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24 May 2023 | Story André Damons | Photo André Damons
Prof Motlalepula Matsabisa

The African Medicines Innovations and Technologies Development Platform (AMITD) within the Department of Pharmacology at the University of the Free State (UFS) hosted a delegation from the Chinese Embassy in Pretoria, led by the Minister-Counsellor of the People’s Republic of China. The aim of the visit was to cement the collaborative relationship between UFS Indigenous Knowledge System (IKS) and the Beijing University of Chinese Medicines (BUCM).

The visit of the Minister-Counsellor, Mr Shen Long, and his staff in Science and Technology on Friday (19 May 2023) was also to gain support for the application for two projects between the UFS and BUCM, said Prof Motlalepula Matsabisa, Director of Pharmacology at the UFS and Head of AMITD.

“First is the innovation project that we are spearheading in order to be recognised as a Presidential project, the signing of which will be witnessed by both the presidents of South Africa and China during the BRICS Summit in August.”

“The second project is that of the UFS driving the establishment of the BRICS Natural Medicines Institute, supported by the Department of Science and Innovation (DSI), the National Department of Health (DoH), and the Department of International Relations and Cooperation (DIRCO). The UFS has been earmarked to head this institute.  All the BRICS countries’ scientists support the UFS’ idea of a BRICS Natural Medicines Institute,” said Prof Matsabisa.

The UFS Pharmacology IKS also made a presentation during a virtual meeting with the natural products scientists in the BRICS countries for support and adoption of the concept on the BRICS Natural Medicines Institute.

The Chinese delegation also got to tour FARMOVS and the new AMITD laboratories.

Collaboration and co-creation

Prof Francis Petersen, Rector and Vice-Chancellor of the UFS, said he would like to see how the relationship between the UFS and BUCM can be strengthened and how it can be fed into the China-South Africa bilateral.

According to him, the university is open to supporting such initiatives, and hopefully this indigenous knowledge hub can become a critical focal point within such a potential institute under BRICS.

“It is important to see how different contexts play out in research and development. Collaboration and the whole aspect of co-creation is quite important, and I think there is a good relationship between the UFS and the BUCM that started some years ago; this is a good illustration of how important collaboration is.” He further wished to see the collaboration between BUCM and the UFS go beyond IKS to other aspects of research, health, and teaching.

The basis of the relationship between BUCM and the UFS, specifically in the Department of Pharmacology and this IKS group, is built on collaboration and co-creation. The question now, according to Prof Petersen, is how to expand and strengthen that relationship. He said that without any support from funding agencies, governments, and support through structured programmes such as bilateral agreements, this programme and collaboration engagement would not be possible.

BUCM and UFS can play important role in traditional medicine

Mr Shen said several collaboration projects already exist between China and South Africa in the area of science and technology. He said: “We also want to promote collaboration between the two sides in the area of biotechnology, including agricultural, medical, as well as traditional. We also promote collaboration on traditional medicine; in China, our traditional medicine has helped to fight the COVID-19 pandemic. Here in South Africa, you are only starting with traditional African medicine. You want to develop your own standards, while in China we have already developed teaching about this, so we would like to cooperate in this area. You can learn a lot from China, and we can learn from South Africa as well.”

According to him, China can help South Africa collaborate with partners to develop its own traditional medicine and the whole value chain in traditional medicine, from the medical plants to clinical trials to manufacturing. “BUCM and the UFS can play a very important role in this particular area.”

Prof Xu Anlong, President of BUCM, pledged his support for this collaboration between the two institutions via Zoom. He said he hoped it would be successful and fruitful and hopefully they can train some of the UFS students at BUCM.

UFS to host BRICS institute

Prof Matsabisa, who was previously awarded a Visiting Professorship at BUCM in Beijing, China, further said he hoped the collaboration can be strengthened and expanded to other disciplines in terms of research and health.

“The complete value chain of traditional medicine and medicinal plant development is something of interest to us, especially the UFS, because we are going down that route. The UFS has been asked by the DST and the South African Health Products Regulatory Authority (SAHPRA) to lead a team of experts to assist and advise government on how we can contribute to the amendment of the Medicines Act and how we can propose a regulatory framework for traditional medicine products for SAHPRA to regulate.”

“This is something that has been driven by the UFS in the context of developing South African traditional medicines – developing all value chains to include commercialisation. This also means medium- to long-term development of curricula that will pave the way for the integrated health system in South Africa.”

Prof Matsabisa is already thinking of a pilot programme for integrated health facilities or clinics, where medical doctors and trained traditional health practitioners could work side by side in the same facilities and attend to the same patients. He will also convene two meetings of BRICS scientists as part of a proposed BRICS Institute for Training, Research and Innovation in Natural Medicines hosted by the UFS.

