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06 December 2019 | Story Valentino Ndaba | Photo Supplied
Stephan Diedericks
Pictured is an overall view of the re-appropriated taxi terminal model by Stephan Diedericks, winner of the 2019 Corobrik Regional Student of the Year Award.

If all works out, Kovsie student Stephan Diedericks could change the face of the Mangaung Metropolitan Muncipality’s transportation facilities and save the city millions in maintenance costs while generating income.

The Masters Architecture graduate designed an innovative model titled An Interminable Living Machine: Humanizing and Re-appropriating the dormant Mangaung Intermodal Transport Facility (MITF) into a living, economic systems of change which won him the Corobrik Regional Student of the Year Award. The awards ceremony was hosted by the UFS Department of Architecture on 22 November 2019 at the Bloemfontein Campus.

A living machine

Re-appropriating the Bloemfontein taxi terminal located in the Central Business District (CBD) which has been non-operational for a few years would mean that the building sustained itself, and acted a power generator both environmentally and economically. 

Diedericks was inspired by the need to improve the quality of life for the people of City of Roses. “This course helped to broaden my perspective on the power of architecture and the social change that it can bring to people's lives,” he said.

An environmentally-friendly concept

According to the young architect, the facility would be water efficient. “Bloemspruit channels run underneath the proposed site and water will be filtered through biologically that will provide water to the entire site creating a self-sufficient living building with water at its heart.”

A thriving economic hub

Diedrick’s 220-page thesis details how the site of the intervention was once home to Bloemfontein’s first power station and that it is this concept of power generation that led him to place clients at the centre of the project as a catalyst for change.  

“The Small, Medium and Micro Enterprise Business (SMME) division of the Free State Department of Economic, Small Business Development, Tourism and Environmental Affairs (DESTEA) serves as the catalyst and a power generator that breaks open the solid mass of the MITF. Several subsystems, including aquaponics and SMME training, feed of the main catalyst and in turn provide resources in the form of food and business training to ground-floor users and micro-enterprise users onto latch onto over many decades of growth,” he explained.
 
A bright future ahead

"The only thing that we have and you don’t is experience,” said Petria Smit, a lecturer at the Department. “Some of your talent far exceeds ours.” During the awards ceremony, she said it was a privilege to work with students of such impressive calibre.

The awards, which were hosted for the 32nd year, are a way for the Department, in collaboration with Corobrik, to reward the talent of students. Diedericks said his win was a great honour and worth the many hours he had sacrificed for this course. Having bagged his master’s, Diedericks’s future plans are to work for the City of Bloemfontein as an architect or on an urban level when an opportunity arises.


News Archive

Nuclear Medicine on the forefront of cancer research
2017-07-10

Description: Nuclear Medicine on the forefront of cancer research Tags: Nuclear Medicine, cancer research, Dr Je’nine Horn-Lodewyk’s, tumour detection method, cancer, Department of Nuclear Medicine 

Dr Je’nine Horn-Lodewyk’s tumour detection method
could be the cost-effective breakthrough needed to decrease
the mortality rate in breast cancer patients.
Photo: Anja Aucamp

The field of Nuclear Medicine in South Africa and the rest of the world are expanding rapidly due to the development of hybrid cameras and new radiopharmaceuticals. These developments have a huge impact on the diagnosis and therapy of cancer.

The most advanced of these cameras, Positron emission tomography combined with normal CTs (PETCT), are not yet widely available in South Africa due to the cost of the cameras and the radiopharmaceuticals. A more cost-effective alternative can be of great benefit. To achieve this, the focus should be on developing new radiopharmaceuticals that can be used with the current cost-effective gamma cameras, according to University of the Free State researcher, Dr Je’nine Horn-Lodewyk from the Department of Nuclear Medicine.

Fluorodeoxyglucose (18F-FDG), a radiolabelled glucose analogue, is currently the radiopharmaceutical most commonly used in PET/CT imaging for mainly oncology indications. Although it is considered the gold standard for imaging in several malignancies, it does have certain disadvantages. An 18F-FDG PET/CT diagnostic imaging study can cost between R25 000 and R35 000 for a single patient in the private sector. The 18F-FDG is also more radioactive, which requires much stricter handling and shielding to avoid high radiation dosages to staff and patients.

Successful research potential innovative solution
In the search for the ideal radiopharmaceutical for tumour detection, the South African National Nuclear Energy Corporation (Necsa) developed a local synthesis process for ethylenedicysteine-deoxyglucose (EC-DG). EC-DG is also a glucose analogue similar to FDG. They succeeded in labelling the compound with Technetium-99-metastable-pertechnetate (99mTcO4-), the most common nuclear medicine isotope used for approximately 95% of nuclear medicine procedures, creating 99mTc-EC-DG.

In partnership with Dr Horn-Lodewyk, this compound was successfully used in various animal models and clinical scenarios, resulting in approval by the Medicine Control Council to use it in a human study. Research is also planned in order to investigate diagnostic accuracy in other cancers like lymphoma.  The end result of this research can produce a radiopharmaceutical that is cost effective, does not require the use of costly specialised equipment, has no significant side-effects, no special patient preparation, renders late imaging possible, and has decreased radiation risks.

Dr Horn-Lodewyk is grateful for the support of her mentor, Prof Anton Otto, as well as Dr Gert Engelbrecht, Head of the Department of Nuclear Medicine, Prof Jan Rijn Zeevaart from North-West University’s Preclinical Drug Development Platform and Necsa, and Judith Wagener from Necsa. This innovative research would also not have been possible without the financial assistance of Dr Glen Taylor and Eleanor van der Westhuizen in the Directorate of Research Development.

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