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10 June 2019 | Story Zama Feni | Photo Zama Feni
CrazySocksForDocs
UFS medical students displaying multi-coloured mismatched socks as they heeded the call of the #CrazySocks4Doc campaign to raise awareness about mental health in the medical profession.

Hundreds of pairs of socks were dished out to medical students last week during the campus launch of the #CrazySocks4Docs (#CS4D) awareness campaign that seeks to help break the silence around mental-health illness in the medical profession.
 
More than 600 medical students from the University of the Free State (UFS) School of Internal Medicine heeded the call by the non-governmental organisation, Ithemba Foundation, whose mission is to educate the public around mental health – specifically depression and related diseases such as anxiety disorders – and to support research.

On Monday, 3 June 2019, the Ithemba Foundation launched the CS4D campaign countrywide at all tertiary institutions with medical schools to help break the silence around mental health in the medical profession. 

“We have ensured a sponsorship of 10 000 pairs of mismatched socks for medical students, to be distributed according to student numbers at each medical campus,” Ithemba Foundation said in a statement.

Students waking up to the call

A large number of UFS medical students gladly embraced the call and helped themselves to pairs of multi-coloured socks at the James Moroka Building foyer on the Bloemfontein Campus.

Judy Modise, a second-year medical student, said she was impressed with the initiative.
“I think this is a very interesting campaign, as we all know the devastating effects of mental health in society, and more specifically on doctors,” she said.

UFS has risen to the challenge

In a widely published opinion piece on mental health in October last year, UFS Rector and Vice-Chancellor Prof Francis Petersen, stated that one in every three South Africans suffers from some form of mental disorder.

He mentioned that, “The university has just released a first draft of its first-ever Student Mental Health Policy.”

“This policy seeks to redress the inequalities and disadvantages created by prejudice and discrimination against persons with mental-health disabilities and difficulties,” said Prof Petersen.
 
Destigmatising mental health is key

The Ithemba Foundation further stated that, “It is critical that we start the conversation around mental health in the health profession – especially among the next generation of medical professionals, as the stigma surrounding the illness in doctors persists. Wearing mismatched, brightly-coloured socks may seem like a weird place to begin, but to care for others, we also have to care for ourselves and each other.”

The purpose of the campaign is to create awareness about the highly stressful nature of the medical profession; the need for doctors to seek help when needed, both mental and physical; the need for those in the health profession to help one another and the need to reshape the culture of the health care industry and to ensure that you will have a new mindset concerning your own mental health. 


News Archive

UFS study on cell development in top international science journal
2008-09-16

A study from the University of the Free State (UFS) on how the change in the packaging of DNA with cell development influenced the expression of genes, will be published in this week’s early edition of the prestigious international, peer-reviewed science journal, the Proceeding of the National Academy of Sciences of the USA (PNAS).

The PNAS journal has an impact factor of 10, which means that studies published in the journal are, on average, referred to by ten other scientific studies in a two year period. The South African Journal of Science, by comparison, has an impact factor of 0.7.

The UFS study, funded by the Wellcome Trust and the National Research Foundation (NRF), looked at how the change in the packaging of DNA with cell development influenced the expression of genes. It is very relevant to research on stem cells, an area of medicine that studies the possible use of undifferentiated cells to replace damaged tissue.

Prof. Hugh Patterton, of the Department of Microbial, Biochemical and Food Biotechnology at the UFS, who led the study, said: "We are extremely proud of this study. It was conceived in South Africa, it was performed in South Africa, the data were analysed in South Africa, and it was published from South Africa."

When a gene is expressed, the information encoded in the gene is used to manufacture a specific protein. In eukaryotes, which include humans, there is approximately 1m of DNA, containing the genes, in every cell. This length of DNA has to fit into a cell nucleus with a diameter of only about 10 micrometer. In order to fit the DNA into such a small volume, eukaryotic cells wrap their DNA onto successive protein balls, termed nucleosomes. Strings of nucleosomes, resembling a bead of pearls, is folded into a helix to form a chromatin fiber. The study from the UFS investigated how the binding of a specific protein, termed a linker histone, that binds to the length of DNA between nucleosomes, influenced the formation of the chromatin fiber and also the activity of genes.

"We found that the linker histone bound to chromatin in yeast, which we use as a model eukaryote, under conditions where virtually all the genes in the organism were inactive. It was widely believed that the binding of the linker histone caused the inactivation of genes. We studied the relationship between the amount of linker histone bound in the vicinity of each gene and the expression of that gene for all the genes in yeast, using genomic techniques. We made the surprising discovery that even through the linker histone preferentially bound to genes under conditions where the genes were shut off, this inactivation of genes was not caused by the binding of the linker histone and folding of the chromatin,” said Prof. Patterton.

He said: “Instead our data strongly suggested that the observed anti-correlation was due to the movement of enzymes along the DNA molecule, involved in processing the information in genes for the eventual manufacture of proteins. This movement of enzymes displaced the linker histones from the DNA. This finding now requires a rethink on aspects of how packaging of DNA influences gene activity."

Prof. Patterton said that his research group, using the Facility for Genomics and Proteomics as well as the Bioinformatics Node at the UFS, was currently busy with follow-up studies to understand how other proteins in nucleosomes affected the activities of genes, as well as with projects to understand how chemicals found in red wine and in green tea extended lifespan. "We are certainly having a marvelous time trying to understand the fundamental mechanisms of life, and the UFS is an exciting place to be if one was interested in studying life at the level of molecules," he said.


Media Release
Issued by: Lacea Loader
Assistant Director: Media Liaison
Tel: 051 401 2584
Cell: 083 645 2454
E-mail: loaderl.stg@ufs.ac.za  
18 September 2008
 

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