Latest News Archive

Please select Category, Year, and then Month to display items
Years
2019 2020 2021
Previous Archive
07 November 2019 | Story Leonie Bolleurs | Photo Leonie Bolleurs
Chemistry
Discussing progress in green energy and nuclear medicine during the recent ReMec2, were from the left: Dr Dumisani Kama (UFS), Prof Roger Alberto (University of Zurich), Prof Andreas Roodt (UFS), and Dr Orbett Alexander (UFS).

Scientists in South Africa and Switzerland, with a research collaboration of 20 years, are working together to make a difference. A major focus of their work is nuclear medicine and green energy. 

Since the end of October, 22 speakers from five countries met for five days at four different sites in South Africa to discuss their work during the second symposium on reaction mechanisms, better known as ReMec2. The Department of Chemistry at the University of the Free State (UFS) hosted this event. 

Considerable reduction of carbon dioxide

According to Prof Andreas Roodt, lead researcher from the UFS Department of Chemistry, ReMec2 focused mainly on two projects: nuclear medicine and an R8 million project titled: Solar Light-driven Homogeneous Catalysis for Greener Industrial Processes with H2 (hydrogen gas) as Energy Source and CO2 (carbon dioxide) as C1 Building Block. This is a sunlight-driven project in search of new catalysts, which are chemical compounds that make the reactions faster and more effective, but which are not consumed during the reaction. The aim is to provide greener industrial processes with hydrogen as energy source, and to reduce carbon dioxide in the environment.

This research, if applied, has the probability of preventing the release of more than 100 kg of harmful carbon dioxide for every one kg of hydrogen produced. “Together with the Swiss group, we are at that stage of the research where these compounds, with just one molecule of the catalyst, can make 80 000 hydrogen molecules (very clean energy, as hydrogen in a car's engine burns to clean water; not like gasoline that burns to harmful carbon dioxide),” Prof Roodt explains. 

The UFS and the research group from Prof Robert Alberto at the University of Zurich have been working together on this research for the past twenty years. According to Prof Roodt, they are studying complete reaction mechanisms, including the time profile of how the different chemical compounds are reacting with each other and not just the simple product analysis as studied by most groups in the world. 

International patent on nuclear medicine

In June 2019, they registered an international patent on nuclear medicine model compounds. The patent was granted. During ReMec2, a lecture was presented on this patent, according to which a compound with an imaging isotope [Tc-99m] that has its own ‘X-rays’, can shed light on an affected organ in the human body for doctors to see where medicine should be administered. The same compound also contains the medicine to treat the disease. 

The work of these scientists is 100% in line with South Africa’s National Development Plan and it supports the UFS Strategic Plan. “The programme also builds on students’ research and increases network and collaboration possibilities. We receive more international acknowledgement for our research efforts and compete with the best in the world. Our research is not necessarily about having the best equipment (although it is very important), but critically it is about the generation of innovative ideas,” says Prof Roodt. 

News Archive

UFS cardiac team leading with project
2017-05-31

 Description: Cardiac team read more Tags: Cardiac team read more

Prof Peter Schultheiss of the Charité University in Berlin,
Germany, visited the Robert WM Frater Centre for
Cardiovascular Research at the UFS for a study regarding
cardiomyopathy, a significant cause of fatal heart failure
among Africans. From the left are Dr Glen Taylor,
Dr Danie Buys, Prof Makoali Makatoko,
Prof Schultheiss and Prof Francis Smit.
Photo: Rulanzen Martin

A team of cardiac doctors associated with the Robert WM Frater Cardiovascular Research Centre at the University of the Free State’s (UFS) Faculty of Health Sciences has commenced with a pioneering research project regarding idiopathic dilating cardiomyopathy.  

An Afrocentric research focus
Prof Francis Smit, Head of the Department of Cardiothoracic Surgery at the UFS and Head of the Frater Centre, describes dilating cardiomyopathy as a heart muscle disease that is quite common, particularly among people of African descent. The disease weakens the heart muscle, which in turn leads to heart failure.

“To date there is no curable treatment for this condition and 50% of patients that have shown heart failure, died within a period of five years. The causes of this condition have been unknown in the majority of patients. But over the past few years major strides have been made where virus infections of the heart muscle or myocarditis have been identified as a possible underlying cause. Various genetic diseases are also linked to it,” says Prof Smit.

International collaborations ensure success
According to Prof Smit, the project is being run in conjunction with Prof Heinz-Peter Schultheiss of the Charité University and the Institute for Cardiac Diagnostics and Therapy in Berlin, Germany.

“We have been working on the project over the past 18 months and I have twice visited Prof Schultheiss in Germany. He is now visiting us in Bloemfontein. We have established a collaborative project focused on patients in central South Africa”.
Prof Schultheiss is a world leader regarding the diagnosis, pathology and treatment of dilating cardiomyopathy, says Prof Smit.

“He brings a lifetime of research experience to Bloemfontein and is internationally renowned as the father of myocardial or heart muscle biopsies.

“His pioneering work on the discipline has led to diagnostic accuracy that has induced purposeful and personalised treatment of dilating cardiomyopathy and has brought about dramatic changes in some subsets of patients’ life expectancy and their cure.”

Solving problems close to home
According to Prof Mokoali Makatoko, Head of the Department of Cardiology, there are more than 1500 new cases of heart failure identified annually at the Universitas Academic Hospital, of which approximately 30% are attributed to cardiomyopathy. “With the use of endomyocardial biopsies the team hopes to treat viruses unique to Southern Africa as well as other underlying causes of dilating cardiomyopathy.”

Prof Stephen Brown, Head of Paediatric Cardiology at the Universitas Academic Hospital, says children suffering from this disease never reach a mature age and those under his supervision will also be undergoing these tests. Various other departments at the UFS will also participate in this project. Profs Makatoko and Brown did the first four endomyocardial biopsies under the management of Prof Schultheiss during the past week. The results will be available in the coming weeks after which the project will be officially launched and patient recruitment will start in earnest.

We use cookies to make interactions with our websites and services easy and meaningful. To better understand how they are used, read more about the UFS cookie policy. By continuing to use this site you are giving us your consent to do this.

Accept