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08 July 2019 | Story Xolisa Mnukwa | Photo Charl Devenish
Thought-Leader Series 2019
Executive Director: Centre for Politics and Research and political commentator, Prince Mashele, one of the key experts at the UFS Thought-Leader series, advises the youth in South Africa on acquiring multidisciplinary skills in order to survive in the future world of work.

The University of the Free State (UFS), in collaboration with Vrye Weekblad, presented the second consecutive Thought-Leader series on the Bloemfontein Campus on 4 July 2019, with topics focusing on economic growth and entrepreneurship for an emergent South African economy and environment. The series formed part of the literature festival of the Vrystaat Arts Festival, presented on the campus from 1 to 7 July 2019.

Rector and Vice-Chancellor of the UFS, Prof Francis Petersen, opened the discussions with the words, “We need to project ourselves as thought-leaders,” clarifying that the UFS itself is responsible for contributing to local and national public discourse by assembling industry experts to deliberate on imperative topics that affect students, the broader community, and the country in one way or another.  

Editor of the Vrye Weekblad, political analyst, and master of ceremonies for the morning, Dr Max du Preez, introduced the panellists for the first discussion, themed How can we fix the South African economy and create jobs.

According to Prof Philippe Burger, Vice-Dean (Strategic Projects): UFS Faculty of Economic and Management Sciences, South Africa has the highest level of economic inequality in the world. He further explained that the long-term solution to growing the country’s economy is to improve the quality of education, which will result in a higher growth rate for the country.

Chief Economist at Investec, Ms Annabel Bishop, went on to explain that, “South Africa has a worrying de-industrialisation trend, which contributes to the decreased opportunity for decent job creation, essentially contributing to our struggling economy.” This was echoed by Executive Director: Centre for Politics and Research and political commentator, Mr Prince Mashele, who spoke on employing the unemployed. He suggested that South Africa’s youth be trained and equipped with skills so that SA gravitate more towards producing an industrial class in order to build its economy.

Director and Chief Economist of the Efficient Group, Mr Dawie Roodt, concluded the first discussion by highlighting that South Africa needs a GDP growth rate of 2,5% to at least maintain the country’s current unemployment rate and prevent it from getting worse. 

The second panel discussed the establishment of a pro-youth entrepreneurship country, where the Head: Department of Business Management (UFS), Prof Brownhilder Neheh, spoke about bridging the intention-behaviour gap, and further exposing the youth to practical opportunities and teaching them the importance of group mentality as entrepreneurs. Chief Executive Officer: Harambee Youth Employment Accelerator, Ms Maryana Iskander, suggested that foreign direct investment can improve youth employment.

The final panellist to speak during the last half of the discussion, Senior Banker and Transactor: Acquisition and Leveraged Finance Division at Rand Merchant Bank – Corporate Investment Bank, Mr David Abbey, advised on tomorrow’s world of work by saying, “The focus of the workplace should always be on the people, and entrepreneurs should understand the importance of multidisciplinary skills, and emotional and social intelligence, as the future world of work requires a trusted society.”

 


UFS Thought-Leader Series
Programme: 

 

UFS Thought-Leader Series
Panel discussions:

 
 UFS Thought-Leader Series Programme  
 



News Archive

Nuclear Medicine on the forefront of cancer research
2017-07-10

Description: Nuclear Medicine on the forefront of cancer research Tags: Nuclear Medicine, cancer research, Dr Je’nine Horn-Lodewyk’s, tumour detection method, cancer, Department of Nuclear Medicine 

Dr Je’nine Horn-Lodewyk’s tumour detection method
could be the cost-effective breakthrough needed to decrease
the mortality rate in breast cancer patients.
Photo: Anja Aucamp

The field of Nuclear Medicine in South Africa and the rest of the world are expanding rapidly due to the development of hybrid cameras and new radiopharmaceuticals. These developments have a huge impact on the diagnosis and therapy of cancer.

The most advanced of these cameras, Positron emission tomography combined with normal CTs (PETCT), are not yet widely available in South Africa due to the cost of the cameras and the radiopharmaceuticals. A more cost-effective alternative can be of great benefit. To achieve this, the focus should be on developing new radiopharmaceuticals that can be used with the current cost-effective gamma cameras, according to University of the Free State researcher, Dr Je’nine Horn-Lodewyk from the Department of Nuclear Medicine.

Fluorodeoxyglucose (18F-FDG), a radiolabelled glucose analogue, is currently the radiopharmaceutical most commonly used in PET/CT imaging for mainly oncology indications. Although it is considered the gold standard for imaging in several malignancies, it does have certain disadvantages. An 18F-FDG PET/CT diagnostic imaging study can cost between R25 000 and R35 000 for a single patient in the private sector. The 18F-FDG is also more radioactive, which requires much stricter handling and shielding to avoid high radiation dosages to staff and patients.

Successful research potential innovative solution
In the search for the ideal radiopharmaceutical for tumour detection, the South African National Nuclear Energy Corporation (Necsa) developed a local synthesis process for ethylenedicysteine-deoxyglucose (EC-DG). EC-DG is also a glucose analogue similar to FDG. They succeeded in labelling the compound with Technetium-99-metastable-pertechnetate (99mTcO4-), the most common nuclear medicine isotope used for approximately 95% of nuclear medicine procedures, creating 99mTc-EC-DG.

In partnership with Dr Horn-Lodewyk, this compound was successfully used in various animal models and clinical scenarios, resulting in approval by the Medicine Control Council to use it in a human study. Research is also planned in order to investigate diagnostic accuracy in other cancers like lymphoma.  The end result of this research can produce a radiopharmaceutical that is cost effective, does not require the use of costly specialised equipment, has no significant side-effects, no special patient preparation, renders late imaging possible, and has decreased radiation risks.

Dr Horn-Lodewyk is grateful for the support of her mentor, Prof Anton Otto, as well as Dr Gert Engelbrecht, Head of the Department of Nuclear Medicine, Prof Jan Rijn Zeevaart from North-West University’s Preclinical Drug Development Platform and Necsa, and Judith Wagener from Necsa. This innovative research would also not have been possible without the financial assistance of Dr Glen Taylor and Eleanor van der Westhuizen in the Directorate of Research Development.

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