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25 April 2019 | Story Rulanzen Martin | Photo Jolandi Griesel
Dr Whitty Green, Dr Engela van Staden and Prof Francois Strydom
Dr Whitty Green, Dr Engela van Staden and Prof Francois Strydom, Senior Director of CTL.

Data, quality, and capacity building were among the main topics of discussion at the third annual Teaching and Learning Conference hosted by the Centre for Teaching and Learning at the University of the Free State (UFS).

Dr Engela van Staden, Vice-Rector: Academic, welcomed delegates on the first day of the conference. The three themes of the conference were quality, capacity and excellence. “These three constructs have never been more relevant in South African higher education than now,’ said Dr Van Staden. “The quality of education, globally, and specifically in SA, is being questioned. Both public and private sectors are demanding graduates that need to meet the challenges of the 21st Century.” 

The aim of the teaching and learning conference is to foster more collaboration between academics at the UFS. A total of 14 academics from across all seven faculties presented during the two-day conference. Dr Whitty Green from the Department of Higher Education and Training (DHET) delivered the keynote on the first day and Prof Corlia Janse van Vuuren delivered the second day keynote.

The inclusion of technology in the world of work and the use of data analytics are fundamentally confronting our learning and teaching place. “And I hope some of the issues will be addressed in the presentations,” Dr Van Staden said. 

Bringing down silos of research and teaching

Dr Green spoke about the Enacting the National Framework for Enhancing Academics as University Teachers. “Academics are teachers and researchers and they have to engage with the community. There are multiple roles and these roles intersect,” Dr Green said. In order to build capacity in the system it is important to understand the multiple natures of the roles and try to work with them. This is the reason why the teaching development grant and teaching grant have been pulled together to form the University Capacity Grant. “We are trying to break down the silos of research development and teaching development at universities,” he said.

Prof Janse van Vuuren, Head of the UFS School of Allied Health Professionals, delivered her keynote address on Quality, Capacity and Excellence: Dotting the Is and crossing the Ts in a changing, data-driven Higher Education Environment. She shared her story to establish a faculty-based operational framework for teaching and learning.

“I did not know how to bring all of the issues ranging from research, teaching and learning and student success into one framework,” said Prof Janse van Vuuren. She developed a faculty-based operational framework for teaching and learning for the Faculty of Economic and Management Sciences.

The third annual UFS Teaching and Learning Conference took place from 26 to 27 March 2019.



News Archive

UFS study on cell development in top international science journal
2008-09-16

A study from the University of the Free State (UFS) on how the change in the packaging of DNA with cell development influenced the expression of genes, will be published in this week’s early edition of the prestigious international, peer-reviewed science journal, the Proceeding of the National Academy of Sciences of the USA (PNAS).

The PNAS journal has an impact factor of 10, which means that studies published in the journal are, on average, referred to by ten other scientific studies in a two year period. The South African Journal of Science, by comparison, has an impact factor of 0.7.

The UFS study, funded by the Wellcome Trust and the National Research Foundation (NRF), looked at how the change in the packaging of DNA with cell development influenced the expression of genes. It is very relevant to research on stem cells, an area of medicine that studies the possible use of undifferentiated cells to replace damaged tissue.

Prof. Hugh Patterton, of the Department of Microbial, Biochemical and Food Biotechnology at the UFS, who led the study, said: "We are extremely proud of this study. It was conceived in South Africa, it was performed in South Africa, the data were analysed in South Africa, and it was published from South Africa."

When a gene is expressed, the information encoded in the gene is used to manufacture a specific protein. In eukaryotes, which include humans, there is approximately 1m of DNA, containing the genes, in every cell. This length of DNA has to fit into a cell nucleus with a diameter of only about 10 micrometer. In order to fit the DNA into such a small volume, eukaryotic cells wrap their DNA onto successive protein balls, termed nucleosomes. Strings of nucleosomes, resembling a bead of pearls, is folded into a helix to form a chromatin fiber. The study from the UFS investigated how the binding of a specific protein, termed a linker histone, that binds to the length of DNA between nucleosomes, influenced the formation of the chromatin fiber and also the activity of genes.

"We found that the linker histone bound to chromatin in yeast, which we use as a model eukaryote, under conditions where virtually all the genes in the organism were inactive. It was widely believed that the binding of the linker histone caused the inactivation of genes. We studied the relationship between the amount of linker histone bound in the vicinity of each gene and the expression of that gene for all the genes in yeast, using genomic techniques. We made the surprising discovery that even through the linker histone preferentially bound to genes under conditions where the genes were shut off, this inactivation of genes was not caused by the binding of the linker histone and folding of the chromatin,” said Prof. Patterton.

He said: “Instead our data strongly suggested that the observed anti-correlation was due to the movement of enzymes along the DNA molecule, involved in processing the information in genes for the eventual manufacture of proteins. This movement of enzymes displaced the linker histones from the DNA. This finding now requires a rethink on aspects of how packaging of DNA influences gene activity."

Prof. Patterton said that his research group, using the Facility for Genomics and Proteomics as well as the Bioinformatics Node at the UFS, was currently busy with follow-up studies to understand how other proteins in nucleosomes affected the activities of genes, as well as with projects to understand how chemicals found in red wine and in green tea extended lifespan. "We are certainly having a marvelous time trying to understand the fundamental mechanisms of life, and the UFS is an exciting place to be if one was interested in studying life at the level of molecules," he said.


Media Release
Issued by: Lacea Loader
Assistant Director: Media Liaison
Tel: 051 401 2584
Cell: 083 645 2454
E-mail: loaderl.stg@ufs.ac.za  
18 September 2008
 

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