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Two Kovsies in Entrepreneurship Intervarsity finals

19 August 2019 | Story Charlene Stanley | Photo Ayanda Makhanya

A natural heating and cooking system and liquid yeast in its purest form – used in the brewing of beer – form the basis of two innovative business ventures that have earned their inventors a place in the finals of this year’s Entrepreneurship Intervarsity.

LiquidCulture

Christopher Rothman is currently busy with his PhD in Biotechnology at the Department of Microbial, Biochemical and Food Biotechnology at the University of the Free State (UFS). He and a fellow student started the company LiquidCulture last year to make high-quality yeast for their own commercial brewery called Kraft Brewing Co.

“We realised that because of our backgrounds as microbiologists, we could grow our own yeast, have a better quality product, and save some money while also expanding our choice of yeast strains to use. This quickly became more than a solution to our own problems, as other breweries were also interested in using our yeast. We then formed LiquidCulture and started supplying the industry,” says Christopher.

Organic Heat

Grace Mthembu’s inspiration for her eco-friendly, cost-effective heating and cooking device, came after reading about devastating fires in rural and informal settlements caused by cooking fires.

“I decided to investigate the cause of these fires and found that the majority of the households did not have access to electricity or they couldn’t afford it,” explains Grace.
Her invention is based on the traditional metal cylinder or “imbawula”, used by many households in informal settlements to cook or heat with wood or coal. What makes her invention different is that it has a water filtration interior system which makes it safer and ensures that the smoke produced during the heating of the sources does not get released into the home and the air in general.

Her invention has already earned her awards for best community development, best mechanical engineering and best rural development project in the Eskom Expo for Young Scientists, plus a gold medal and all-expenses-paid trip to represent South Africa at the London International Youth Science Fair.
She plans to establish a brand for the system with the name “Organic Heat”.

Student entrepreneurs showcased

The Entrepreneurship Intervarsity gives student entrepreneurs from across the country’s 26 public universities the opportunity to submit their innovative ideas as part of a competition supported by Entrepreneurship Development in Higher Education (EDHE), in collaboration with the Allan Gray Orbis Foundation.
Both Christopher and Grace see it as a great honour to represent the UFS in the finals, which will be held in Johannesburg on 18 September 2019.

“The intervarsity has been fun thus far and the quality of the competitors is really high. Luckily I like public speaking and I am really passionate about my company so pitching to the judges has been very comfortable for me so far,” says Christopher.

“I’m not obsessed about winning,” says Grace. “I’m looking forward to networking and connecting and building relationships with potential investors. If I do happen to win, it will obviously be amazing and will provide me with a lot of exposure and bring opportunities.”

News Archive

Nuclear Medicine on the forefront of cancer research

2017-07-10

Dr Je’nine Horn-Lodewyk’s tumour detection method
could be the cost-effective breakthrough needed to decrease
the mortality rate in breast cancer patients.
Photo: Anja Aucamp

The field of Nuclear Medicine in South Africa and the rest of the world are expanding rapidly due to the development of hybrid cameras and new radiopharmaceuticals. These developments have a huge impact on the diagnosis and therapy of cancer.

The most advanced of these cameras, Positron emission tomography combined with normal CTs (PETCT), are not yet widely available in South Africa due to the cost of the cameras and the radiopharmaceuticals. A more cost-effective alternative can be of great benefit. To achieve this, the focus should be on developing new radiopharmaceuticals that can be used with the current cost-effective gamma cameras, according to University of the Free State researcher, Dr Je’nine Horn-Lodewyk from the Department of Nuclear Medicine.

Fluorodeoxyglucose (18F-FDG), a radiolabelled glucose analogue, is currently the radiopharmaceutical most commonly used in PET/CT imaging for mainly oncology indications. Although it is considered the gold standard for imaging in several malignancies, it does have certain disadvantages. An 18F-FDG PET/CT diagnostic imaging study can cost between R25 000 and R35 000 for a single patient in the private sector. The 18F-FDG is also more radioactive, which requires much stricter handling and shielding to avoid high radiation dosages to staff and patients.

Successful research potential innovative solution
In the search for the ideal radiopharmaceutical for tumour detection, the South African National Nuclear Energy Corporation (Necsa) developed a local synthesis process for ethylenedicysteine-deoxyglucose (EC-DG). EC-DG is also a glucose analogue similar to FDG. They succeeded in labelling the compound with Technetium-99-metastable-pertechnetate (99mTcO4-), the most common nuclear medicine isotope used for approximately 95% of nuclear medicine procedures, creating 99mTc-EC-DG.

In partnership with Dr Horn-Lodewyk, this compound was successfully used in various animal models and clinical scenarios, resulting in approval by the Medicine Control Council to use it in a human study. Research is also planned in order to investigate diagnostic accuracy in other cancers like lymphoma. The end result of this research can produce a radiopharmaceutical that is cost effective, does not require the use of costly specialised equipment, has no significant side-effects, no special patient preparation, renders late imaging possible, and has decreased radiation risks.

Dr Horn-Lodewyk is grateful for the support of her mentor, Prof Anton Otto, as well as Dr Gert Engelbrecht, Head of the Department of Nuclear Medicine, Prof Jan Rijn Zeevaart from North-West University’s Preclinical Drug Development Platform and Necsa, and Judith Wagener from Necsa. This innovative research would also not have been possible without the financial assistance of Dr Glen Taylor and Eleanor van der Westhuizen in the Directorate of Research Development.

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