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25 June 2019 | Story Leonie Bolleurs | Photo Barend Nagel
Marnus du Plooy
Marnus du Plooy, recipient of a Fulbright Scholarship, will depart for the Duke University in Durham, North Carolina, in August to complete a doctoral degree.
Marnus du Plooy will receive his master’s degree at the University of the Free State’s Winter Graduation Ceremony.

After completing his BSc degree in Microbiology, he discovered a passion for this field of research and enrolled for postgraduate studies in the Department of Microbial, Biochemical and Food Biotechnology at the UFS.

During his master’s, Du Plooy focused on the pathogenic yeasts, Cryptococcus neoformans and a related species, C. deneoformans.

Passion for science instilled at a young age

His passion for this field comes from a young age. “Both my parents were Science teachers and they instilled a love for Science in me. At school, I enjoyed the Science subjects the most and usually obtained my highest marks in these,” Du Plooy said. 

The pathogenic yeasts studied by Du Plooy, Cryptococcus neoformans and the sister species, C. deneoformans, often cause meningitis in immunocompromised individuals, such as in people living with HIV/Aids.

He pointed out: “Infection caused by these yeasts is right on the heels of TB as the second largest killer of HIV-positive patients in sub-Saharan Africa. The focus of my master’s project was to investigate new ways in which genes can be ‘switched off’ in these yeasts in order to study the role of the genes in virulence. Doing so could help to identify new drug targets for the treatment of this form of meningitis in subsequent studies.”

Expanding his international footprint

Although Du Plooy received his master’s degree from the UFS, he grabbed the opportunity to study abroad with both hands. He applied for and received a Fulbright scholarship from the Fulbright Foreign Student Programme, giving him the opportunity to study in the US.

“I did not expect to get very far with the application, as very few candidates are selected each year. I was very lucky to receive a Fulbright scholarship and an admission offer from Duke University for PhD studies in Microbiology,” said Du Plooy.

He hopes to continue with research on Cryptococcus and to contribute to improving the lives of HIV/Aids patients. “I have always been interested in pharmaceutical and medical research and noticed a need for better cryptococcal treatments, especially in sub-Saharan Africa. Cryptococcal meningitis is a neglected disease which claims more than 600 000 lives worldwide every year. The current treatment options are several decades old, with some only available in well-resourced areas.”

Du Plooy will depart for the US in August. “The duration of the degree is four to five years, where-after I will return to South Africa to apply what I have learned at home.”

News Archive

‘Leadership is formed through ethical behaviour’
2012-08-20

Mr Edward Kieswetter
20 August 2012

“Being ethical is not about what we can do, it is about what we ought to do.” This is according to Mr Edward Kieswetter, Group Executive of Alexander Forbes Limited. During his lecture to MBA students in the Business School, Mr Kieswetter allowed the audience to engage in a discussion about ethics and leadership in the business world. Mr Kieswetter is also Vice-Chairperson of the UFS Council.

Part of the lecture was discussing South Africa as a country that was not born in ethics. Mr Kieswetter commented that although context was is very important in making decisions, South African people tended to, for example, and “feed on corruption, instead of acting actively against it”. Questions about South Africa’s ethical foundation were raised. Mr Kieswetter explained that one of the greatest challenges with the South Africans was to help them understand that a person always had a choice. “If you have to compromise on your own values, you are not doing anybody justice.”

Ethics can promote common and social goals if they are not determined by what people feel and strive to reach beyond the barriers that religious beliefs put up. He shared of his life’s most valuable lessons learned about people in leadership positions. “A great leader has incredible self-awareness and displays a huge amount of humility.” He said that in life it was not about being perfect; it was rather about being authentic, even in challenging times where the outcome might affect the current situation negatively. “My greatest successes came from lessons I learned in making mistakes and growing from them.

“If you have nothing to die for, then what is there to live for?” Mr Kieswetter said when asked whether he would compromise his financial position if he did not agree with the ethics of the company he worked for. “By constantly complaining instead of progressing, we are giving up our power to change, and that is a scary thing for South Africa as a developing country.” 
 

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