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10 June 2020 | Story Nitha Ramnath | Photo UFS Photo Archive
Prof Anthony Turton.

History was made in South Africa this week when a commercial laboratory became the first to extract COVID-19 RNA from various sewage samples in the country. This was done as a proof of concept, after the Dutch research agency KWR entered into an agreement with the SA Business Water Chamber on 9 April this year.

It was KWR that first demonstrated the potential of wastewater surveillance to identify the total viral load in a defined population in the Netherlands. This technology breakthrough has opened a new chapter in wastewater epidemiology on a global scale.
 
Prof Anthony Turton from the Centre for Environmental Management at the University of the Free State (UFS) says it is now possible to monitor the total viral load in each of the 824 wastewater treatment works in South Africa. Once the population size within the catchment area of the works is known, a calculation of the total viral load is possible, with a reasonable degree of accuracy. This accuracy will improve over time as the technology becomes more robust. 


Rapid deployment of technology
Prof Turton says this proof of concept is significant, because it took just eight weeks after reaching the agreement with KWR to find a laboratory with the necessary capabilities and to conduct the first tests. This is a rapid deployment of technology necessitated by the urgency of the COVID-19 pandemic. The source of funding for this demonstration was the private sector, so no taxpayer money was used. The proof of concept was deliberately designed to achieve two specific objectives. The main objective was to determine whether the Dutch methodology could be replicated in South Africa without major investment into training and procurement of laboratory equipment. The secondary objective was to understand the logistical complexities of sampling at multiple sewage works in one province, and then safely transporting those samples to the laboratory in another province. This emulates what will be needed if this methodology is adopted by government and rolled out across all provinces as required. 

Taking samples
Samples were taken over a 24-hour period using an automatic bulk sampler provided by a service provider at risk. A number of sewage works were sampled to emulate the complexity of a national operation should rapid implementation be required. The first samples were taken on Thursday 4 June. These were prepared according to a precise protocol and were shipped to the laboratory hundreds of kilometres away. The samples were prepared according to the stringent requirements of the protocol, and COVID-19 RNA was successfully extracted on Monday 8 June. Lessons learned in the first trial are being fed back to the team in preparation for the second sampling run that will take place shortly. 

Prof Turton, who serves in a facilitating role and in different capacities with each of the critical components of the overall value chain, is the man in the middle tying this whole process together. This is also a demonstration of the value of a university working in close collaboration with both government and private sector partners towards a common objective.  It is part of the Public Private Growth Initiative (PPGI), where the private sector works closely with the state to deliver core services needed to create employment opportunities as a matter of growing urgency.

Determining if the total viral load is increasing or decreasing
The second sampling run, which is about to be launched, will be a refinement of the first. Lessons learned during the logistical exercise will be applied to streamline the operation and generate an accurate costing of the service. By comparing the data for each sampling sequence, it will be possible to determine with a considerable degree of accuracy whether the total viral load in a given population is increasing or decreasing. When applied to multiple sewage works, it will be possible to identify hotspots for appropriate government intervention. This technical capability will provide robust information to both government and private sector decision-makers as they navigate their way through the complexity of a shutdown and phased re-opening of the national economy. Rapid upskilling of suitably qualified personnel will be needed, and the UFS will be playing a role in that process. 

News Archive

Twenty years of the constitution of South Africa – cause for celebration and reflection
2016-05-11

Description: Judge Azar Cachalia Tags: Judge Azar Cachalia

Judge Azar Cachalia

The University of the Free State’s Centre for Human Rights and the Faculty of Law held the celebration of the twentieth anniversary of the adoption of the South African Constitution on 11 May 2016 on the Bloemfontein Campus.  Students and faculty members celebrated and reflected on not only the achievements of the constitution but also on perspectives regarding its relevance in modern society, and to what extent it has upheld the human rights of all citizens of South Africa.

The panel discussion started with a presentation on the pre-1996 perspective by Judge Azar Cachalia of the Supreme Court of Appeal.  Judge Cachalia reflected on his role in the realisation and upholding of the constitution, from his days as a student activist, then as an attorney representing detainees during political turmoil, and currently as a judge: “My role as an attorney was to defend people arrested for public violence. My role as a judge today is to uphold the constitution.”  He stressed the importance of the constitution today, and the responsibility institutions such as the police service have in upholding human rights.  Judge Cachalia played a significant role in drafting the new Police Act around 1990, an Act which was to ensure that the offences perpetrated by the police during apartheid did not continue in the current democratic era. Further, he pointed out that societal turmoil has the potential to make society forget about the hard work that was put into structures upholding human rights. “Constitutions are drafted in moments of calm.  It is a living document, and we hope it is not torn up when we go through social conflict, such as we are experiencing at present.”

Thobeka Dywili, a Law student at the UFS, presented her views from the new generation’s perspective.  She relayed her experience as a student teaching human rights at schools in disadvantaged communities. She realised that, although the youth are quite aware of their basic human rights, after so many years of democracy, “women and children are still seen as previously disadvantaged when they should be equal”. She pointed out that, with the changing times, the constitution needs to be looked at with a new set of eyes, suggesting more robust youth engagement on topics that affect them, using technology to facilitate discussions. She said with the help of social media, it is possible for a simple discussion to become a revolution; #feesmustfall was a case in point.

Critical perspectives on the constitution were presented by Tsepo Madlingozi of University of Pretoria and University of London. In his view, the constitution has not affected policy to the extent that it should, with great disparities in our society and glaring issues, such as lack of housing for the majority of the poor.  “Celebration of the constitution should be muted, as the constitution is based on a decolonisation approach, and does not directly address the needs of the poor. The Constitutional Court is not pro-poor.”  He posed the question of whether twenty years on, the present government has crafted a new society successfully.  “We have moved from apartheid to neo-apartheid, as black elites assimilate into the white world, and the two worlds that exist have not been able to stand together as a reflection of what the constitution stands for.”

Prof Caroline Nicholson, Dean of the Faculty of Law, encouraged more open discussions, saying such dialogues are exactly what was intended by the Centre for Human Rights. She emphasised the importance of exchanging ideas, of allowing people to speak freely, and of sharing perspectives on important issues such as the constitution and human rights.

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