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Fulbright scholar wants to improve lives of HIV/Aids patients

25 June 2019 | Story Leonie Bolleurs | Photo Barend Nagel

Marnus du Plooy will receive his master’s degree at the University of the Free State’s Winter Graduation Ceremony.

After completing his BSc degree in Microbiology, he discovered a passion for this field of research and enrolled for postgraduate studies in the Department of Microbial, Biochemical and Food Biotechnology at the UFS.

During his master’s, Du Plooy focused on the pathogenic yeasts, Cryptococcus neoformans and a related species, C. deneoformans.

Passion for science instilled at a young age

His passion for this field comes from a young age. “Both my parents were Science teachers and they instilled a love for Science in me. At school, I enjoyed the Science subjects the most and usually obtained my highest marks in these,” Du Plooy said.

The pathogenic yeasts studied by Du Plooy, Cryptococcus neoformans and the sister species, C. deneoformans, often cause meningitis in immunocompromised individuals, such as in people living with HIV/Aids.

He pointed out: “Infection caused by these yeasts is right on the heels of TB as the second largest killer of HIV-positive patients in sub-Saharan Africa. The focus of my master’s project was to investigate new ways in which genes can be ‘switched off’ in these yeasts in order to study the role of the genes in virulence. Doing so could help to identify new drug targets for the treatment of this form of meningitis in subsequent studies.”

Expanding his international footprint

Although Du Plooy received his master’s degree from the UFS, he grabbed the opportunity to study abroad with both hands. He applied for and received a Fulbright scholarship from the Fulbright Foreign Student Programme, giving him the opportunity to study in the US.

“I did not expect to get very far with the application, as very few candidates are selected each year. I was very lucky to receive a Fulbright scholarship and an admission offer from Duke University for PhD studies in Microbiology,” said Du Plooy.

He hopes to continue with research on Cryptococcus and to contribute to improving the lives of HIV/Aids patients. “I have always been interested in pharmaceutical and medical research and noticed a need for better cryptococcal treatments, especially in sub-Saharan Africa. Cryptococcal meningitis is a neglected disease which claims more than 600 000 lives worldwide every year. The current treatment options are several decades old, with some only available in well-resourced areas.”

Du Plooy will depart for the US in August. “The duration of the degree is four to five years, where-after I will return to South Africa to apply what I have learned at home.”

News Archive

Official opening of Faculty of Health Sciences Rural Community Initiative

2017-01-01

Description: Karla Mostert Tags: Mail & Guardian, 200 Young South Africans, Candice Thikeson, Karla Mostert, Lerato Machetela, Mandela Rhodes Scholar, Thapelo Mokoatsi

Ribbon cutting, Prof van Zyl and Ms du Plessis
Venter (community member)

The Faculty of Health Sciences of the University of the Free State (UFS) has, as part of its commitment to student and community development, established a student residence in the town of Trompsburg in the Kopanong Local municipality, Xhariep District municipality in the Southern Free State. The Faculty officially opened the Faculty of Health Sciences Rural Community Initiative on 14 and 15 June 2017. The memorial plaque was unveiled by Prof Gert van Zyl (Dean of the Faculty of Health Sciences) and Prof Francis Petersen (Rector and Vice-Chancellor of the University of the Free State)

The importance of the residence

The goal of the ‘Kopanang le fodise – Unite to heal’ programme is to develop a community-centered collaborative framework for sustainable, holistic healthcare and social development incorporated in the curricula of the Faculty.

Background of the project

During 2016 a total of 324 fourth-year students of the Faculty have each spend at least a week in interprofessional groups in primary healthcare facilities in the Kopanong municipality on a Community Based Education, Interprofessional Education (CBE-IPE) platform in Trompsburg and Springfontein.

To facilitate student rural placement the former Midway guesthouse currently includes seven (7) facilitator units with on suite bathrooms, two (2) fully equipped lecture facilities, a recreation room and a library with computers and internet access. The newly developed student residence has 10 apartments that can each accommodate six (6) individuals. A housemaster resides on the premises and acts as manager of the facility. All areas of the residence are Wifi covered and 24h security service is in place.

The ceremony was attend by the following partners

University of the Free State (UFS)

Rector and Vice Chancellor of the University of the Free State, Prof Francis Petersen.
Members of the UFS council, Dr Vinger and Dr Swart
Dean of the Faculty of Health Sciences, Prof van Zyl.
The Head of the School of Allied Health Professions, Dr van Vuuren.
The Head of the School of Medicine, Prof Kruger.
Faculty from the Faculty of Health Sciences.
Members from UFS institutional support department: ICT, Finance, Facilities management

Kopanong local municipality

Councilor Basholo, representing the Kopanong local municipality.
Kopanong local community members
Free State Department of Education (DoE)
Free State Department of Health (DoH)

Private sector partners

Mr Burgess, CEO of MDG Heath Solutions
The Mother And Child Academic Hospital (MACAH) represented by Prof Venter, head of department of Paediatrics, donated two (2) state of the art baby scales to the rural health programme.

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