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04 October 2023 | Story Prof Robert Bragg | Photo Supplied
Prof Robert Bragg
Prof Robert Bragg is from the Veterinary Biotechnology in the Department of Microbiology and Biochemistry, University of the Free State (UFS).

Opinion article by Prof Robert Bragg, Veterinary Biotechnology in the Department of Microbiology and Biochemistry, University of the Free State.


The poultry sector in South Africa is currently undergoing serious challenges. 

The ongoing load shedding and power disruptions have put tremendous pressure and additional costs on the industry, which makes producing poultry products extremely expensive. One company (Astral Foods) has spent an additional R919 million as a result of load shedding alone. This has obviously had a significant impact on the profitability and sustainability of the company.

Now to make matters worse – the local poultry industry has been hit with a major avian influenza epidemic.

Avian Influenza (AI) is a viral disease of birds, including poultry. The term “AI” is frequently in the news these days and often refers to artificial intelligence. In this article, the term AI refers to Avian Influenza. This is a devastating disease of poultry and can wipe out a flock in just a few days. AI is the most widely-studied disease of poultry as it has been causing major problems in poultry industries around the world for many years.

Reluctance to vaccinate 

In the past (five to 10 years ago) Avian influenza (AI), was pretty much the only serious poultry disease which South Africa did not have. There have been cases of what is called low pathogenic Avian Influenza in ostriches for some time. However, the commercial poultry industry was, for a long time, free of the highly pathogenic strain of the virus. This is now, unfortunately, no longer the case.

In the past, Veterinary Services was reluctant to allow vaccination of poultry in South Africa against AI. Most of the major international vaccine manufacturers have highly effective vaccines against AI, which are widely used in many countries where AI has become well-established. There were two reasons for this reluctance to allow vaccination against AI. Firstly, there is a well-organised and -run surveillance system in place for AI in South Africa. The basis of this monitoring programme is routinely looking for antibodies against AI in commercial poultry. This surveillance system is only possible if the birds are not vaccinated. The control policy in the past was a “stamping-out” policy. In other words, when AI is detected in a flock, the flock is destroyed. Secondly, AI has not been a major problem in South Africa in the past and the previous outbreaks were successfully controlled with the stamping-out policy which was in place. Previous AI outbreaks were successfully controlled. 

All this has now changed and AI is running rampant. The consequences of this will be severe.

The commercial poultry industry is based on two different types of birds – the layers and the broilers. The layers, as the name suggests, are the birds which lay eggs for human consumption. The broiler birds are the meat birds. In order to maintain the supply of both meat and eggs, there is a complex system of breeder birds, grandparents and great grandparents. These breeder birds are genetic line birds and play a critical role in keeping the market supplied with poultry products. If (and when) these breeder birds contract AI, they will die (either from the virus infection or from the control efforts). When this happens, the constant supply of hatching eggs needed to keep the layer and broiler farmers supplied with chickens to meet the constant demand for poultry products will be gone. In other words, there will be a major shortage of poultry. As poultry is the most affordable source of protein, this will cause major food shortages and additional hunger problems.

Antibodies vs viruses 

There are efforts to now import vaccines against AI. This will assist with the control of the disease in the long term, but will, unfortunately, not do much to control the current problem in the short term. The reason for this is that it takes time for vaccinated birds to develop antibodies against the virus. As soon as the birds are vaccinated, their immune system will start to make antibodies. Only when there are enough antibodies, will the birds be protected. It can take up to two weeks to get sufficient antibodies. Even then, if there is too much virus in the field, the immune response of the birds can still be overwhelmed. In simple terms, if the bird has a number of antibodies (let’s use an understandable number to explain) of 10 antibodies and there are nine viruses, the antibodies win and the birds are safe. If there are 10 antibodies, but 11 viruses – the viruses win and the birds die. Obviously, these numbers are not the real numbers and are just used as an explanation. In the major Newcastle disease (NCD) outbreak in the late 1990s, the birds had very high levels of antibodies against NCD and should have been protected. However, there was so much circulating virus that the immune system of the birds were overwhelmed and this outbreak was very difficult to control.

The only short-term option for control of AI in the current situation is good biosecurity. It is essential that good biosecurity is in place on the poultry farms. Only high-quality, registered disinfectants must be used for the biosecurity efforts. The ideal product would be one which is non-toxic to the birds and can be used to continually reduce the levels of viruses in the flocks. Until the vaccination programme can take effect, the only control option is a full continual disinfection programme which would include using the disinfectant in the drinking water, provided that the product is registered for this application and also to regularly spray the birds – again only if the product is registered for this application. The registration of a product ensures that the label claims can be substantiated and there is valid scientific evidence to support the claims made by the producers of the product. 

