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18 April 2019 | Story Eugene Seegers | Photo Stephen Collett
Prof Chris Hermans
Prof Chris Hermans, extraordinary professor at the UFS, presents his inaugural lecture, titled Theology in an Age of Contingency.

“The road ahead is empty / It’s paved with miles of the unknown.”

Prof Chris Hermans quoted these lines from the song The Road Ahead, by Dutch vocal group City to City to introduce his inaugural lecture in the Faculty of Theology and Religion on 27 February 2019. Prof Hermans, a veteran researcher in pastoral theology, empirical, and practical religious studies at the Radboud University Nijmegen in the Netherlands and an extraordinary professor at the UFS, chose as his theme Theology in the Age of Contingency, stating that the uncertainty of life has affected all disciplines in the academy, from the sciences, philosophy, and pedagogy, to theology itself.

Although contingency is often defined as a “future event ... which is possible but cannot be predicted with certainty” (Oxford English Dictionary), Prof Hermans stated that, in the context of theology, it has more to do with complexity, unpredictability, coexistence of cultures, and an increasing number of decisions people need to make in modern-day life. 

Changing lanes

Prof Hermans recounted a memory from his childhood to illustrate some aspects of contingency: “Growing up, my parents told me to cycle on the right side of the road. They knew what the right side was. Everything had a right side: What norms and values to live by, what was right or wrong, when to pray and which words to use. ... We now live in a different world.”

Prof Hermans’ inaugural lecture reflected on four tasks of practical theology and missiology. He further asserted that the content and aim of these tasks change from the perspective of contingency.

Contingency perspectives

From a sociological perspective, said Prof Hermans, contingency is a characteristic of the age of modernisation in which we live. He stated that in the modern age, people have a much greater choice of individual ‘action options’ as well as a growing number of experiences as a result. Expounding on this, he said, “The fact that I am a Christian, and another person Hindu or Muslim, is largely due to the fact that I was born within a Christian family. The fact that I am Christian is a possibility and an actuality, but not a necessity.”

Prof Hermans also helped listeners to understand other areas in which contingency plays a role, such as the binary logic used when determining modalities of truth, or changing world views and philosophies of being, or even in our ethos, our art of living, and outlook on life.

News Archive

Nuclear Medicine on the forefront of cancer research
2017-07-10

Description: Nuclear Medicine on the forefront of cancer research Tags: Nuclear Medicine, cancer research, Dr Je’nine Horn-Lodewyk’s, tumour detection method, cancer, Department of Nuclear Medicine 

Dr Je’nine Horn-Lodewyk’s tumour detection method
could be the cost-effective breakthrough needed to decrease
the mortality rate in breast cancer patients.
Photo: Anja Aucamp

The field of Nuclear Medicine in South Africa and the rest of the world are expanding rapidly due to the development of hybrid cameras and new radiopharmaceuticals. These developments have a huge impact on the diagnosis and therapy of cancer.

The most advanced of these cameras, Positron emission tomography combined with normal CTs (PETCT), are not yet widely available in South Africa due to the cost of the cameras and the radiopharmaceuticals. A more cost-effective alternative can be of great benefit. To achieve this, the focus should be on developing new radiopharmaceuticals that can be used with the current cost-effective gamma cameras, according to University of the Free State researcher, Dr Je’nine Horn-Lodewyk from the Department of Nuclear Medicine.

Fluorodeoxyglucose (18F-FDG), a radiolabelled glucose analogue, is currently the radiopharmaceutical most commonly used in PET/CT imaging for mainly oncology indications. Although it is considered the gold standard for imaging in several malignancies, it does have certain disadvantages. An 18F-FDG PET/CT diagnostic imaging study can cost between R25 000 and R35 000 for a single patient in the private sector. The 18F-FDG is also more radioactive, which requires much stricter handling and shielding to avoid high radiation dosages to staff and patients.

Successful research potential innovative solution
In the search for the ideal radiopharmaceutical for tumour detection, the South African National Nuclear Energy Corporation (Necsa) developed a local synthesis process for ethylenedicysteine-deoxyglucose (EC-DG). EC-DG is also a glucose analogue similar to FDG. They succeeded in labelling the compound with Technetium-99-metastable-pertechnetate (99mTcO4-), the most common nuclear medicine isotope used for approximately 95% of nuclear medicine procedures, creating 99mTc-EC-DG.

In partnership with Dr Horn-Lodewyk, this compound was successfully used in various animal models and clinical scenarios, resulting in approval by the Medicine Control Council to use it in a human study. Research is also planned in order to investigate diagnostic accuracy in other cancers like lymphoma.  The end result of this research can produce a radiopharmaceutical that is cost effective, does not require the use of costly specialised equipment, has no significant side-effects, no special patient preparation, renders late imaging possible, and has decreased radiation risks.

Dr Horn-Lodewyk is grateful for the support of her mentor, Prof Anton Otto, as well as Dr Gert Engelbrecht, Head of the Department of Nuclear Medicine, Prof Jan Rijn Zeevaart from North-West University’s Preclinical Drug Development Platform and Necsa, and Judith Wagener from Necsa. This innovative research would also not have been possible without the financial assistance of Dr Glen Taylor and Eleanor van der Westhuizen in the Directorate of Research Development.

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