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18 April 2019 | Story Leonie Bolleurs | Photo Sonia Small
First Lady Visit
At a gathering with the First Lady and UFS management were, from the left: Prof Prakash Naidoo, Vice-Rector: Operations; Prof Maléne Campbell; Chacha; Dr Tshepo Motsepe, First Lady of South Africa; Prof Petersen; Prof Puleng Lenka-Bula; Vice-Rector: Institutional Change, Student Affairs, and Community Engagement; and Prof Danie Vermeulen, Dean of the Faculty of Natural and Agricultural Sciences.

“I am from a very small town called Marquard. I am a granny’s boy – who was a domestic worker – and can speak fluent Afrikaans. I am fearless and I understand my calling for greatness. I stand and advocate for social justice and I am not scared to challenge any form of injustice. I hate people who abuse power and I am no friend of mediocrity. I speak my mind.”

This and much more describes Thapelo Chacha, a graduate in the Department of Urban and Regional Planning, who received his Honours degree in Spatial Planning at the recent April graduation ceremonies of the University of the Free State (UFS). 

The First Lady

He is also the student who brought Dr Tshepo Motsepe, the First Lady of South Africa to Kovsies. 

Chacha tells his story: “I met the First Lady some years back through Dr Vuyelwa Manzana, who was my mother’s doctor at the time – after dropping out of university due to a financial crisis. I was handed over to the lawyers, with a debt that accrued over three years. I knocked at every door you can think of – with no luck. One day I got a call from a lady who introduced herself as Mme Tshepo, asking me to go to university. I laughed, because I knew my debt was too big to allow me to study again. She insisted, and when I arrived at the UFS, my outstanding debt had been paid and I was able to register. The same Mme Tshepo called to assure me that she will pay for my tuition, meals, books, and accommodation. I did not even know that she was the wife of Mr Cyril Ramaphosa, who would later become the Deputy President and now the President of the country.”

“Mme Tshepo sponsored me from her own pocket until I became part of the Cyril Ramaphosa Education Trust (CRET).”

“She personally texted and called me about my graduation information so she could attend. You can imagine the excitement and the shock. Although I have met the First Lady many times, it will be the first time that I will introduce her to my family. She is taking me and my family – my mother and my grandmother – to lunch after the ceremony. I see that as a favour of God upon my life.”

Prof Francis Petersen, UFS Rector and Vice-Chancellor at a meeting with Dr Motsepe and Chacha said: “Access to university is crucial. However, we would also like our students to exit with a qualification. This is how a bursary like this one from CRET helps. We would like to exit students that contribute to the economy.”

Making a difference

Chacha is now doing his master’s in Urban and Regional Planning. “I am so looking forward to registering with the South African Council for Planners (SACPLAN) as a professional town planner at the end of my master’s degree within a few months. 

“I see myself joining a town planning division anywhere in South Africa, dedicated to changing the living conditions of ordinary citizens. Spatial planning speaks to the heart of land use and ensures that the land is used and occupied in a manner that is beneficial to everyone who needs it,” Chacha said. 

He believes town planning has been largely influenced by politics, thus forcing town planners to move away from serving the needs of the ordinary citizen. Chacha would like to see the injustices of the past, especially with regard to townships, being addressed. “This is why my dissertation is about township infrastructure and the contribution it makes towards township economy.”

“I would like to see a South Africa that is centred on the well-being of its citizens. The older generation has fought the brutality of apartheid; our battle as the youth is to be academically equipped to fight and win the land battle,” he said.

Kovsie encounters

For Chacha, his studies in Urban and Regional Planning was very tough. But the support he received from his lecturers was immeasurable. “Prof Maléne Campbell, Head of the UFS Department of Urban and Regional Planning has the most competent team. This is the best department on campus, with no racial issues or unpleasant vibes. I just love the space.”

“The UFS has taught me resilience, hard work, the importance of networking, and the knowledge that you need to be radical when it comes to your future,” Chacha concluded.

News Archive

Cardiology Unit involved in evaluation of drug for rare genetic disease
2013-01-04

Front from the left, are: Marinda Karsten (study coordinator and registered nurse),
Laumarie de Wet (clinical technologist), Charmaine Krahenbuhl (study coordinator and radiographer),
Lorinda de Meyer (administrator), Andonia Page (study coordinator and enrolled nurse);
back Dr Gideon Visagie (sub investigator), Dr Derick Aucamp (sub investigagtor),
Prof. Hennie Theron, (principal investigator) and Dr Wilhelm Herbst (sub investigator).
Photo: Supplied
09 January 2013


The Cardiology Research Unit at the University of the Free State (UFS) contributed largely to the evaluation of the drug Juxtapid (lomitapide), which was developed by the Aegerion pharmaceutical company and approved by the FDA (Federal Drug Administration). Together with countries such as die USA, Canada and Italy, the UFS’ Unit recruited and evaluated the most patients (5 of 29) for the study since 2008.  

The drug was evaluated in persons with so-called familial homozygous hypercholesterolemia (HoFH).  

Following its approval by the FDA, Juxtapid is now a new treatment option for patients suffering from HoFH. The drug operates in a unique way which brings about dramatic improvements in cholesterol counts.  

According to Prof. Hennie Theron, Associate Professor in the Department of Cardiology at the UFS and Head of the Cardiology Contract Research Unit, HoFH is a serious, rare genetic disease which affects the function of the receptor responsible for the removal of low-density lipoprotein cholesterol (LDL-C) (“bad” cholesterol) from the body. Damage to the LDL receptor function leads to extremely high levels of blood cholesterol. HoFH patients often develop premature and progressive atherosclerosis, which is a narrowing or blockage of the arteries.  

“HoFH is a genetically transmitted disease and the most severe form of hypercholesterolemia. Patients often need a coronary artery bypass or/and aortic valve replacement before the age of 20. Mortality is extremely high and death often occurs before the third decade of life. Existing conventional cholesterol-lowering medication is unsuccessful in achieving normal target cholesterol values in this group of patients.  

“The only modality for treatment is plasmapheresis (similar to dialysis in patients with renal failure). Even with this type of therapy the results are relatively unsatisfactory because it is very expensive and the plasmapheresis has to be performed on a regular basis.  

“The drug Juxtapid, as currently evaluated, has led to a dramatic reduction in cholesterol values and normal values were achieved in several people. No existing drug is nearly as effective.  

“The drug represents a breakthrough in the treatment of familial homozygous hypercholesterolemia. The fact that it has been approved by the FDA, gives further impetus to the findings,” says Prof. Theron.  

In future further evaluation will be performed in other forms of hypocholesterolemia.  

According to Prof. Theron, the findings of the study, as well as the recent successful FDA evaluation, once again confirms the fact that the UFS’ Cardiology Contract Research Unit is doing outstanding work.  

Since its inception in 1992, the Unit has already been involved in more than 60 multi-centre, international phase 2 and 3 drug studies. Several of these studies, including the abovementioned study, really affected the way in which cardiology functions.  

The UFS’ Cardiology Contract Research Unit is being recognised nationally and internationally for its high quality of work and is constantly approached for their involvement in new studies.  

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