Publications 2017

Coetzee MJ, Blumberg LH, Paweska JT, Leman P, Swanepoel R, de Kock A. Crimean-Congo haemorrhagic fever presenting with undiagnosed chronic myeloid leukaemia. Southern African Journal of Infectious Diseases 2017. (Published online 01 Aug 2017. doi: 10.1080/23120053.2017.1345493).

Coetzee MJ, Joubert G, Swart M, Streicher A, Kruger M, Koekemoer H. An audit of the completion of bone marrow specimen request forms at an academic laboratory. Medical Technology SA 2017;31(1):1-6.

Janse van Rensburg WJ, Van der Merwe P. Comparison of Commercially Available Blood Collection Tubes Containing Sodium Citrate and Hirudin in Platelet Aggregation Testing. Medical Science Monitor Basic Research 2017;23:264-9.

Kloppers JF, Janse van Rensburg WJ. Rapid identification of the intron 22 inversion in haemophilia A. Haemophilia 2017;23:e55-e7. doi:10.1111/hae.13142 (Published online 08 December 2016).

Meiring M, Myneni S. Evaluation of a cost-effective ADAMTS 13 antigen assay. Medical Technology SA 2017;31:1-4.

Schochl H, van Griensven M, Heitmeier S, Laux V, Kipman U, Roodt J, Bahrami S, Redl H. Dual inhibition of thrombin and activated factor X attenuates disseminated intravascular coagulation and protects organ function in a baboon model of severe Gram-negative sepsis. Critical Care 2017;21:51.

Sreenivasan Tantuan S, du Plessis H, Stemmet M, Viljoen CD. Quantification of BCR-ABL1 on the GeneXpert: From diagnostics to research. Gene Reports 2017;8:107-9.

Tersteeg C, Roodt J, Van Rensburg WJ, et al. N-acetylcysteine in preclinical mouse and baboon models of thrombotic thrombocytopenic purpura. Blood 2017;129:1030-8.

Publications 2016

Coetzee M. Honesty is the best policy. Junior Doctor 2016;6(1):15

Favaloro EJ, Bonar RA, Mohammed S, Arbeleaz N, Niemann J, Freney R, Meiring M, Sioufi J, Marsden K. Type 2M Von Willebrand disease – more often misidentified than correctly identified. Haemophilia 2016;22(3):145-155

Haupt L, Weyers R. Determination of functional iron deficiency status in haemodialysis patients in central South Africa. International Journal of Laboratory Hematology 2016;38:352-9.

Janse van Rensburg WJ. Comparison of common platelet receptors between the chacma baboon (Papio ursinus) and human for use in pre-clinical human-targeted anti-platelet studies. Platelets 2016;27(4):322-32.

Meiring M, Allers W, Le Roux E. Tissue factor: A potent stimulator of Von Willebrand factor synthesis by human umbilical vein endothelial cells. International Journal of Medical Sciences 2016;13:759-64.

Weyers R, Coetzee MJ, Nel M. Iron status determination in pregnancy using the Thomas plot. International Journal of Laboratory Hematology 2016;38(2):119-24.

Publications 2015

Allie S, Stanley A, Bryer A, Meiring M, Combrinck MI. High levels of von Willebrand factor and low levels of its cleaving protease, ADAMTS13, are associated with stroke in young HIV-infected patients. International Journal of Stroke 2015;10(8):1294-6.

Coetzee M, Joubert J. Helpful hints for writing SI units. South African Medical Journal 2015;105:80.

Janse van Rensburg WJ, Badenhorst PN, Roodt JP. The Cape Chacma baboon is not suitable for evaluating human targeted anti-GPVI agents. Platelets 2015;26(6):552-7.

Kloppers JF, Janse van Rensburg WJ. Evaluation of a chromogenic factor VIII assay on the Sysmex CS 2100i instrument. Medical Technology SA 2015; 29(2): 27-30.

Publications 2014

Alli NA, Patel M, Alli HD, Bassa F, Coetzee MJ, Davidson A, Essop MR, Lakha A, Louw VJ, Novitzky N, Philip V, Poole JE, Wainwright R. Recommendations for the management of sickle cell disease in South Africa. South African Medical Journal 2014;104:743-51.

Favaloro EJ, Bonar R, Meiring M, Duncan E, Mohammed S, Sioufi J, Marsden K. Evaluation errors in the laboratory identification of van Willebrand disease in the real world. Thrombosis Research 2014;134:393-403.

Hayden Y, Pillay T, Marx G, de Lange W, Kuyl JM. Pre-analytical stability of 25(OH)-vitamin D in primary collection tubes. Clinical Chemistry and Laboratory Medicine 2014;53(3):e55-e57. doi:10.1515/cclm-2014-0543.

