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22 July 2019 | Story Zama Feni | Photo Rene Jansen
UFS Mandela Day
Students from the UFS Faculty of Health Sciences cutting grass and planting trees at the Badernhorst Street entrance to the Bloemfontein Campus

On Nelson Mandela International Day, groups of staff from the University of the Free State (UFS) reached out to the needy, devoting a little of their time to make a difference in the community; this was in reaction to the national call to participate in charitable activities on the day.

This year is the tenth anniversary of Nelson Mandela International Day, when people are encouraged to spend at least 67 minutes of their time in commemoration of the birthday of the late struggle icon and former president of the Republic of South Africa, Nelson Mandela; however, the goodwill efforts of UFS staff went far beyond the required time.

Psychology Student Association encourages civic responsibility 

The Faculty of the Humanities celebrated Mandela Day with the Psychology Student Association (PSA) at the Rag Farm on the Bloemfontein Campus of the University of the Free State on 19 July 2019. The students were provided an opportunity to better themselves and to get information on opportunities awaiting them as Psychology graduates. Mabatho Ntsieng, Community Engagement Officer, encouraged students to continue to be of service to the community of Bloemfontein. “Community engagement is not just about improving your CV or bettering your chances to be accepted into the Psychology master’s programme,” she said.

Students were encouraged to regularly reflect on aspects that will enable personal growth and will help to understand the benefits of community engagement. The faculty prides itself in producing graduates who understand their civic responsibility. Empathy, knowledge, and involvement are the three values promoted in the PSA; these values assist in developing well-rounded individuals.

Dr Molelekoa Kometsi, Lecturer in the Department of Psychology, and Kaylene Pillay, a student in the master’s programme, were invited as guest speakers. The UFS Careers Office was invited to explain to students the changes that are already happening in the world of work, and how to upskill and reskill themselves in order to stay more relevant in the ever-changing world.

Blankets for hospital patients

Chants of joy reverberated through the passages of the Pelonomi Hospital yesterday as the Friends of Pelonomi team, led by the UFS Head of the School of Clinical Medicine, Prof Nathaniel Mofolo, handed over 41 blankets to the Pelonomi Hospital’s postnatal ward. 

Operational Manager for Maternity at the hospital, Tseleng Kodisang, was grateful to the university team for lending a helping hand to the hospital.

“We sometimes get women who need maternity assistance at our hospital, and they come with bare hands – I mean with literally nothing, so these blankets will help in such cases,” she said. 

Prof Mofolo thanked all those who made donations.

“This is the start, not the end,” he promised.

UFS students give pavement a facelift

A stretch of pavement of a little more than 100 metres in front of the UFS’ Gate 2 looks much better now after students from the university’s Faculty of Health Sciences gave it a bit of a face-lift in celebration of Nelson Mandela International Day.

The pavement in front of the Free State Provincial Archives is now neatly trimmed and boasts some succulents in brightly coloured tyres, surrounded by concrete stones.

Coordinator of this programme, Ms Ronelle Jansen, said: “We hope that all the efforts we have made here will help to change the look of this entrance.” 

Head of the Free State Provincial Archives, Tshitso Challa, and his team also assisted the university team with cutting grass and cleaning the pavement.

“We thank the university for initiating this. It is a reflection of partnership. We, as the staff, decided not to sit and watch, but to join and contribute as well,” he said.

Knitting to keep children warm

Eugene Seegers reports that staff members linked to the research division on the South Campus for Open Distance Learning, took to needles and wool for the Masikhule NGO's 67 Minutes for Mandela Day project, Cast on 4 Kids

They have been knitting many multi-coloured squares over the past year. These will be sewn into blankets to keep children, who attend the early childhood development centres (such as crèches) in impoverished communities, warm.

One of the members of the South Campus knitting group, Nelia Oosthuysen, said, “We hope to expand the project and involve more colleagues on campus in the coming year.” 

She added that some of the gentlemen on the South Campus are already part of the knitting crew, while others have intrepidly ventured into uncharted waters and learnt basic knitting techniques. 
“This is not only a community-service project, but also a very effective destressing method,” said Oosthuysen.

