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02 July 2019 | Story Leonie Bolleurs
Edwin Skhosana
Edwin Skhosana is working hard to become a successful and competent actuary one day. With him is his lecturer, Dr Michael von Maltitz.

Edwin Skhosana, an Actuarial Sciences student, was described by his lecturer, Dr Michael von Maltitz of the Department of Mathematical Statistics and Actuarial Science, as ‘very quiet’ in his Causal Inference class. 

This may sound like a compliment, but it’s not.

For Dr Von Maltitz, being quiet is definitely not encouraged – not with the new teaching methods applied in class.

“See, my class is all about engagement – getting the students to watch videos on the topics, read about the methods in question, and then come to class to grill me about things they don’t understand. This change in teaching method is extremely disconcerting for many Mathematical students, who have up until now only been taught in the ‘memorise-regurgitate’ form they had ever since the start of high school,” he explains.

Future success


“My goal is to get the students to a level of understanding where they can sit down with me or with an expert in the field and have a conversation about the Mathematical Statistics topics that I teach. This is a very difficult task in such a technical module, and few students ever feel comfortable enough to engage with me actively in class in this way,” Dr Von Maltitz points out. 

Edwin is working hard towards applying the skills and knowledge he has obtained at university to become a successful and competent actuary one day. 

An important turning point was when it dawned on him how the things discussed in class could find an important practical application in so many fields.  

“This suddenly drove a spontaneous fascination in my mind that led me to engage with Dr Von Maltitz,” the previously quiet Edwin explains.

And everything changed.

Desperate to learn

Dr Von Maltitz explains: “Edwin came to my office to ask some questions. The incredible thing was that he sat down, and a conversation about the Mathematics, the foundations, and the methods just flowed between us. I have seldom had such an insightful chat about my module with a student. It was like a cascade of information just fell into place for Edwin.”

Although he sometimes still experiences his studies as challenging and grapples to adapt to the various styles of lecturing from different lecturers, Edwin now has hope for his class in Causal Inference. 

“I think Dr Von Maltitz’s way of presenting in class is excellent. It is, however, hard to grasp if you are still anchored in the old way of cramming, because he wants you to understand and be able to apply what he teaches,” says Edwin.

“It was just wonderfully refreshing to see someone so desperate to learn something (rather than just wanting to get a degree), and then actually managing to turn around a bad semester mark into such a river of understanding,” Dr Von Maltitz concludes.

Dr Michael von Maltitz
Dr Micheal von Maltitz

News Archive

Collaboration between UFS and Mayo Clinic to revolutionise cancer treatment
2014-06-27



Attending the lecture were, from the left: Dr Chantel Swart, Prof Lodewyk Kock, Prof Debabrata Mukhopadhyay, Prof James du Preez; back: Prof Pieter van Wyk.
Dr Swart, Profs Kock and Du Preez are from the Department of Microbial, Biochemical and Food Biotechnology. Prof Mukhopadhyay is from the Mayo Clinic (US) and Prof Van Wyk is from the Centre for Microscopy at the UFS.
Photo: Supplied
The UFS made a discovery that may have enormous implications for the treatment of diseases in humans.

Since the discovery, the UFS joined forces with the Mayo Clinic in Rochester, US, in the fight against cancer.

In this collective effort, UFS researchers would be able to assist the Mayo team to:
• see how treatment in cancer patients is progressing,
• target treatments more effectively,
• reduce dosages in order to make treatment gentler on the patient,
• track the effectiveness of the chemotherapy drugs used, and
• gain an accurate view of how the cancer is being eliminated.

Prof Lodewyk Kock, Outstanding Professor at the Department of Microbial, Biochemical and Food Biotechnology, and his team incidentally created a technique to use argon gas particles for the first time on biological material to slice open cells to look inside.

The team that supported Prof Kock includes Dr Chantel Swart, Khumisho Dithebe (PhD student), Prof Hendrik Swart (Department of Physics) and Prof Pieter van Wyk (Centre for Microscopy).

Prof Debabrata Mukhopadhyay from the Mayo Clinic in Rochester, US, got to hear about this breakthrough at the UFS and a collaboration between the two institutions was established.

During a visit to the Bloemfontein Campus, Prof Mukhopadhyay explained novel techniques that make use of gold nanoparticles. These particles attach to chemotherapeutic drugs to selectively target cancer cells – dramatically decreasing the side effects to normal human cells.

For these new drugs (coupled to gold nanoparticles) to be accepted into clinical practice, visual and chemical proof is needed, though. This is where the technique developed by the UFS will play a vital role.

With the technique to look inside cells, the composition, location and metabolism of these drugs can be determined. This will aid in a proof of concept for the application of the nano-drugs. Furthermore, it will enable approval for use of these drugs in clinical trials and eventually could revolutionise cancer treatment as a whole.

For video lectures on the technique used, as well as its findings, follow these links:

1. http://vimeo.com/63643628 (Comic version for school kids)

2. http://vimeo.com/61521401 (Detailed version for fellow scientists)

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