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25 June 2019 | Story Leonie Bolleurs | Photo Barend Nagel
Marnus du Plooy
Marnus du Plooy, recipient of a Fulbright Scholarship, will depart for the Duke University in Durham, North Carolina, in August to complete a doctoral degree.

Marnus du Plooy will receive his master’s degree at the University of the Free State’s Winter Graduation Ceremony.

After completing his BSc degree in Microbiology, he discovered a passion for this field of research and enrolled for postgraduate studies in the Department of Microbial, Biochemical and Food Biotechnology at the UFS.

During his master’s, Du Plooy focused on the pathogenic yeasts, Cryptococcus neoformans and a related species, C. deneoformans.

Passion for science instilled at a young age

His passion for this field comes from a young age. “Both my parents were Science teachers and they instilled a love for Science in me. At school, I enjoyed the Science subjects the most and usually obtained my highest marks in these,” Du Plooy said. 

The pathogenic yeasts studied by Du Plooy, Cryptococcus neoformans and the sister species, C. deneoformans, often cause meningitis in immunocompromised individuals, such as in people living with HIV/Aids.

He pointed out: “Infection caused by these yeasts is right on the heels of TB as the second largest killer of HIV-positive patients in sub-Saharan Africa. The focus of my master’s project was to investigate new ways in which genes can be ‘switched off’ in these yeasts in order to study the role of the genes in virulence. Doing so could help to identify new drug targets for the treatment of this form of meningitis in subsequent studies.”

Expanding his international footprint

Although Du Plooy received his master’s degree from the UFS, he grabbed the opportunity to study abroad with both hands. He applied for and received a Fulbright scholarship from the Fulbright Foreign Student Programme, giving him the opportunity to study in the US.

“I did not expect to get very far with the application, as very few candidates are selected each year. I was very lucky to receive a Fulbright scholarship and an admission offer from Duke University for PhD studies in Microbiology,” said Du Plooy.

He hopes to continue with research on Cryptococcus and to contribute to improving the lives of HIV/Aids patients. “I have always been interested in pharmaceutical and medical research and noticed a need for better cryptococcal treatments, especially in sub-Saharan Africa. Cryptococcal meningitis is a neglected disease which claims more than 600 000 lives worldwide every year. The current treatment options are several decades old, with some only available in well-resourced areas.”

Du Plooy will depart for the US in August. “The duration of the degree is four to five years, where-after I will return to South Africa to apply what I have learned at home.”

News Archive

UFS academic appointed as team doctor for SA Olympic Team
2012-03-22

 

Dr Holtzhausen’s appointment reflects well on the quality of exercise and sports medicine presented at the university.
20 March 2012

Dr Louis Holtzhausen, Head of the university’s Department of Sports and Exercise Medicine, has been selected by the South African Sports Confederation and Olympic Committee (Sascoc) as team doctor for the more than 300 athletes that will represent South Africa at this year’s Olympic Games in London.

“This is definitely one of the most important highlights of my career, in which I’ve worked with professional athletes and top sporting people,” says Dr Holtzhausen, a recognised South African academic in Sports Medicine.

“It is not only an honour to be appointed as team doctor for the South African Olympic Team. It is also a privilege to represent the UFS. The fact that Sascoc approached me reflects well on the quality of exercise and sports medicine that we present here at the university,” says Dr Holtzhausen.

Dr Holtzhausen says he has already worked with some of the athletes in the Olympic Team. These include members of the South African boxing team, the hockey team, as well as track and field athletes that have been preparing for the Olympic Games at the university’s High Performance Unit.

There is, however, hard work ahead for Dr Holtzhausen. His work will start before the team leaves for London in July. “I have to ensure that all the athletes are healthy and that everyone’s immunisation programmes are up to date. We also have to ensure that no athlete takes banned substances,” he says.

During the Games, Dr Holtzhausen will keep an eye on the optimal functioning of every athlete. “Anything that could hamper them medically will be sorted – whether it’s a broken ankle or a cold,” he says.

He will also see to it that medical services are available during the competition. Immediate medical assistance will be available, especially at high contact sports like boxing.

Dr Holtzhausen has also been team doctor for Team South Africa at the All Africa Games, the biggest sporting event in Africa. He was recently appointed as a member of the International Committee and Coordinator for Africa of the worldwide Exercise is Medicine project. This project proposes that exercise be used in the prevention of chronic disease in the general population, as well as in the treatment of people with existing chronic diseases. Dr Holtzhausen is also an honorary member of the South African Sports Medicine Association (SASMA). This membership is awarded to members of the medical and scientific community who make significant contributions to the advancement of sports medicine.

Dr Holtzhausen is a member of the Vice-Chancellor’s Prestige Scholars Programme.
The goal with the Prestige Scholars Programme is to select no more than 100 of the most promising young scholars (typically holding lecturer status) and to make substantial investments in their development towards the professoriate. A tailored, intensive programme of support has been designed which combines international placement working alongside leading scholars in the discipline of the prestige scholar, with intensive mentorship and support from within the university.

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