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UFS celebrates excellence through its research hubs
The university considers its research chairs and the possibility of future chairs as an integral and strategic initiative to increase its national and international standing through excellent academic and research leadership.

The University of the Free State (UFS) is proud of its research leaders. As of 2018 the UFS has 156 NRF-rated researchers and five Sarchi Research Chairs. These chairs are designed to attract and retain excellence in research and innovation at South African public universities.

Getting the better of vector borne and zoonotic viruses

Prof Felicity Burt leads the Vector Borne and Zoonotic Virus Research Group in the Department of Medical Microbiology and Virology at the UFS. She was awarded a Research Chair to, among others, investigate medically significant vector-borne and zoonotic viruses currently circulating - mainly viruses transmitted by mosquitos and ticks, and viruses transmitted from animals to humans. 

“Years ago, no one knew what Ebola was. One outbreak later, backed by many media reports, and it is almost a household name. The same goes for the recent Zika virus outbreak in South America,” she explains the public’s interest and fears. To prevent the spread of vector-borne viruses to new areas, surveillance and awareness is important. Here in Bloemfontein, Prof Burt and her team are establishing surveillance programmes.

Why research on fungal infections?

“Many diseases no longer pose a threat to humans and life expectancy is prolonged. However, this has also caused an increase in various opportunistic infections, and most of all, fungal infections,” says Prof Carlien Pohl-Albertyn, who is heading the Research Chair for Pathogenic Yeasts in the Department of Microbial, Biochemical and Food Biotechnology. And the rise in resistance to antifungal treatments requires research into pathobiology, including new drug and treatment options. 

Activities of the Research Chair in Pathogenic Yeasts builds on existing research strengths and will contribute towards understanding pathobiology of medically significant pathogenic yeasts belonging to the genera Candida and Cryptococcus. 

Understanding higher education for more equality and justice

Prof Melanie Walker, from the Centre for Research on Higher Education and Development (CRHED) does research on higher education, inequalities and social justice, and how, or if, universities foster the human capabilities and aspirations of students. Does higher education make a difference to the lives of students, their families and communities? 

Prof Walker says the Research Chair on Higher Education and Human Development looks at issues of access, participation and transitions into work, as well as gender, race and social class. They use both quantitative and qualitative methods and includes a strand of participatory research projects with students. Ultimately, the research must contribute to debates, policy and practices in higher education, and a scholarly knowledge base.

Reduced emissions make for a better world

Prof Hendrik Swart chairs the research project that looks into low-energy lighting, using phosphor materials for light emitting diodes (LEDs). The Research Chair on Solid State Luminescent and Advanced Materials is situated at the Department of Physics

The research mainly focuses on better light emission of phosphor powers in LEDs.  According to Prof Swart, the long-term benefit of the research will result in more environmentally friendly devices which use less energy, are brighter and give a wider viewing field. Over the next five years they will develop and produce devices that emit better light using the substances already developed. “We need to make small devices to see if they are better than those we already have,” he says. 

Solutions to food insecurity
 

The Department of Plant Sciences’s research project dives into disease resistance and quality in field crops. Heading this Research Chair is Prof Maryke Labuschagne who focuses on crop quality breeding and disease resistance in field crops. 

Her, and her students’ research focuses on the genetic improvement of food security crops in Africa, including such staples as maize and cassava. “These crops are genetically improved for yield, drought tolerance, disease, and insect resistance, as well nutritional value,” she says. Her disease resistance research will focus on crop protein quantity and quality as well as iron, zinc, and beta-carotene biofortification of staple crops such as wheat, maize and cassava. The disease resistance-breeding project will be a continuation of the internationally acclaimed wheat rust research. 

The university considers the research chairs and the possibility of future chairs as an integral and strategic initiative to increase its national and international standing through excellent academic and research leadership. 

Microbiology from University of the Free State on Vimeo.

News Archive

Higher than expected prevalence of dementia in South African urban black population
2010-09-22

 Prof. Malan Heyns and Mr Rikus van der Poel

Pilot research done by University of the Free State (UFS) indicates that the prevalence of dementia, of which Alzheimer’s disease is only one of the causes, is considerably higher than initially estimated. Clinical tests are now underway to confirm these preliminary findings.

