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13 September 2022 | Story Prof Jan du Plessis and André Damons | Photo Istock
Prof_Jan-DuPlessis
Prof Jan du Plessis is the Head of the Paediatric Oncology Unit at the University of the Free State (UFS).

A post on Facebook by a bereaved parent of a young child who tragically died of cancer that reads: “I want my old life back, the one with my child in it”, is unfortunately still the sad reality that many families face, even though in developed countries the overall survival rate for childhood cancer is now over 80%. For some types of cancer and in developing countries such as South Africa, the rate is much lower. There are some childhood cancers for which there is no treatment and which are uniformly fatal. 

Another harsh reality, according to Prof Jan du Plessis, Head of the Paediatric Oncology Unit at the University of the Free State (UFS), is that some of those who do survive cancer can go on to suffer long-term (sometimes life-long) health issues as a result of their treatment. Almost all cancer treatments used in children today were actually developed for adults. Most of these treatments (such as chemotherapy or radiotherapy) target all fast-growing cells (not just cancer cells), and this leads to harsh side-effects in young, growing bodies. 

Prof du Plessis says the need for more effective and safer treatments for children is urgent. Despite better outcomes for children diagnosed with cancer, some do not survive. Currently, between 800 to a 1 000 South African children are diagnosed with cancer annually. However, it’s estimated that half of the children with cancer in South Africa are never diagnosed, according to the Cancer Association of South Africa (CANSA)

Different types of Childhood Cancer

Children can get many different types of cancer. Some of the most common childhood cancers are:
• Leukaemia – cancer of the blood and bone marrow, which is the most common childhood cancer.
• Brain cancer – cancer that grows in the brain which is the second most common childhood cancer. It kills more children than any other type of cancer.
• Neuroblastoma & Nephroblastoma – the most common solid tumours diagnosed in children under the age of five.
• Sarcoma – a cancer that grows in the bones and connective tissues of the body.
• Lymphoma – cancer that develops in the lymphatic system.

St Siluan Warning Signs of Childhood Cancer:

According to CHOC Childhood Cancer Foundation South Africa, research showed that an ongoing awareness campaign on the early warning signs was needed to improve the rate of referrals at an earlier stage of the disease. It is for this reason that 15 February (International Childhood Cancer Day), and the month of September, that marks Childhood Cancer Awareness Month, are important for awareness. 

“It is not possible to prevent cancer in children, but significant improvements can be made in their lives by detecting cancer early and avoiding delays in care. A correct diagnosis is important to treat children with cancer because each cancer involves a specific treatment regimen that may include surgery, radiotherapy, and chemotherapy.

“To improve early diagnosis we try to educate the public/students on the early warning signs of childhood cancer. We use the St Siluan Warning Signs for Childhood Cancer,” explains Prof Du Plessis. 

S – Seek medical help early for ongoing symptoms
I – White spot in the eye, new squint, sudden blindness or bulging eyeball
L – Lump on the stomach, pelvis, head, arms, legs, testicle or glands
U – Unexplained fever present for more than two weeks, weight loss, fatigue, pale appearance, easy bruising and bleeding
A – Aching bones, joints, back and easy fractures
N – Neurological signs, a change in walk, balance or speech, regression, continuous headaches with / without vomiting and enlarged head

According Prof du Plessis, his hope is to diagnose these kids early, the earlier they are diagnosed, the less treatment they are exposed. It is amazing to witness how the cancer kids adapt to their new normal and reality, says Prof Du Plessis. 

“They play soccer in the corridor, not in the park. One in fact learnt to walk in the hospital. Nurses and doctors become their new family. Their joy, strength and resilience is remarkable. Their laughter will make your heart melt. Your life will be forever changed, seeing a child fight cancer.”

