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Tebogo Machete
Tebogo Machethe has recently been appointed Director for Innovation and Contracts in the Directorate of Research Development (DRD) at the University of the Free State (UFS).

The recently appointed Director for Innovation and Contracts in the Directorate of Research Development (DRD) at the University of the Free State (UFS) would like to see the university’s research outcome being adopted by industry and research output translating into commercial opportunities and more income.

Tebogo Machethe, who is experienced in managing intellectual property and commercialising technologies, amongst other things, assumed his new role on 1 June and has felt right at home. He is looking forward to a good working relationship and environment with all the stakeholders. 

“I would also like to see a huge drive wherein the commercialisation activities and income of the university from commercialisation of Intellectual Property (IP) increases from the research been undertaken. We will also be intensifying the entrepreneurial drive at the university with a view to creating more entrepreneurship opportunities and skills for researchers and students. This will prepare our graduates to venture into entrepreneurship once they are done with their studies,” says Machethe.

According to him, South Africa now needs research that responds to the needs of society and provides solutions to society’s problems.  

Intellectual property, commercialising technologies, contracts 

Before joining the UFS, Machethe had been a Senior Manager: Technology Transfer at the University of Johannesburg for the past six years. He also spent some time at CIPRO (currently known as Companies and Intellectual Property Commission (CIPC) from 2004-2006 before joining Hahn & Hahn Inc as a Candidate patent attorney until late 2008. He then moved to the Council for Scientific and Industrial Research (CSIR): Materials Science and Manufacturing business unit in the Intellectual Property & Technology Transfer office. 

“Most of my duties revolved around managing intellectual property, commercialising technologies and drafting and managing contracts only related to IP and Technology Transfer. My current duties have expanded to all forms of contracts and also involvement in grant funding and other forms of funding,” says Machethe.

He says as a research office, the DRD exists in an eco-system wherein there are different role players. Through different role players, there is always a convergence of thinking and approaches which when all put together, puts the institution on a path to achieve the goals of the university.

Fun facts about Tebogo Machethe

  • He grew up in a small village called Ga-Raphahlelo, in Sekgosese, Mopani district, Limpopo. He is married with three children. 
  • When he is not pre-occupied with office matters, he tries to spend as much time with his family. He loves reading, running and cycling, which he often does.
  • He has lived for the last two decades in Pretoria and is finding the Free State winter challenging. “It feels personal,” he says. 

News Archive

Champagne and cancer have more in common than you might think
2013-05-08

 

Photo: Supplied
08 May 2013

No, a glass of champagne will not cure cancer....

…But they have more in common than you might think.

Researchers from the Departments of Microbial Biochemical and Food Biotechnology, Physics and the Centre for Microscopy at the University of the Free State in South Africa were recently exploring the properties of yeast cells in wine and food to find out more of how yeast was able to manufacture the gas that caused bread to rise, champagne to fizz and traditional beer to foam. And the discovery they made is a breakthrough that may have enormous implications for the treatment of diseases in humans.

The team discovered that they could slice open cells with argon gas particles, and look inside. They were surprised to find a maze of tiny passages like gas chambers that allowed each cell to ‘breathe.’ It is this tiny set of ‘lungs’ that puts the bubbles in your bubbly and the bounce in your bread.

But it was the technique that the researchers used to open up the cells that caught the attention of the scientists at the Mayo Clinic (Tumor Angiogenesis and Vascular Biology Research Centre) in the US.

Using this technology, they ultimately aim to peer inside cells taken from a cancer patient to see how treatment was progressing. In this way they would be able to assist the Mayo team to target treatments more effectively, reduce dosages in order to make treatment gentler on the patient, and have an accurate view of how the cancer was being eliminated.

“Yes, we are working with the Mayo Clinic,” said Profes Lodewyk Kock from the Microbial, Biochemical and Food Biotechnology Department at the UFS.

“This technique we developed has enormous potential for cell research, whether it is for cancer treatment or any other investigation into the working of cells. Through nanotechnology, and our own invention called Auger-architectomics, we are able to see where no-one has been able to see before.”

The team of Prof Kock including Dr Chantel Swart, Kumisho Dithebe, Prof Hendrik Swart (Physics, UFS) and Prof Pieter van Wyk (Centre for Microscopy, UFS) unlocked the ‘missing link’ that explains the existence of bubbles inside yeasts, and incidentally have created a possible technique for tracking drug and chemotherapy treatment in human cells.

Their work has been published recently in FEMS Yeast Research, the leading international journal on yeast research. In addition, their discovery has been selected for display on the cover page of all 2013 issues of this journal.

One can most certainly raise a glass of champagne to celebrate that!

There are links for video lectures on the technique used and findings on the Internet at:

1. http://vimeo.com/63643628 (Comic version for school kids)

2. http://vimeo.com/61521401 (Detailed version for fellow scientists)

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