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22 August 2019 | Story Zama Feni | Photo Charl Devenish
Innocentia working in the lab
UFS academic, Innocensia Mangoato, doing her work in the laboratory.


Born as the only girl among boys in the Tanzanian capital city of Dar es Salaam in 1992, the University of the Free State (UFS) academic Innocensia Mangoato says she feels inspired by women who strive to break the barricades of patriarchy.

“I am inspired by resilient women who are able to overcome everyday challenges, even in a world that treats men as superiors,” she says.

At the tender age of 27, Mangoato has achieved more than many of her peers. Last year, she won a Women in Science Award (WISA) for her research on the use of cannabis in cancer treatment.  She is now a Doctor of Philosophy (PhD) candidate in Pharmacology and also a researcher and lecturer in the Department of Pharmacology – a job she started in May this year.

Early years

Mangoate’s dad was in exile at the ANC base camp outside Morogoro in Tanzania and met her Tanzanian mother during his stay there; she returned with her parents to South Africa in 1994, as political organisations were already unbanned at that time.

One of the factors that Mangoate attributes her academic success to, is her parents. “Both my parents valued education, and I believe this greatly contributed to my development. Coming from a rural upbringing, one of the lessons I learned is that perseverance and hard work always pay off.”

On her navigation of life – trying to determine what exactly could mould her to become what she wanted to be, Mangoate hailed her father as her pillar of strength. “When the going gets tough, my father has always been there to remind me to “keep on keeping on, no matter how hard it may be, because there’s always victory on the other side.”

Academic success

Mangoate obtained her master’s in Pharmacology at the UFS June 2019 graduation ceremony, one month before South Africa celebrates Women’s Month. She brands herself as “a representative of all women in science” and is enjoying empowering young scientists through lecturing and research at the university.

Asked about what nobody else knows about her, Mangoate hesitated for a moment and then beamed, “I am an academic at heart.” There is no doubt about this, as her academic achievements really attest to that.

On how she envisions the UFS in future, especially with regard to women’s issues, she boldly states: “More women will be running departmental affairs, working towards progressive change within the UFS for both the academics and other programmes.”

She interprets success as something that is measured by happiness, being able to help other people reach their goals, and the ability to achieve all one wishes for, while making sure that it’s both impactful and beneficial to others.

Mangoate’s advice to other would-be academic achievers is that they should be focused and determined when it comes to achieving their goals, working diligently in everything they do, “irrespective of whether you like it or not”.

“Being the only girl among boys has taught me to always strive to be better than myself and not to compete with anyone,” says Mangoate.

“Just show up and give it your all.”

News Archive

Newly operational sequencing unit in genomics at UFS
2016-09-09

Description: Next Generation Sequencing  Tags: Next Generation Sequencing

Dr Martin Nyaga and his research assistant,
Tshidiso Mogotsi in the Next Generation
Sequencing Laboratory.
Photo: Charl Devenish

The Next Generation Sequencing (NGS) unit at the UFS was established as an interdisciplinary facility under the Directorate for Research Development, Faculty of Health Sciences and Faculty of Natural and Agricultural Sciences.

The aim of the NGS facility is to aid internal and external investigators undertaking studies on Deoxyribonucleic acid (DNA) sequencing, assembly and bioinformatics approaches using the more advanced Illumina MiSeq NGS platform.

The NGS unit became operational in 2016 and is managed by Dr Martin Nyaga and administered through the office of the Dean, Faculty of Health Sciences, under the leadership of Prof Gert Van Zyl. Dr Nyaga has vast experience in microbial genomics, having done his PhD in Molecular Virology.

He has worked and collaborated with globally recognised centres of excellence in Prokaryotic and Eukaryotic genomics, namely the J. Craig Venter Institute and the Laboratory of Viral Metagenomics, Rega Institute, among others.

The unit has undertaken several projects and successfully generated data on bacterial, viral and human genomes. Currently, work is ongoing on bacterial and fungal metagenomics studies through 16S rRNA sequencing.

In addition, the unit is also working on plasmid/insert sequencing and whole genome sequencing of animal and human rotaviruses. The unit has capacity to undertake other kinds of panels like the HLA, Pan-cancer and Tumor 15 sequencing, among others.

Several investigators from the UFS including but not limited to Prof Felicity Burt, Prof Wijnand Swart, Dr Frans O’Neil, Dr Trudi O'Neill, Dr Charlotte Boucher, Dr Marieka Gryzenhout and Dr Kamaldeen Baba are actively in collaboration with the NGS unit.

The unit has also invested in other specialised equipment such as the M220 Focused-ultrasonicator (Covaris), 2100 Bioanalyzer system (Agilent) and the real-time PCR cycler, the Rotor-Gene Q (Qiagen), which both the UFS and external investigators can use for their research.

Investigators working on molecular and related studies are encouraged to engage with Dr Nyaga on how they would like to approach their genomics projects at the UFS NGS unit. 

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