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06 July 2018 Photo Supplied
Five PhDs for Chemistry group at June 2018 graduation
Pictured here are the Department of Chemistry graduates and their promoters/ co-promoters. From the left are: Dr Alebel Belay, Dr Dumisani Kama, Dr Orbett Alexander, Dr Pennie Mokolokolo and Dr Pule Molokoane; back: Prof Andreas Roodt, Dr Marietjie Schutte-Smith, Dr Alice Brink and Dr Johan Venter. Prof Roodt was either promoter or co-promoter to four of the graduates, while Prof Deon Visser (promoter; not present) and Dr Alice Brink (co-promoter) supervised Dr Orbett Alexander.

What is the common factor among metal extraction from mineral reserves, the treatment of cancer, and nanomaterials in cellular phones? The answer is Chemistry. 

For the first time since the Department of Chemistry at the University of the Free State (UFS) was founded some 114 years ago, a single research group in Chemistry delivered five PhD students.  This was achieved in the division of Inorganic Chemistry at the 2018 Winter graduation ceremony by the group under leadership of Prof Andreas Roodt and senior colleagues, Drs Johan Venter, Alice Brink and Marietjie Schutte-Smith. Prof Deon Visser, a former group member, was promoter for one of the students. 

The five graduandi are Drs Alebel Belay, Dumisani Kama, Pennie Mokolokolo, Pule Molokoane and Orbett Alexander. Their research involved the use of special chemical groups which are attached to metals such as platinum, rhodium, niobium, technetium and rhenium to create compounds with special pre-selected properties. 

The combination of these special groups with the metals allow many different potential applications – all adding value. These include metal extraction from South Africa’s rich mineral reserves, the treatment of diseases such as cancer, the diagnosis of heart and brain damages, nanomaterials which are used in cellular phones, catalysts to produce cleaner petrol, special light devices which by themselves ‘glow in the dark’, and more. 

Three of the students completed part of their research in Switzerland.

News Archive

Newly operational sequencing unit in genomics at UFS
2016-09-09

Description: Next Generation Sequencing  Tags: Next Generation Sequencing

Dr Martin Nyaga and his research assistant,
Tshidiso Mogotsi in the Next Generation
Sequencing Laboratory.
Photo: Charl Devenish

The Next Generation Sequencing (NGS) unit at the UFS was established as an interdisciplinary facility under the Directorate for Research Development, Faculty of Health Sciences and Faculty of Natural and Agricultural Sciences.

The aim of the NGS facility is to aid internal and external investigators undertaking studies on Deoxyribonucleic acid (DNA) sequencing, assembly and bioinformatics approaches using the more advanced Illumina MiSeq NGS platform.

The NGS unit became operational in 2016 and is managed by Dr Martin Nyaga and administered through the office of the Dean, Faculty of Health Sciences, under the leadership of Prof Gert Van Zyl. Dr Nyaga has vast experience in microbial genomics, having done his PhD in Molecular Virology.

He has worked and collaborated with globally recognised centres of excellence in Prokaryotic and Eukaryotic genomics, namely the J. Craig Venter Institute and the Laboratory of Viral Metagenomics, Rega Institute, among others.

The unit has undertaken several projects and successfully generated data on bacterial, viral and human genomes. Currently, work is ongoing on bacterial and fungal metagenomics studies through 16S rRNA sequencing.

In addition, the unit is also working on plasmid/insert sequencing and whole genome sequencing of animal and human rotaviruses. The unit has capacity to undertake other kinds of panels like the HLA, Pan-cancer and Tumor 15 sequencing, among others.

Several investigators from the UFS including but not limited to Prof Felicity Burt, Prof Wijnand Swart, Dr Frans O’Neil, Dr Trudi O'Neill, Dr Charlotte Boucher, Dr Marieka Gryzenhout and Dr Kamaldeen Baba are actively in collaboration with the NGS unit.

The unit has also invested in other specialised equipment such as the M220 Focused-ultrasonicator (Covaris), 2100 Bioanalyzer system (Agilent) and the real-time PCR cycler, the Rotor-Gene Q (Qiagen), which both the UFS and external investigators can use for their research.

Investigators working on molecular and related studies are encouraged to engage with Dr Nyaga on how they would like to approach their genomics projects at the UFS NGS unit. 

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