The Minister-Counsellor, Mr Shen Long, during his visit to the Bloemfontein Campus of the University of the Free State (UFS).
The Minister-Counsellor, Mr Shen Long, during his visit to the Bloemfontein Campus of the University of the Free State (UFS).
Mr Shen Long, Minister-Counsellor of the Science and Technology Section at the Chinese Embassy (left), Dr Li Yan, First Secretary of the Science and Technology Section (right), and Dr Pan Xu, Second Secretary of the Science and Technology Section during t
Mr Shen Long, Minister-Counsellor of the Science and Technology Section at the Chinese Embassy (left), Dr Li Yan, First Secretary of the Science and Technology Section (right), and Dr Pan Xu, Second Secretary of the Science and Technology Section during t
Recardia Schoeman, Science Officer in the Department of Pharmacology, showing Mr Shen Long, Minister-Counsellor of the Science and Technology Section at the Chinese Embassy (middle), Dr Li Yan, First Secretary of the Science and Technology Section (right
Recardia Schoeman, Science Officer in the Department of Pharmacology, showing Mr Shen Long, Minister-Counsellor of the Science and Technology Section at the Chinese Embassy (middle), Dr Li Yan, First Secretary of the Science and Technology Section (right
Prof Francis Petersen, Rector and Vice-Chancellor of the UFS, was part of the discussion between the representatives of the Chinese Embassy in South Africa and the University of the Free State (UFS).
Prof Francis Petersen, Rector and Vice-Chancellor of the UFS, was part of the discussion between the representatives of the Chinese Embassy in South Africa and the University of the Free State (UFS).
Mr Shen Long, Minister-Counsellor of the Science and Technology Section at the Chinese Embassy (in the middle), Dr Li Yan, First Secretary of the Science and Technology Section (2nd from the left), and Dr Pan Xu, Second Secretary of the Science and Techno
Mr Shen Long, Minister-Counsellor of the Science and Technology Section at the Chinese Embassy (in the middle), Dr Li Yan, First Secretary of the Science and Technology Section (2nd from the left), and Dr Pan Xu, Second Secretary of the Science and Techno
Mr Shen Long, Minister-Counsellor of the Science and Technology Section at the Chinese Embassy (2nd from left), Dr Li Yan, First Secretary of the Science and Technology Section (2nd from the right), and Dr Pan Xu, Second Secretary of the Science and Techn
Mr Shen Long, Minister-Counsellor of the Science and Technology Section at the Chinese Embassy (2nd from left), Dr Li Yan, First Secretary of the Science and Technology Section (2nd from the right), and Dr Pan Xu, Second Secretary of the Science and Techn

News Archive

Champagne and cancer have more in common than you might think
2013-05-08

 

Photo: Supplied
08 May 2013

No, a glass of champagne will not cure cancer....

…But they have more in common than you might think.

Researchers from the Departments of Microbial Biochemical and Food Biotechnology, Physics and the Centre for Microscopy at the University of the Free State in South Africa were recently exploring the properties of yeast cells in wine and food to find out more of how yeast was able to manufacture the gas that caused bread to rise, champagne to fizz and traditional beer to foam. And the discovery they made is a breakthrough that may have enormous implications for the treatment of diseases in humans.

The team discovered that they could slice open cells with argon gas particles, and look inside. They were surprised to find a maze of tiny passages like gas chambers that allowed each cell to ‘breathe.’ It is this tiny set of ‘lungs’ that puts the bubbles in your bubbly and the bounce in your bread.

But it was the technique that the researchers used to open up the cells that caught the attention of the scientists at the Mayo Clinic (Tumor Angiogenesis and Vascular Biology Research Centre) in the US.

Using this technology, they ultimately aim to peer inside cells taken from a cancer patient to see how treatment was progressing. In this way they would be able to assist the Mayo team to target treatments more effectively, reduce dosages in order to make treatment gentler on the patient, and have an accurate view of how the cancer was being eliminated.

“Yes, we are working with the Mayo Clinic,” said Profes Lodewyk Kock from the Microbial, Biochemical and Food Biotechnology Department at the UFS.

“This technique we developed has enormous potential for cell research, whether it is for cancer treatment or any other investigation into the working of cells. Through nanotechnology, and our own invention called Auger-architectomics, we are able to see where no-one has been able to see before.”

The team of Prof Kock including Dr Chantel Swart, Kumisho Dithebe, Prof Hendrik Swart (Physics, UFS) and Prof Pieter van Wyk (Centre for Microscopy, UFS) unlocked the ‘missing link’ that explains the existence of bubbles inside yeasts, and incidentally have created a possible technique for tracking drug and chemotherapy treatment in human cells.

Their work has been published recently in FEMS Yeast Research, the leading international journal on yeast research. In addition, their discovery has been selected for display on the cover page of all 2013 issues of this journal.

One can most certainly raise a glass of champagne to celebrate that!

There are links for video lectures on the technique used and findings on the Internet at:

1. http://vimeo.com/63643628 (Comic version for school kids)

2. http://vimeo.com/61521401 (Detailed version for fellow scientists)

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