Joubert J, Joubert S, Raubenheimer J, Louw V. The long-term effects of training interventions on transfusion practice: A follow-up audit of red cell concentrate utilisation at Kimberley Hospital, South Africa. Transfusion and Apheresis Science 2014;51(3):25-32.

Joubert J, Weyers R, Raubenheimer J. Reducing unnecessary blood smear examinations: Can Sysmex blood cell analysers help? Medical Technology SA 2014;28(1):6-12.

Pretorius L, Janse van Rensburg WJ, Conradie C, Coetzee MJ. (2013), Minimum citrate tube fill volume for routine coagulation testing. International Journal of Laboratory Hematology 2014;36(4):493-5.

Publications 2013

Malan N, Von Kanel R, Schutte A, Huisman H. Smith W, Mels C, Kruger K, Meiring M, Van Rooyen J, Malan L. Testosterone and acute stress are associated with fibrinogen and von Willebrand factor in African men: The SABPA study. International Journal of Cardiology 2013;168(5):4638-4642.

Sreenivasan S and Viljoen CD. OCT1 identity crisis. Gene 2013;516(1):190-191.

Viljoen CD and Marx GM. The implications for mandatory GM labelling under the Consumer Protection Act in South Africa. Food Control 2013;31:387-391.

Viljoen CD, Synman MC and Spies JJ. Identification and expression analysis of chalcone synthase and dihydraflavonol 4-reductase in Clivia minuta. South African Journal of Botany 2013;87:18-21.

Viljoen CD. 2013. Letter to the Editor. Food and Chemical Toxicology 59: 809-810.

Viljoen, CD, Thompson GG and Sreenivasan S. Stability of ultramer as copy number standards in real-time PCR. Gene 2013;516:143-145.

Von Kanel R, Hamer M, Malan N, Scheepers K, Meiring M, Malan L. Procoagulant reactivity to laboratory acute mental stress in Africans and Caucasians and its relation to depressive symptom: The SABPA Study. Thrombosis and Haemostasis 2013;110(5):977 -986.

Publications 2012

Botma J, Mogongoa LF, Jafta AD, Janse van Rensburg WJ. Reference ranges for platelet indices using Sysmex XE-2100 blood analyser. Medical Technology SA 2012; 26(2):17-21.

Callewaert F, Roodt J, Ulrichts H, Stohr T, van Rensburg WJ, Lamprecht S, Rossenu S, Priem S, Willems W, Holz JB. Evaluation of efficacy and safety of the anti-VWF Nanobody ALX-0681 in a preclinical baboon model of acquired thrombotic thrombocytopenic purpura. Blood 2012;120(17):3603-3610.

Favaloro EJ, Bonar R, Chapman K, Meiring M, Funk Adcock D. Differential sensitivity of von Willebrand factor (VWF) activity assays to large and small VWF molecular weight forms: a cross-laboratory study comparing ristocetin cofactor, collagen-binding and mAb-based assays. Journal of Thrombosis and Haemostasis 2012;10:1043–54.

Feys HB, Roodt J, Vandeputte N, Pareyn I, Mottl H, Hou S, Lamprecht S, Van Rensburg WJ, Deckmyn H, Vanhoorelbeke K. Inhibition of von Willebrand factor-platelet glycoprotein Ib interaction prevents and reverses symptoms of acute acquired thrombotic thrombocytopenic purpura in baboons. Blood 2012;120(17):3611-4.

Joubert J, Badenhorst PN, Conradie C. An Audit of Coagulation Specimens Requiring Direct Human Involvement at an Academic Laboratory. Medical Technology SA 2012; 26(1):44-47.

Mahlangu JN, Coetzee MJ, Laffan M, Windyga J, Yee TT, Schroeder J, Henning J, Siegel JE and Lemm G.  Phase I randomized, double-blind, placebo-controlled, single-dose escalation study of the recombinant factor VIIa variant BAY 86-6150 in haemophilia. Journal of Thrombosis and Haemostasis 2012;10(5):773-780.

Meiring SM, Webb M, Goedhals D, Louw V.  HIV associated Thrombotic Thrombocytopenic Purpura – What we know so far? European Oncology and Haematology 2012; 8(2):89-91.

Thibane VS, Ells R, Hugo A, Albertyn J, van Rensburg WJ, Van Wyk PW, Kock JL, Pohl CH. Polyunsaturated fatty acids cause apoptosis in C. albicans and C. dubliniensis biofilms.
Biochimica et Biophysica Acta 2012;1820(10):1463-8.

