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31 October 2022 | Story Samkelo Fetile | Photo Tania Allen
Sne Mdletshe
Kovsie netball star and former Proteas netball team under-21 captain Sikholiwe Mdletshe hopes that she will inspire an entire generation both on and off the netball court.

Sikholiwe “Sne” Mdletshe’s passion and performance on the netball court makes her a force to be reckoned with. A fierce sportswoman and strong academic, Sne’s passion for her craft is also about inspiring those around her, and the next generation. This star netball player at the University of the Free State (UFS) scooped several Player of the Match awards during the 2022 Varsity Netball tournament, and she was also a clear crowd favourite. Despite the Kovsie netball team suffering a defeat in the semi-finals against North-West University (NWU), Mdletshe is grateful for the opportunity to live out her passion on the netball court. 

Where it all began

Mdletshe’s love for sports came very early in her life, and it was something for her to savour. “I have always had a passion for sports, whether it was athletics, soccer, or netball. I did it all – from primary school I played all the sports that were there, and in high school as well. I have just always been an active kid, and sports was a way to keep me busy,” she said.

Success and her family’s never-ending support helped motivate her. “My achievements in all the sporting codes really pushed me, from breaking records to getting the victrix ludorum award in Athletics [victrix ludorum is Latin for "the winner of the games", usually presented to the most successful team or competitor at a sports event], to getting Sports Star of the Year. Those were the things that really drove me to pursue and focus on sport. And of course, my family that pushed and supported me every step of the way.”

Balance between academics and sport

In 2019 Mdletshe captained the South African under-21 netball team while completing her BCom Accounting degree (which she completed cum laude). In 2020 she captained the UFS netball team. She also received her first call-up to the national Proteas netball team, for which she now has two caps. In 2021 she completed her BCom Accounting honours degree and is currently pursuing her Postgraduate Diploma in Chartered Accountancy. She believes that it is all possible through balancing, and she also hopes the next generation of students is encouraged to do extramural activities like sport.

“I came to the UFS in 2017 to study and play netball. Throughout the years, my lecturers have really helped me to find the perfect balance between academics and netball. The same can be done for the next generation of students, and a lot more can be achieved, individually and for Kovsie Sport as a programme.”

SA netball making strides

Mdletshe said she is not dissuaded by the slow growth of netball in South Africa. “Netball’s progress in being considered a professional sport in SA is steadily growing. We see the progress made in terms of players being paid to play netball. Earlier this year, a squad of contracted players was announced, and I am really looking forward to seeing some more growth and development in netball as a sport, especially it being considered a professional sport in the country, where many more netball players can be brought into the system. Big tournaments like the Varsity Netball Tournament make me very hopeful, and there is already a significant level of growth and interest shown in the sport. The way things are going gives a lot of encouragement to the younger generation who can possibly pursue netball as a professional career.”

Gratitude to all

Mdletshe gave a lot of praise to the Kovsie community. “I am honoured to have represented the UFS in varsity sports. For my performances, I would like to thank the coach and all my teammates for always pushing me. Gratitude to all the role players and most importantly to all our fans, who came out in numbers to rally behind us.”

She added: “Your journey in sports and in life will not be the same as the person next to you, and do not let that demotivate you. Take your time, make decisions that are best for yourself, and trust that your path will lead you exactly where your heart desires to be.”

News Archive

Nuclear Medicine on the forefront of cancer research
2017-07-10

Description: Nuclear Medicine on the forefront of cancer research Tags: Nuclear Medicine, cancer research, Dr Je’nine Horn-Lodewyk’s, tumour detection method, cancer, Department of Nuclear Medicine 

Dr Je’nine Horn-Lodewyk’s tumour detection method
could be the cost-effective breakthrough needed to decrease
the mortality rate in breast cancer patients.
Photo: Anja Aucamp

The field of Nuclear Medicine in South Africa and the rest of the world are expanding rapidly due to the development of hybrid cameras and new radiopharmaceuticals. These developments have a huge impact on the diagnosis and therapy of cancer.

The most advanced of these cameras, Positron emission tomography combined with normal CTs (PETCT), are not yet widely available in South Africa due to the cost of the cameras and the radiopharmaceuticals. A more cost-effective alternative can be of great benefit. To achieve this, the focus should be on developing new radiopharmaceuticals that can be used with the current cost-effective gamma cameras, according to University of the Free State researcher, Dr Je’nine Horn-Lodewyk from the Department of Nuclear Medicine.

Fluorodeoxyglucose (18F-FDG), a radiolabelled glucose analogue, is currently the radiopharmaceutical most commonly used in PET/CT imaging for mainly oncology indications. Although it is considered the gold standard for imaging in several malignancies, it does have certain disadvantages. An 18F-FDG PET/CT diagnostic imaging study can cost between R25 000 and R35 000 for a single patient in the private sector. The 18F-FDG is also more radioactive, which requires much stricter handling and shielding to avoid high radiation dosages to staff and patients.

Successful research potential innovative solution
In the search for the ideal radiopharmaceutical for tumour detection, the South African National Nuclear Energy Corporation (Necsa) developed a local synthesis process for ethylenedicysteine-deoxyglucose (EC-DG). EC-DG is also a glucose analogue similar to FDG. They succeeded in labelling the compound with Technetium-99-metastable-pertechnetate (99mTcO4-), the most common nuclear medicine isotope used for approximately 95% of nuclear medicine procedures, creating 99mTc-EC-DG.

In partnership with Dr Horn-Lodewyk, this compound was successfully used in various animal models and clinical scenarios, resulting in approval by the Medicine Control Council to use it in a human study. Research is also planned in order to investigate diagnostic accuracy in other cancers like lymphoma.  The end result of this research can produce a radiopharmaceutical that is cost effective, does not require the use of costly specialised equipment, has no significant side-effects, no special patient preparation, renders late imaging possible, and has decreased radiation risks.

Dr Horn-Lodewyk is grateful for the support of her mentor, Prof Anton Otto, as well as Dr Gert Engelbrecht, Head of the Department of Nuclear Medicine, Prof Jan Rijn Zeevaart from North-West University’s Preclinical Drug Development Platform and Necsa, and Judith Wagener from Necsa. This innovative research would also not have been possible without the financial assistance of Dr Glen Taylor and Eleanor van der Westhuizen in the Directorate of Research Development.

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