News Archive

Heart diseases a time bomb in Africa, says UFS expert
2010-05-17

 Prof. Francis Smit

There are a lot of cardiac problems in Africa. Sub-Saharan Africa is home to the largest population of rheumatic heart disease patients in the world and therefore hosts the largest rheumatic heart valve population in the world. They are more than one million, compared to 33 000 in the whole of the industrialised world, says Prof. Francis Smit, Head of the Department of Cardiothoracic Surgery at the Faculty of Health Sciences at the University of the Free State (UFS).

He delivered an inaugural lecture on the topic Cardiothoracic Surgery: Complex simplicity, or simple complexity?

“We are also sitting on a time bomb of ischemic heart disease with the WHO (World Health Organisation) estimating that CAD (coronary artery disease) will become the number-one killer in our region by 2020. HIV/Aids is expected to go down to number 7.”

Very little is done about it. There is neither a clear nor coordinated programme to address this expected epidemic and CAD is regarded as an expensive disease, confined to Caucasians in the industrialised world. “We are ignoring alarming statistics about incidences of adult obesity, diabetes and endemic hypertension in our black population and a rising incidence of coronary artery interventions and incidents in our indigenous population,” Prof. Smit says.

Outside South Africa – with 44 units – very few units (about seven) perform low volumes of basic cardiac surgery. The South African units at all academic institutions are under severe threat and about 70% of cardiac procedures are performed in the private sector.

He says the main challenge in Africa has become sustainability, which needs to be addressed through education. Cardiothoracic surgery must become part of everyday surgery in Africa through alternative education programmes. That will make this specialty relevant at all levels of healthcare and it must be involved in resource allocation to medicine in general and cardiothoracic surgery specifically.

The African surgeon should make the maximum impact at the lowest possible cost to as many people in a society as possible. “Our training in fields like intensive care and insight into pulmonology, gastroenterology and cardiology give us the possibility of expanding our roles in African medicine. We must also remember that we are trained physicians as well.

“Should people die or suffer tremendously while we can train a group of surgical specialists or retraining general surgeons to expand our impact on cardiothoracic disease in Africa using available technology maybe more creatively? We have made great progress in establishing an African School for Cardiothoracic Surgery.”

Prof. Smit also highlighted the role of the annual Hannes Meyer National Registrar Symposium that culminated in having an eight-strong international panel sponsored by the ICC of EACTS to present a scientific course as well as advanced surgical techniques in conjunction with the Hannes Meyer Symposium in 2010.

Prof. Smit says South Africa is fast becoming the driving force in cardiothoracic surgery in Africa. South Africa is the only country that has the knowledge, technology and skills base to act as the springboard for the development of cardiothoracic surgery in Africa.

South Africa, however, is experiencing its own problems. Mortality has doubled in the years from 1997 to 2005 and half the population in the Free State dies between 40 to 44 years of age.

“If we do not need health professionals to determine the quality and quantity of service delivery to the population and do not want to involve them in this process, we can get rid of them, but then the political leaders making that decision must accept responsibility for the clinical outcomes and life expectancies of their fellow citizens.

“We surely cannot expect to impose the same medical legal principles on professionals working in unsafe hospitals and who have complained and made authorities aware of these conditions than upon those working in functional institutions. Either fixes the institutions or indemnifies medical personnel working in these conditions and defends the decision publicly.

“Why do I have to choose the three out of four patients that cannot have a lifesaving operation and will have to die on their own while the system pretends to deliver treatment to all?”

Prof. Smit says developing a service package with guidelines in the public domain will go a long way towards addressing this issue. It is also about time that we have to admit that things are simply not the same. Standards are deteriorating and training outcomes are or will be affected.

The people who make decisions that affect healthcare service delivery and outcomes, the quality of training platforms and research, in a word, the future of South African medicine, firstly need rules and boundaries. He also suggested that maybe the government should develop health policy in the public domain and then outsource healthcare delivery to people who can actually deliver including thousands of experts employed but ignored by the State at present.

“It is time that we all have to accept our responsibilities at all levels… and act decisively on matters that will determine the quality and quantity of medical care for this and future generations in South Africa and Africa. Time is running out,” Prof. Smit says.
 

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