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13 September 2022 | Story Prof Jan du Plessis and André Damons | Photo Istock
Prof_Jan-DuPlessis
Prof Jan du Plessis is the Head of the Paediatric Oncology Unit at the University of the Free State (UFS).

A post on Facebook by a bereaved parent of a young child who tragically died of cancer that reads: “I want my old life back, the one with my child in it”, is unfortunately still the sad reality that many families face, even though in developed countries the overall survival rate for childhood cancer is now over 80%. For some types of cancer and in developing countries such as South Africa, the rate is much lower. There are some childhood cancers for which there is no treatment and which are uniformly fatal. 

Another harsh reality, according to Prof Jan du Plessis, Head of the Paediatric Oncology Unit at the University of the Free State (UFS), is that some of those who do survive cancer can go on to suffer long-term (sometimes life-long) health issues as a result of their treatment. Almost all cancer treatments used in children today were actually developed for adults. Most of these treatments (such as chemotherapy or radiotherapy) target all fast-growing cells (not just cancer cells), and this leads to harsh side-effects in young, growing bodies. 

Prof du Plessis says the need for more effective and safer treatments for children is urgent. Despite better outcomes for children diagnosed with cancer, some do not survive. Currently, between 800 to a 1 000 South African children are diagnosed with cancer annually. However, it’s estimated that half of the children with cancer in South Africa are never diagnosed, according to the Cancer Association of South Africa (CANSA)

Different types of Childhood Cancer

Children can get many different types of cancer. Some of the most common childhood cancers are:
• Leukaemia – cancer of the blood and bone marrow, which is the most common childhood cancer.
• Brain cancer – cancer that grows in the brain which is the second most common childhood cancer. It kills more children than any other type of cancer.
• Neuroblastoma & Nephroblastoma – the most common solid tumours diagnosed in children under the age of five.
• Sarcoma – a cancer that grows in the bones and connective tissues of the body.
• Lymphoma – cancer that develops in the lymphatic system.

St Siluan Warning Signs of Childhood Cancer:

According to CHOC Childhood Cancer Foundation South Africa, research showed that an ongoing awareness campaign on the early warning signs was needed to improve the rate of referrals at an earlier stage of the disease. It is for this reason that 15 February (International Childhood Cancer Day), and the month of September, that marks Childhood Cancer Awareness Month, are important for awareness. 

“It is not possible to prevent cancer in children, but significant improvements can be made in their lives by detecting cancer early and avoiding delays in care. A correct diagnosis is important to treat children with cancer because each cancer involves a specific treatment regimen that may include surgery, radiotherapy, and chemotherapy.

“To improve early diagnosis we try to educate the public/students on the early warning signs of childhood cancer. We use the St Siluan Warning Signs for Childhood Cancer,” explains Prof Du Plessis. 

S – Seek medical help early for ongoing symptoms
I – White spot in the eye, new squint, sudden blindness or bulging eyeball
L – Lump on the stomach, pelvis, head, arms, legs, testicle or glands
U – Unexplained fever present for more than two weeks, weight loss, fatigue, pale appearance, easy bruising and bleeding
A – Aching bones, joints, back and easy fractures
N – Neurological signs, a change in walk, balance or speech, regression, continuous headaches with / without vomiting and enlarged head

According Prof du Plessis, his hope is to diagnose these kids early, the earlier they are diagnosed, the less treatment they are exposed. It is amazing to witness how the cancer kids adapt to their new normal and reality, says Prof Du Plessis. 

“They play soccer in the corridor, not in the park. One in fact learnt to walk in the hospital. Nurses and doctors become their new family. Their joy, strength and resilience is remarkable. Their laughter will make your heart melt. Your life will be forever changed, seeing a child fight cancer.”

News Archive

The state of HIV/AIDS at the UFS
2010-05-11

“The University of the Free State (UFS) remains concerned about the threat of HIV/AIDS and will not become complacent in its efforts to combat HIV/AIDS by preventing new infections”, states Ms Estelle Heideman, Manager of the Kovsies HIV/AIDS Centre at the UFS.

She was responding to the results of a study that was done at Higher Education Institutions (HEIs) in 2008. The survey was initiated by Higher Education AIDS (HEAIDS) to establish the knowledge, attitudes, behaviours and practices (KABP) related to HIV and AIDS and to measure the HIV prevalence levels among staff and students. The primary aim of this research was to develop estimates for the sector.

The study populations consisted of students and employees from 21 HEIs in South Africa where contact teaching occurs. For the purpose of the cross-sectional study an ‘anonymous HIV survey with informed consent’ was used. The study comprised an HIV prevalence study, KABP survey, a qualitative study, and a risk assessment.

Each HEI was stratified by campus and faculty, whereupon clusters of students and staff were randomly selected. Self-administered questionnaires were used to obtain demographic, socio-economic and behavioural data. The HIV status of participants was determined by laboratory testing of dry blood spots obtained by finger pricks. The qualitative study consisted of focus group discussions and key informant interviews at each HEI.

Ethical approval was provided by the UFS Ethics Committee. Participation in all research was voluntary and written informed consent was obtained from all participants. Fieldwork for the study was conducted between September 2008 and February 2009.

A total of 1 004 people participated at the UFS, including the Main and the Qwaqwa campuses, comprising 659 students, 85 academic staff and 256 administration/service staff. The overall response rate was 75,6%.

The main findings of the study were:

HIV prevalence among students was 3,5%, 0% among academics, 1,3% among administrative staff, and 12,4% among service staff. “This might not be a true reflection of the actual prevalence of HIV at the UFS, as the sample was relatively small,” said Heideman. However, she went on to say that if we really want to show our commitment towards fighting this disease at our institution a number of problem areas should be addressed:

  • Around half of all students under the age of 20 have had sex before and this increased to almost three-quarters of students older than 20.

     
  • The majority of staff and a third of students had ever been tested for HIV.

     
  • More than 50% of students drink more than once per week and 44% of students reported being drunk in the past month. Qualitative data suggests that binge drinking over weekends and at campus ‘bashes’ is an area of concern.

Recommendations of the study:

  • Emphasis should be on increased knowledge of sexual risk behaviours, in particular those involving a high turnover of sexual partners and multiple sexual partnerships. Among students, emphasis should further be placed on staying HIV negative throughout university study.

     
  • The distribution of condoms on all campuses should be expanded, systematised and monitored. If resistance is encountered, attempts should be made to engage and educate dissenting institutional members about the importance of condom use in HIV prevention.

     
  • The relationship between alcohol misuse and pregnancy, sexually transmitted infections (STIs), HIV and AIDS needs to be made known, and there should be a drive to curb high levels of student drinking, promote non-alcohol oriented forms of recreation, and improve regulation of alcohol consumption at university-sponsored “bashes”.

     
  • There is need to reach out to students and staff who have undergone HIV testing and who know their HIV status, but do not access or benefit from support services. Because many HIV-positive students and staff are not receiving any kind of support, resources should be directed towards the development of HIV care services, including support groups.

Says Heideman, “If we really want to prove that we are serious about an HIV/AIDS-free campus, these results are a good starting point. It definitely provides us with a strong basis from which to work.” Since the study was done in 2008 the UFS has committed itself to a more comprehensive response to HIV/AIDS. The current proposed ‘HIV/AIDS Institutional response and strategic plan’, builds and expands on work that has been done before, the lessons learned from previous interventions, and a thorough study of good practices at other universities.

Media Release
Issued by: Mangaliso Radebe
Assistant Director: Media Liaison
Tel: 051 401 2828
Cell: 078 460 3320
E-mail: radebemt@ufs.ac.za  
10 May 2010

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