To date it has been incorrectly assumed that dementia is less prevalent among urban black communities. This assumption is strongly disputed by the findings of the current study, which indicates a preliminary prevalence rate of approximately 6% for adults aged 65 years and older in this population group. Previous estimates for Southern Africa have been set at around 2,1%.

The research by the Unit for Professional Training and Services in the Behavioural Sciences (UNIBS) at the UFS and Alzheimer’s South Africa is part of the International 10/66 Dementia Research Group’s (10/66 DRG) initiative to establish the prevalence of dementia worldwide.

Mr Rikus van der Poel, coordinator of the local study, and Prof. Malan Heyns, Principal Investigator, say worldwide 66% of people with dementia live in low and middle income countries. It is expected that it will rise to more than 70% by 2040, and the socio-economic impact of dementia will increase accordingly within this period. 21 September marks World Alzheimer’s Day, and this year the focus is on the global economic impact of dementia. Currently, the world wide cost of dementia exceeds 1% of the total global GDP. If the global cost associated with dementia care was a company, it would be larger than Exxon-Mobil or Wal-Mart.

The researchers also say that of great concern is the fact that South Africa’s public healthcare system is essentially geared toward addressing primary healthcare needs, such as HIV/Aids and tuberculosis. The adult prevalence rate of HIV was 18,1% in 2007. According to UNAIDS figures more than 5,7 million people in South Africa are living with HIV/Aids, with an estimated annual mortality of 300 000. In many instances the deceased are young parents, with the result that the burden of childcare falls back on the elderly, and in many cases elderly grandparents suffering from dementia are left without children to take care of them. “These are but a few reasons that highlight the need for advocacy and awareness regarding dementia and care giving in a growing and increasingly urbanized population,” they say.

Low and middle income countries often lack epidemiological data to provide representative estimates of the regional prevalence of dementia. In general, epidemiological studies are challenging and expensive, especially in multi-cultural environments where the application of research protocols relies heavily on accurate language translations and successfully negotiated community access. Despite these challenges, the local researchers are keen to support advocacy and have joined the international effort to establish the prevalence of dementia through the 10/66 DRG.

The 10/66 DRG is a collective of researchers carrying out population-based research into dementia, non-communicable diseases and ageing in low and middle income countries. 10/66 refers to the two-thirds (66%) of people with dementia living in low and middle income countries, and the 10% or less of population-based research that has been carried out in those regions.

Since its inception in 1998, the 10/66 DRG has conducted population based surveys in 14 catchment areas in ten low and middle income countries, with a specific focus on the prevalence and impact of dementia. South Africa is one of seven LAMICs (low and medium income countries) where new studies have been conducted recently, the others being Puerto Rico, Peru, Mexico, Argentina, China and India.

Mr Van der Poel says participating researchers endeavour to conduct cross-sectional, comprehensive, one-phase surveys of all residents aged 65 and older within a geographically defined area. All centres share the same core minimum dataset with cross-culturally validated assessments (dementia diagnosis and subtypes, mental disorders, physical health, anthropometry, demographics, extensive non-communicable risk factor questionnaires, disability/functioning, health service utilization and caregiver strain).

The local pilot study, funded by Alzheimer’s South Africa, was rolled out through an existing community partnership, the Mangaung University of the Free State Community Partnership Programme (MUCPP).

According to Mr Van der Poel and Prof. Heyns, valuable insights have been gained into the myriad factors at play in establishing an epidemiological research project. The local community has responded positively and the pilot phase in and of itself has managed to promote awareness of the condition. The study has also managed to identify traditional and culture-specific views of dementia and dementia care. In addition, existing community-based networks are being strengthened, since part of the protocol will include the training and development of family caregivers within the local community in Mangaung.

“Like most developing economies, the South African population will experience continued urbanization during the next two decades, along with increased life expectancy. Community-based and residential care facilities for dementia are few and far between and government spending will in all probability continue to address the high demands associated with primary healthcare needs. These are only some of the reasons why epidemiological and related research is an important tool for assisting lobbyists, advocates and policymakers in promoting better care for those affected by dementia.”

Media Release
Issued by: Mangaliso Radebe
Assistant Director: Media Liaison
Tel: 051 401 2828
Cell: 078 460 3320
E-mail: radebemt@ufs.ac.za  
21 September 2010

 

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