The long-term consequences of this AI infection coupled with the constant problems with load shedding will be the death blow to many small- and medium-sized poultry farmers. It may even become very difficult for the large poultry companies to survive the current crisis. In order to meet the demand for poultry products, South Africa will most likely become even more reliant on imported poultry products, which is another bone of contention.

News Archive

Heart diseases a time bomb in Africa, says UFS expert
2010-05-17

 Prof. Francis Smit

There are a lot of cardiac problems in Africa. Sub-Saharan Africa is home to the largest population of rheumatic heart disease patients in the world and therefore hosts the largest rheumatic heart valve population in the world. They are more than one million, compared to 33 000 in the whole of the industrialised world, says Prof. Francis Smit, Head of the Department of Cardiothoracic Surgery at the Faculty of Health Sciences at the University of the Free State (UFS).

He delivered an inaugural lecture on the topic Cardiothoracic Surgery: Complex simplicity, or simple complexity?

“We are also sitting on a time bomb of ischemic heart disease with the WHO (World Health Organisation) estimating that CAD (coronary artery disease) will become the number-one killer in our region by 2020. HIV/Aids is expected to go down to number 7.”

Very little is done about it. There is neither a clear nor coordinated programme to address this expected epidemic and CAD is regarded as an expensive disease, confined to Caucasians in the industrialised world. “We are ignoring alarming statistics about incidences of adult obesity, diabetes and endemic hypertension in our black population and a rising incidence of coronary artery interventions and incidents in our indigenous population,” Prof. Smit says.

Outside South Africa – with 44 units – very few units (about seven) perform low volumes of basic cardiac surgery. The South African units at all academic institutions are under severe threat and about 70% of cardiac procedures are performed in the private sector.

He says the main challenge in Africa has become sustainability, which needs to be addressed through education. Cardiothoracic surgery must become part of everyday surgery in Africa through alternative education programmes. That will make this specialty relevant at all levels of healthcare and it must be involved in resource allocation to medicine in general and cardiothoracic surgery specifically.

The African surgeon should make the maximum impact at the lowest possible cost to as many people in a society as possible. “Our training in fields like intensive care and insight into pulmonology, gastroenterology and cardiology give us the possibility of expanding our roles in African medicine. We must also remember that we are trained physicians as well.

“Should people die or suffer tremendously while we can train a group of surgical specialists or retraining general surgeons to expand our impact on cardiothoracic disease in Africa using available technology maybe more creatively? We have made great progress in establishing an African School for Cardiothoracic Surgery.”

Prof. Smit also highlighted the role of the annual Hannes Meyer National Registrar Symposium that culminated in having an eight-strong international panel sponsored by the ICC of EACTS to present a scientific course as well as advanced surgical techniques in conjunction with the Hannes Meyer Symposium in 2010.

Prof. Smit says South Africa is fast becoming the driving force in cardiothoracic surgery in Africa. South Africa is the only country that has the knowledge, technology and skills base to act as the springboard for the development of cardiothoracic surgery in Africa.

South Africa, however, is experiencing its own problems. Mortality has doubled in the years from 1997 to 2005 and half the population in the Free State dies between 40 to 44 years of age.

“If we do not need health professionals to determine the quality and quantity of service delivery to the population and do not want to involve them in this process, we can get rid of them, but then the political leaders making that decision must accept responsibility for the clinical outcomes and life expectancies of their fellow citizens.

“We surely cannot expect to impose the same medical legal principles on professionals working in unsafe hospitals and who have complained and made authorities aware of these conditions than upon those working in functional institutions. Either fixes the institutions or indemnifies medical personnel working in these conditions and defends the decision publicly.

“Why do I have to choose the three out of four patients that cannot have a lifesaving operation and will have to die on their own while the system pretends to deliver treatment to all?”

Prof. Smit says developing a service package with guidelines in the public domain will go a long way towards addressing this issue. It is also about time that we have to admit that things are simply not the same. Standards are deteriorating and training outcomes are or will be affected.

The people who make decisions that affect healthcare service delivery and outcomes, the quality of training platforms and research, in a word, the future of South African medicine, firstly need rules and boundaries. He also suggested that maybe the government should develop health policy in the public domain and then outsource healthcare delivery to people who can actually deliver including thousands of experts employed but ignored by the State at present.

“It is time that we all have to accept our responsibilities at all levels… and act decisively on matters that will determine the quality and quantity of medical care for this and future generations in South Africa and Africa. Time is running out,” Prof. Smit says.
 

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