Van Rensburg WJ, Roodt JP, Lamprecht S, Meiring SM, Badenhorst PN. Tirofiban versus abciximab: tirofiban is administered at suboptimal dosages when evaluated in an arterial thrombosis model in non-human primates. Clinical and Experimental Medicine 2012; 12(4):257-263.

Viljoen CD. 2012. Mandatory labeling of genetically modified food in South Africa: What you should know? South African Association for Food Science and Technology. November issue: 36-37.

Webb MJ, Jafta D. Imatinib Use in Pregnancy. Turkish Journal of Hematology 2012; 29: 405–408.

Publications 2011

Coetzee MJ. Inappropriate delegation. United Kingdom Casebook 2011;19(2):24. (published by the Medical Protection Society ISSN 1366 4409. available on

Meiring M, Coetzee M, Kelderman M, Badenhorst P. Laboratory diagnosis and management of von Willebrand disease in South Africa. Seminars in Thrombosis and Hemostasis 2011; 37(5):576-80.

Ulrichts H, Silence K, Schoolmeester A, de Jaegere P, Rossenu S, Roodt J, Priem S, Lauwereys M, Casteels P, Van Bockstaele F, Verschueren K, Stanssens P, Baumeister J, Holz JB. Antithrombotic drug candidate ALX-0081 shows superior preclinical efficacy and safety compared with currently marketed antiplatelet drugs. Blood 2011;118(3):757-65.

Viljoen CD and Chetty. A case study of GM maize gene flow in South Africa. Environmental Sciences Europe 2011;23:1-8.

Viljoen CD. "Genetic labeling" claims wrong. BusinessDay online 03 February 2011 (accessed 13 February 2012).

Wilson JC, De Kock A, Weyers R, Louw V. Triple heterozygous thrombophilic mutations: a family study. Medical Technology SA 2011; 25(2):36-39.

Publications 2010

Chen W, Leiter A, Dong Y, Meiring M, Louw V, Koeffler P. Curcurbitan B inhibits growth, arrest the cell cycle and potentiates antiproliferative efficacy of cisplatin in cutaneous squamous cell carcinoma cell lines. International Journal of Oncology 2010;37(3):737-743.

Coetzee MJ. Coetzee MJ. Clinical haematologists competent in the laboratory and at the bedside. South African Medical Journal 2010;100(9):544-545.

Feys HB, Roodt J, Vandeputte N, Pareyn I, Lamprecht S, van Rensburg WJ, Anderson PJ, Budde U, Louw VJ, Badenhorst PN, Deckmyn H, Vanhoorelbeke K. Thrombotic thrombocytopenic purpura directly linked with ADAMTS13 inhibition in the baboon (Papio ursinus). Blood 2010;116(12):2005-10.

Jafta AD, Meiring SM, Conradie C. Valproic acid associated platelet dysfunction: Case Report. African Journal of Haematology and Oncology 2010;1(2):15.

Viljoen, C.D., Chetty, L. 2010. Chapter 2: An African perpsective of GM maize gene flow. Theorie in der Ökologie, Band 16 in: Breckling, B., Verhoeven, R. (eds.): Large-area effects of GM-crop cultivation, pp. 60-61. ISBN 978-3-631-60361-1.

Publications 2009

Botha GM, Viljoen CD. South Africa: A case study for voluntary GM Labelling. Food Chemistry 2009;112(4):1060-1064.

Coetzee MJ, Louw VJ, Gartrell K, Viljoen CD. Chakalaka-induced vasodilatation in patients with chronic myeloid leukaemia on tyrosine kinase inhibitors. South African Medical Journal 2009;99(12):870-871.

Favaloro EJ, Thom J, Patterson D, Just S, Baccala M, Dixon T, Meiring SM, Koutts J, Rowell J, Baker R. Potential supplementary utility of combined PFA-100 a functional VWF testing for the laboratory assessment of desmopressin and factor concentrate therapy in von Willebrand disease. Blood Coagulation and Fibrinolysis 2009;20(6):475-483.

Jacquemin M, Stassen JM, Saint-Remy JM, Verhamme P, Lavend'homme R, VanderElst L, Meiring M, Pieters H, Lamprecht S, Roodt J, Badenhorst P. A human monoclonal. antibody inhibiting partially factor VIII activity reduces thrombus growth in baboons. Journal of Thrombosis and Haemostasis 2009;7(3):429-37.

Meiring SM, Kelderman M, Badenhorst PN. Laboratory diagnosis of Von Willebrand Disease. European Haematology 2009;3(1): 33-36.

Meiring SM, Vermeulen J, Badenhorst PN. Development and Functional Characterisation of an Inhibitory Antibody Fragment to Human Tissue Factor. Drug Development Research 2009;70:199-205.


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