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25 June 2019 | Story Leonie Bolleurs | Photo Barend Nagel
Marnus du Plooy
Marnus du Plooy, recipient of a Fulbright Scholarship, will depart for the Duke University in Durham, North Carolina, in August to complete a doctoral degree.

Marnus du Plooy will receive his master’s degree at the University of the Free State’s Winter Graduation Ceremony.

After completing his BSc degree in Microbiology, he discovered a passion for this field of research and enrolled for postgraduate studies in the Department of Microbial, Biochemical and Food Biotechnology at the UFS.

During his master’s, Du Plooy focused on the pathogenic yeasts, Cryptococcus neoformans and a related species, C. deneoformans.

Passion for science instilled at a young age

His passion for this field comes from a young age. “Both my parents were Science teachers and they instilled a love for Science in me. At school, I enjoyed the Science subjects the most and usually obtained my highest marks in these,” Du Plooy said. 

The pathogenic yeasts studied by Du Plooy, Cryptococcus neoformans and the sister species, C. deneoformans, often cause meningitis in immunocompromised individuals, such as in people living with HIV/Aids.

He pointed out: “Infection caused by these yeasts is right on the heels of TB as the second largest killer of HIV-positive patients in sub-Saharan Africa. The focus of my master’s project was to investigate new ways in which genes can be ‘switched off’ in these yeasts in order to study the role of the genes in virulence. Doing so could help to identify new drug targets for the treatment of this form of meningitis in subsequent studies.”

Expanding his international footprint

Although Du Plooy received his master’s degree from the UFS, he grabbed the opportunity to study abroad with both hands. He applied for and received a Fulbright scholarship from the Fulbright Foreign Student Programme, giving him the opportunity to study in the US.

“I did not expect to get very far with the application, as very few candidates are selected each year. I was very lucky to receive a Fulbright scholarship and an admission offer from Duke University for PhD studies in Microbiology,” said Du Plooy.

He hopes to continue with research on Cryptococcus and to contribute to improving the lives of HIV/Aids patients. “I have always been interested in pharmaceutical and medical research and noticed a need for better cryptococcal treatments, especially in sub-Saharan Africa. Cryptococcal meningitis is a neglected disease which claims more than 600 000 lives worldwide every year. The current treatment options are several decades old, with some only available in well-resourced areas.”

Du Plooy will depart for the US in August. “The duration of the degree is four to five years, where-after I will return to South Africa to apply what I have learned at home.”

News Archive

UFS medical students reach out to the community
2011-04-16

 

The smiles on the children at Beyang Bana Pele Creche in Mangaung were blindingly bright, after their new classrooms and playground were unveiled on Friday 15 April. The creche was renovated by a group of third-year medical students from the UFS.
Photo: Earl Coetzee

A group of third-year medical students from the University of the Free State was responsible for many smiling little faces when they unveiled a entirely renovated crèche to its little students on Friday, 15 April.

Reinhardt Erasmus, Fathima Vawda, Veneshree Govender, Antoi Roets, Riaan Calitz, Motlalepula Mabizela, Tertius Potgieter and Chanel van der Westhuizen were the students responsible for the massive renovation work that went into the Beyang Bana Pele Creché in Mangaung.

The students tackled the project as part of a community service project and ensured that the 30 children who attend the crèche can look forward to coming to a safe healthy environment every day.

According to Riaan Calitz, they started the project at the beginning of the year by doing a needs analysis and talking to the children’s parents and teachers. They also involved the aid of an architect and quantity surveyor to calculate the needs of the crèche.

Next, they had to search for sponsors for their work, and struck it lucky when the Windmill Casino agreed to donate R100 000 to their project. They also managed to raise a further R5 000 as well as approximately R50 000 in goods and services donated by various other companies.

This money was enough to improve the safety at the crèche, install safe gas equipment in the kitchen, improve the insulation to ensure a warm winter, install new playground equipment and host several health and safety workshops.

“It took a lot of late nights and early mornings,” Calitz said. “Some of us also had to return from our holiday early, but it was worth it.”

He says the gratitude from the school’s children and teachers, as well as community members, who would stop and thank them for their help while they were busy working, makes it all worthwhile.

The students plan to stay involved with the crèche and say the renovation plan was drafted in such a way that when they move along, another group can simply pick up from their work with ease.

Mrs Sarah Mothoana, the crèche matron, thanked the students as well as everyone who assisted them in “creating a wonderful, safe and healthy environment for the children.”
 

 

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