centre at the University of the Free State’s (UFS) Faculty of Health Sciences has commenced with a pioneering research project regarding idiopathic dilating cardiomyopathy.  

An Afrocentric research focus
Prof Francis Smit, Head of the Department of Cardiothoracic Surgery at the UFS and Head of the Frater Centre, describes dilating cardiomyopathy as a heart muscle disease that is quite common, particularly among people of African descent. The disease weakens the heart muscle, which in turn leads to heart failure.

“To date there is no curable treatment for this condition and 50% of patients that have shown heart failure, died within a period of five years. The causes of this condition have been unknown in the majority of patients. But over the past few years major strides have been made where virus infections of the heart muscle or myocarditis have been identified as a possible underlying cause. Various genetic diseases are also linked to it,” says Prof Smit.

International collaborations ensure success
According to Prof Smit, the project is being run in conjunction with Prof Heinz-Peter Schultheiss of the Charité University and the Institute for Cardiac Diagnostics and Therapy in Berlin, Germany.

“We have been working on the project over the past 18 months and I have twice visited Prof Schultheiss in Germany. He is now visiting us in Bloemfontein. We have established a collaborative project focused on patients in central South Africa”.
Prof Schultheiss is a world leader regarding the diagnosis, pathology and treatment of dilating cardiomyopathy, says Prof Smit.

“He brings a lifetime of research experience to Bloemfontein and is internationally renowned as the father of myocardial or heart muscle biopsies.

“His pioneering work on the discipline has led to diagnostic accuracy that has induced purposeful and personalised treatment of dilating cardiomyopathy and has brought about dramatic changes in some subsets of patients’ life expectancy and their cure.”

Solving problems close to home
According to Prof Mokoali Makatoko, Head of the Department of Cardiology, there are more than 1500 new cases of heart failure identified annually at the Universitas Academic Hospital, of which approximately 30% are attributed to cardiomyopathy. “With the use of endomyocardial biopsies the team hopes to treat viruses unique to Southern Africa as well as other underlying causes of dilating cardiomyopathy.”

Prof Stephen Brown, Head of Paediatric Cardiology at the Universitas Academic Hospital, says children suffering from this disease never reach a mature age and those under his supervision will also be undergoing these tests. Various other departments at the UFS will also participate in this project. Profs Makatoko and Brown did the first four endomyocardial biopsies under the management of Prof Schultheiss during the past week. The results will be available in the coming weeks after which the project will be officially launched and patient recruitment will start in earnest.

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