Encouraging a culture of learning

Eloise Calitz reports that fourteen UFS Library staff members spent their 67 minutes at the local Botlehadi Primary School, where they cleaned the library space, classified books, and trained two teachers and 18 learners in library administration. The purpose was to encourage the 400 learners at the school to develop a culture of reading.

During the handover, Library Director Betsy Eister, said, “Teachers should lead by example by also reading and using the library. By doing that, the learners will follow, and we will indeed achieve the dream of a reading nation.”

FARMOVS reaches out to animal shelter 

Staff members from the FARMOVS Clinical Research Facility spent the morning of Mandela Day at the New Beginnings Animal Rescue Centre, where they dropped off donations and helped to exercise and groom destitute animals.

“It was a great experience for all of us,” says Lee-Anne Reineke of the FARMOVS Social Committee. “Our staff really opened their hearts for this wonderful organisation that does such valuable work, not only in aid of animal welfare, but also reaching out to needy people in the vicinity. We managed to donate a large amount of money as well as a lot of food, blankets, toys, collars, and gift packs for the children.”


News Archive

UFS study on cell development in top international science journal
2008-09-16

A study from the University of the Free State (UFS) on how the change in the packaging of DNA with cell development influenced the expression of genes, will be published in this week’s early edition of the prestigious international, peer-reviewed science journal, the Proceeding of the National Academy of Sciences of the USA (PNAS).

The PNAS journal has an impact factor of 10, which means that studies published in the journal are, on average, referred to by ten other scientific studies in a two year period. The South African Journal of Science, by comparison, has an impact factor of 0.7.

The UFS study, funded by the Wellcome Trust and the National Research Foundation (NRF), looked at how the change in the packaging of DNA with cell development influenced the expression of genes. It is very relevant to research on stem cells, an area of medicine that studies the possible use of undifferentiated cells to replace damaged tissue.

Prof. Hugh Patterton, of the Department of Microbial, Biochemical and Food Biotechnology at the UFS, who led the study, said: "We are extremely proud of this study. It was conceived in South Africa, it was performed in South Africa, the data were analysed in South Africa, and it was published from South Africa."

When a gene is expressed, the information encoded in the gene is used to manufacture a specific protein. In eukaryotes, which include humans, there is approximately 1m of DNA, containing the genes, in every cell. This length of DNA has to fit into a cell nucleus with a diameter of only about 10 micrometer. In order to fit the DNA into such a small volume, eukaryotic cells wrap their DNA onto successive protein balls, termed nucleosomes. Strings of nucleosomes, resembling a bead of pearls, is folded into a helix to form a chromatin fiber. The study from the UFS investigated how the binding of a specific protein, termed a linker histone, that binds to the length of DNA between nucleosomes, influenced the formation of the chromatin fiber and also the activity of genes.

"We found that the linker histone bound to chromatin in yeast, which we use as a model eukaryote, under conditions where virtually all the genes in the organism were inactive. It was widely believed that the binding of the linker histone caused the inactivation of genes. We studied the relationship between the amount of linker histone bound in the vicinity of each gene and the expression of that gene for all the genes in yeast, using genomic techniques. We made the surprising discovery that even through the linker histone preferentially bound to genes under conditions where the genes were shut off, this inactivation of genes was not caused by the binding of the linker histone and folding of the chromatin,” said Prof. Patterton.

He said: “Instead our data strongly suggested that the observed anti-correlation was due to the movement of enzymes along the DNA molecule, involved in processing the information in genes for the eventual manufacture of proteins. This movement of enzymes displaced the linker histones from the DNA. This finding now requires a rethink on aspects of how packaging of DNA influences gene activity."

Prof. Patterton said that his research group, using the Facility for Genomics and Proteomics as well as the Bioinformatics Node at the UFS, was currently busy with follow-up studies to understand how other proteins in nucleosomes affected the activities of genes, as well as with projects to understand how chemicals found in red wine and in green tea extended lifespan. "We are certainly having a marvelous time trying to understand the fundamental mechanisms of life, and the UFS is an exciting place to be if one was interested in studying life at the level of molecules," he said.


Media Release
Issued by: Lacea Loader
Assistant Director: Media Liaison
Tel: 051 401 2584
Cell: 083 645 2454
E-mail: loaderl.stg@ufs.ac.za  
18 September 2008
 

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