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28 June 2023 | Story Nonsindiso Qwabe | Photo Sipplied
Dr Patricks Voua Otomo
Dr Patricks Voua Otomo says cholera is one of the most vicious threats to public health.

South Africa’s water challenges and dilapidating infrastructure could mean that cholera is here to stay. The recent cholera outbreaks in Gauteng and the Free State were a warning sign that the quality of the country’s water is questionable.

According to Dr Patricks Voua Otomo, Head of the Ecotoxicology Research Laboratory and Subject Head: Zoology and Entomology in the Faculty of Natural and Agricultural Sciences, we remain at risk of recurring and isolated outbreaks until the country’s failing water systems are addressed.

Systemic failure poses significant risks to public health

He warned that as long as the country’s wastewater treatment works are in a poor to critical state, they pose significant risks to public health and the environment.

“Our water systems are connected, and in South Africa one of our greatest challenges is poorly treated wastewater systems and highly polluted rivers. The current cholera outbreak isn’t happening in peculiar regions. It’s in areas where people consume questionable drinking water. The water we have is not of good quality, and people shouldn’t be consuming it,” he said.

Dr Otomo said that cholera is one of the most vicious threats to public health and an indicator of inequality, because bacteria may continue to thrive if the current conditions remain unchanged. “All it takes to get cholera is a drop of contaminated water in your system to fall sick or even die. In a country like ours, where many people experience water scarcity and rely on unsanitary water sources, they are vulnerable to being easily exposed to bacterial diseases such as cholera.”

Water treatment plants require urgent intervention

The current cholera outbreak could be subsiding, but he warns that it is only a matter of time before it resurfaces, or other waterborne diseases wreak havoc if things remain unchanged.

“We urgently need to address the failing infrastructure, improve the quality of our drinking water, and how water gets treated before being released into river streams – or we’ll remain at risk. Cholera is just one of many waterborne diseases. High E. coli levels were found on our beaches just recently, which is an indicator of other bacteria present in the water. We are really in trouble.”

News Archive

UFS cardiac team leading with project
2017-05-31

 Description: Cardiac team read more Tags: Cardiac team read more

Prof Peter Schultheiss of the Charité University in Berlin,
Germany, visited the Robert WM Frater Centre for
Cardiovascular Research at the UFS for a study regarding
cardiomyopathy, a significant cause of fatal heart failure
among Africans. From the left are Dr Glen Taylor,
Dr Danie Buys, Prof Makoali Makatoko,
Prof Schultheiss and Prof Francis Smit.
Photo: Rulanzen Martin

A team of cardiac doctors associated with the Robert WM Frater Cardiovascular Research Centre at the University of the Free State’s (UFS) Faculty of Health Sciences has commenced with a pioneering research project regarding idiopathic dilating cardiomyopathy.  

An Afrocentric research focus
Prof Francis Smit, Head of the Department of Cardiothoracic Surgery at the UFS and Head of the Frater Centre, describes dilating cardiomyopathy as a heart muscle disease that is quite common, particularly among people of African descent. The disease weakens the heart muscle, which in turn leads to heart failure.

“To date there is no curable treatment for this condition and 50% of patients that have shown heart failure, died within a period of five years. The causes of this condition have been unknown in the majority of patients. But over the past few years major strides have been made where virus infections of the heart muscle or myocarditis have been identified as a possible underlying cause. Various genetic diseases are also linked to it,” says Prof Smit.

International collaborations ensure success
According to Prof Smit, the project is being run in conjunction with Prof Heinz-Peter Schultheiss of the Charité University and the Institute for Cardiac Diagnostics and Therapy in Berlin, Germany.

“We have been working on the project over the past 18 months and I have twice visited Prof Schultheiss in Germany. He is now visiting us in Bloemfontein. We have established a collaborative project focused on patients in central South Africa”.
Prof Schultheiss is a world leader regarding the diagnosis, pathology and treatment of dilating cardiomyopathy, says Prof Smit.

“He brings a lifetime of research experience to Bloemfontein and is internationally renowned as the father of myocardial or heart muscle biopsies.

“His pioneering work on the discipline has led to diagnostic accuracy that has induced purposeful and personalised treatment of dilating cardiomyopathy and has brought about dramatic changes in some subsets of patients’ life expectancy and their cure.”

Solving problems close to home
According to Prof Mokoali Makatoko, Head of the Department of Cardiology, there are more than 1500 new cases of heart failure identified annually at the Universitas Academic Hospital, of which approximately 30% are attributed to cardiomyopathy. “With the use of endomyocardial biopsies the team hopes to treat viruses unique to Southern Africa as well as other underlying causes of dilating cardiomyopathy.”

Prof Stephen Brown, Head of Paediatric Cardiology at the Universitas Academic Hospital, says children suffering from this disease never reach a mature age and those under his supervision will also be undergoing these tests. Various other departments at the UFS will also participate in this project. Profs Makatoko and Brown did the first four endomyocardial biopsies under the management of Prof Schultheiss during the past week. The results will be available in the coming weeks after which the project will be officially launched and patient recruitment will start in earnest.

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