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07 November 2019 | Story Leonie Bolleurs | Photo Leonie Bolleurs
Chemistry
Discussing progress in green energy and nuclear medicine during the recent ReMec2, were from the left: Dr Dumisani Kama (UFS), Prof Roger Alberto (University of Zurich), Prof Andreas Roodt (UFS), and Dr Orbett Alexander (UFS).

Scientists in South Africa and Switzerland, with a research collaboration of 20 years, are working together to make a difference. A major focus of their work is nuclear medicine and green energy. 

Since the end of October, 22 speakers from five countries met for five days at four different sites in South Africa to discuss their work during the second symposium on reaction mechanisms, better known as ReMec2. The Department of Chemistry at the University of the Free State (UFS) hosted this event. 

Considerable reduction of carbon dioxide

According to Prof Andreas Roodt, lead researcher from the UFS Department of Chemistry, ReMec2 focused mainly on two projects: nuclear medicine and an R8 million project titled: Solar Light-driven Homogeneous Catalysis for Greener Industrial Processes with H2 (hydrogen gas) as Energy Source and CO2 (carbon dioxide) as C1 Building Block. This is a sunlight-driven project in search of new catalysts, which are chemical compounds that make the reactions faster and more effective, but which are not consumed during the reaction. The aim is to provide greener industrial processes with hydrogen as energy source, and to reduce carbon dioxide in the environment.

This research, if applied, has the probability of preventing the release of more than 100 kg of harmful carbon dioxide for every one kg of hydrogen produced. “Together with the Swiss group, we are at that stage of the research where these compounds, with just one molecule of the catalyst, can make 80 000 hydrogen molecules (very clean energy, as hydrogen in a car's engine burns to clean water; not like gasoline that burns to harmful carbon dioxide),” Prof Roodt explains. 

The UFS and the research group from Prof Robert Alberto at the University of Zurich have been working together on this research for the past twenty years. According to Prof Roodt, they are studying complete reaction mechanisms, including the time profile of how the different chemical compounds are reacting with each other and not just the simple product analysis as studied by most groups in the world. 

International patent on nuclear medicine

In June 2019, they registered an international patent on nuclear medicine model compounds. The patent was granted. During ReMec2, a lecture was presented on this patent, according to which a compound with an imaging isotope [Tc-99m] that has its own ‘X-rays’, can shed light on an affected organ in the human body for doctors to see where medicine should be administered. The same compound also contains the medicine to treat the disease. 

The work of these scientists is 100% in line with South Africa’s National Development Plan and it supports the UFS Strategic Plan. “The programme also builds on students’ research and increases network and collaboration possibilities. We receive more international acknowledgement for our research efforts and compete with the best in the world. Our research is not necessarily about having the best equipment (although it is very important), but critically it is about the generation of innovative ideas,” says Prof Roodt. 

News Archive

First doctorate in Thoracic Surgery in Africa awarded
2009-05-12

The University of the Free State (UFS) has become the first university in Africa to award a Ph.D. degree in Thoracic Surgery. The degree was conferred on Prof. Anthony Linegar from the university’s Department of Cardiothoracic Surgery during its recent graduation ceremony.

Thoracic surgery is a challenging subspecialty of cardiothoracic surgery. It began in South Africa in the 1940s and is a broad medico-surgical specialist discipline that involves the diagnosis, operative and peri-operative treatment of acquired and congenital non-cardiac ailments of the chest.

Prof. Linegar became the first academic to conduct a mixed methods analysis of this surgical specialty, which included a systematic review of all the research done in this field in South Africa. The title of his thesis is A Model for the Development of Thoracic Surgery in Central South Africa. The research was based on the hypothesis of a performance gap between the burden of disease in the community and the actual service provision. It makes use of systems theory and project management concepts to develop a model aimed at the development of thoracic surgery.

The research proved that there is a significant under provision of clinical services in thoracic surgery. This was quantified to a factor of 20 times less than should be the case, in diseases such as lung and oesophagus cancer. According to Prof. Linegar, there are multiple reasons for this. Listed amongst these reasons is the fact that thoracic surgery is not part of the undergraduate education in medical training. There tends to be a low level of awareness amongst clinicians as to what the thoracic surgeon offers their patients. The diagnostic and referral patterns in primary and secondary health facilities, where diseases must be picked up and referred early, are not functioning well in this regard. In addition, relatively few cardiothoracic surgeons express an interest in thoracic surgery.

Prof. Linegar’s model is named the ATLAS Mode, which is an acronym for the Advancement of Thoracic Surgery through Analysis and Strategic Planning. It includes the raising of awareness of the role of the specialist thoracic surgeon in the treatment of patients with thoracic diseases as part of the solution to the problem. Furthermore, it aims to develop an accessible and sustainable specialist service that adequately provides for the needs of the community, and that is appropriately represented in health administration circles.

His promoters were Prof. Gert van Zyl, Head of the School of Medicine at the UFS, Prof. Peter Goldstraw, from the Imperial College of London, United Kingdom (UK) and Prof. Francis Smit, Head of the Department of Cardiothoracic Surgery at the UFS.

Prof. Linegar has been with the UFS since 2004, is a graduate from Stellenbosch University in 1984 and completed his postgraduate training in Cardiothoracic Surgery at the University of Cape Town. He was granted a Fellowship in Thoracic Surgery at the Royal Brompton Hospital in London, UK and has since held consultant positions at the UFS, Stellenbosch University and in private practice. He has been involved in registrar training since returning from the UK in 1994 and has extensive experience in intensive care medicine. He has published widely, has presented papers at many international conferences, has been invited as a speaker on many occasions and has won awards for best presentation on three occasions.

Media Release
Issued by: Lacea Loader
Assistant Director: Media Liaison
Tel: 051 401 2584
Cell: 083 645 2454
E-mail: loaderl.stg@ufs.ac.za  
12 May 2009
 

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