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10 June 2020 | Story Nitha Ramnath | Photo UFS Photo Archive
Prof Anthony Turton.
History was made in South Africa this week when a commercial laboratory became the first to extract COVID-19 RNA from various sewage samples in the country. This was done as a proof of concept, after the Dutch research agency KWR entered into an agreement with the SA Business Water Chamber on 9 April this year.

It was KWR that first demonstrated the potential of wastewater surveillance to identify the total viral load in a defined population in the Netherlands. This technology breakthrough has opened a new chapter in wastewater epidemiology on a global scale.
 
Prof Anthony Turton from the Centre for Environmental Management at the University of the Free State (UFS) says it is now possible to monitor the total viral load in each of the 824 wastewater treatment works in South Africa. Once the population size within the catchment area of the works is known, a calculation of the total viral load is possible, with a reasonable degree of accuracy. This accuracy will improve over time as the technology becomes more robust. 


Rapid deployment of technology
Prof Turton says this proof of concept is significant, because it took just eight weeks after reaching the agreement with KWR to find a laboratory with the necessary capabilities and to conduct the first tests. This is a rapid deployment of technology necessitated by the urgency of the COVID-19 pandemic. The source of funding for this demonstration was the private sector, so no taxpayer money was used. The proof of concept was deliberately designed to achieve two specific objectives. The main objective was to determine whether the Dutch methodology could be replicated in South Africa without major investment into training and procurement of laboratory equipment. The secondary objective was to understand the logistical complexities of sampling at multiple sewage works in one province, and then safely transporting those samples to the laboratory in another province. This emulates what will be needed if this methodology is adopted by government and rolled out across all provinces as required. 

Taking samples
Samples were taken over a 24-hour period using an automatic bulk sampler provided by a service provider at risk. A number of sewage works were sampled to emulate the complexity of a national operation should rapid implementation be required. The first samples were taken on Thursday 4 June. These were prepared according to a precise protocol and were shipped to the laboratory hundreds of kilometres away. The samples were prepared according to the stringent requirements of the protocol, and COVID-19 RNA was successfully extracted on Monday 8 June. Lessons learned in the first trial are being fed back to the team in preparation for the second sampling run that will take place shortly. 

Prof Turton, who serves in a facilitating role and in different capacities with each of the critical components of the overall value chain, is the man in the middle tying this whole process together. This is also a demonstration of the value of a university working in close collaboration with both government and private sector partners towards a common objective.  It is part of the Public Private Growth Initiative (PPGI), where the private sector works closely with the state to deliver core services needed to create employment opportunities as a matter of growing urgency.

Determining if the total viral load is increasing or decreasing
The second sampling run, which is about to be launched, will be a refinement of the first. Lessons learned during the logistical exercise will be applied to streamline the operation and generate an accurate costing of the service. By comparing the data for each sampling sequence, it will be possible to determine with a considerable degree of accuracy whether the total viral load in a given population is increasing or decreasing. When applied to multiple sewage works, it will be possible to identify hotspots for appropriate government intervention. This technical capability will provide robust information to both government and private sector decision-makers as they navigate their way through the complexity of a shutdown and phased re-opening of the national economy. Rapid upskilling of suitably qualified personnel will be needed, and the UFS will be playing a role in that process. 

News Archive

Exciting open day and Albert Einstein program at Boyden Observatory
2005-05-06

National Science Week, which will be held from 7-14 May 2005, is an annual country-wide celebration of science, led by the Department of Science and Technology.  The department selected a proposal by the Boyden Science Centre to coordinate a week of activities in the Bloemfontein area as one of the many projects in the country.

The project for Bloemfontein and surrounding areas will be delivered though a collaboration between the National Museum in Bloemfontein and the University of the Free State (UFS), including the Research Institute for Education Planning, the Department of Physics and other departments in the Faculty of Natural and Agricultural Sciences.

The purpose of National Science Week is:

to create awareness of the important role that science play in people’s daily lives;
to encourage our youth to consider studying and improving their performance in mathematics and science; and
to attract more of our youth into science, engineering and technology (SET) careers.

 

World Year of Physics and Albert Einstein Program at Boyden Observatory

The International Union of Pure and Applied Physics (IUPAP) declared the year 2005 as the World Year of Physics (WYP). In recognition of this declaration, the great contribution of Physics to the development of technology, and its importance in our everyday lives will be featured strongly during the National Science Week 2005.

On Saturday 7 May 2005 there will be a public programme at Boyden Observatory from 15:30 as a contribution to the World Year of Physics. The programme will be presented in collaboration with the Bloemfontein branch of the Astronomical Society of Southern Africa and will include short presentations on astronomy, space exploration and the sun.

The main presentation will be at 19:00 the evening on the life and work of Albert Einstein. The programme will also include observing sessions through telescopes of objects like the sun, Jupiter and Saturn. There will also be an exhibit on Albert Einstein. Attendance is free but booking is required.  For bookings, phone 051-4012561.

Public lecture programme:

Next week the following exciting public lectures will be presented as part of the Science Week activities:

Monday 9 May 2005 

National Museum:

A discussion on Apocalypse Then: the greatest mass extinction of all time.  The lecture will be presented by Dr Jennifer Botha, Paleontologist at the National Museum.
Bookings: 051-4479609 (entrance is free).

UFS campus:

All lectures at Kine 2, Medical Faculty, UFS campus. Follow directions from the DF Malherbe Road entrance.
Bookings: 051-4012561 (entrance is free).

Tuesday 10 May 2005:

A discussion on the Tsunami disaster of 26 December 2004 at 19:30 (UFS campus, Kine 2 Medical Faculty).

Wednesday 11 May 2005:

A discussion on Is there life out there? at 19:30 (UFS campus, Kine 2 Medical Faculty).

Friday 13 May 2005:

A discussion on Hunting Black Holes at 19:30 (UFS campus, Kine 2 Medical Faculty).  The lecture will be presented by Dr Phil Charles, Director: South African Astronomical Observatory.

Science awareness day at the National museum

The science week will be concluded on Saturday 14 May 2005 with a special Science Awareness Day at the National Museum, Aliwal Street, Bloemfontein. 

The excellent exhibits at the museum will be supplemented with activities, career information and video shows. The duration of the programme will be from 10:00-16:00.  For enquiries, please call 051-4479609.

 

Issued by:  Lacea Loader
   Media Representative
   Tel:  (051) 401-2584
   Cell:  083 645 2454
   E-mail:  loaderl.stg@mail.uovs.ac.za

6 May 2005
 

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