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25 June 2019 | Story Leonie Bolleurs | Photo Barend Nagel
Marnus du Plooy
Marnus du Plooy, recipient of a Fulbright Scholarship, will depart for the Duke University in Durham, North Carolina, in August to complete a doctoral degree.

Marnus du Plooy will receive his master’s degree at the University of the Free State’s Winter Graduation Ceremony.

After completing his BSc degree in Microbiology, he discovered a passion for this field of research and enrolled for postgraduate studies in the Department of Microbial, Biochemical and Food Biotechnology at the UFS.

During his master’s, Du Plooy focused on the pathogenic yeasts, Cryptococcus neoformans and a related species, C. deneoformans.

Passion for science instilled at a young age

His passion for this field comes from a young age. “Both my parents were Science teachers and they instilled a love for Science in me. At school, I enjoyed the Science subjects the most and usually obtained my highest marks in these,” Du Plooy said. 

The pathogenic yeasts studied by Du Plooy, Cryptococcus neoformans and the sister species, C. deneoformans, often cause meningitis in immunocompromised individuals, such as in people living with HIV/Aids.

He pointed out: “Infection caused by these yeasts is right on the heels of TB as the second largest killer of HIV-positive patients in sub-Saharan Africa. The focus of my master’s project was to investigate new ways in which genes can be ‘switched off’ in these yeasts in order to study the role of the genes in virulence. Doing so could help to identify new drug targets for the treatment of this form of meningitis in subsequent studies.”

Expanding his international footprint

Although Du Plooy received his master’s degree from the UFS, he grabbed the opportunity to study abroad with both hands. He applied for and received a Fulbright scholarship from the Fulbright Foreign Student Programme, giving him the opportunity to study in the US.

“I did not expect to get very far with the application, as very few candidates are selected each year. I was very lucky to receive a Fulbright scholarship and an admission offer from Duke University for PhD studies in Microbiology,” said Du Plooy.

He hopes to continue with research on Cryptococcus and to contribute to improving the lives of HIV/Aids patients. “I have always been interested in pharmaceutical and medical research and noticed a need for better cryptococcal treatments, especially in sub-Saharan Africa. Cryptococcal meningitis is a neglected disease which claims more than 600 000 lives worldwide every year. The current treatment options are several decades old, with some only available in well-resourced areas.”

Du Plooy will depart for the US in August. “The duration of the degree is four to five years, where-after I will return to South Africa to apply what I have learned at home.”

News Archive

Mineral named after UFS professor
2017-09-29

Description: Mineral tredoux Tags: International Mineralogical Association, tredouxite, Prof Marian Tredoux, Department of Geology, Barberton 

Tredouxite (white) intergrown with bottinoite (light grey),
a complex hydrous alteration product. The large host
minerals are nickel-rich silicate (grey), maybe willemseite,
and the spinel trevorite (dark grey).


More than five thousand minerals have been certified by the International Mineralogical Association (IMA). One of these minerals, tredouxite, was recently named after an academic at the University of the Free State (UFS). 

Tredouxite was named after Prof Marian Tredoux, an associate professor in the Department of Geology, to acknowledge her close to 30 years’ commitment to figuring out the geological history of the rock in which this mineral occurs. The name was chosen by the team which identified the new mineral, consisting of Dr Federica Zaccarini and Prof. Giorgio Garuti from the University of Leoben, Austria, Prof. Luca Bindi from the University of Florence, Italy, and Prof. Duncan Miller from the UFS. 

They found the mineral in the abovementioned rock from the Barberton region in Mpumalanga, in May 2017.

In the past, a mineral was also named after Marie Curie
With the exception of a few historical (pre-1800) names, a mineral is typically named either after the area where it was first found, or after its chemical composition or physical properties, or after a person. If named after a person, it has to be someone who had nothing to do with finding the mineral.

Prof Tredoux said: “As of 19 September 2017, 5292 minerals had been certified by IMA. Of these, 81 were named after women, either singly or with a near relation. Marie Curie is named twice: sklodowskite (herself) and curite (plus husband). Most of the named women are Russian geoscientists.”

Another way to assess the rarity of such a naming is to consider that fewer than 700 minerals have been named after people. Given that there are by now seven billion people on the planet, it means that a person who is granted a mineral name becomes one in 10 million of the people alive today to be honoured in such a way. To date, over a dozen minerals had been named after South Africans, three of them after women (including tredouxite).

It contains nickel, antimony and oxygen
The chemical composition of tredouxite is NiSb2O6 (nickel antimony oxide). This makes it the nickel equivalent of the magnesium mineral bystromite (MgSb2O6), described in the 1950s from the La Fortuna antimony mine in Mexico.  

“This announcement is of great academic importance: the discovery by the Italian team of a phase with that specific chemical composition will undoubtedly help me and my co-workers to better understand the origin of the rock itself,” she said. She also expressed the hope that it may raise interest in the Department of Geology and the UFS as a whole, by highlighting that world-class research is being done at the department. 

The announcement of this new mineral was published on the International Mineralogical Association Commission on New Minerals, Nomenclature and Classification website, the Mineralogical Magazine and the European Journal of Mineralogy.

 

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