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Fulbright scholar wants to improve lives of HIV/Aids patients

25 June 2019 | Story Leonie Bolleurs | Photo Barend Nagel

Marnus du Plooy will receive his master’s degree at the University of the Free State’s Winter Graduation Ceremony.

After completing his BSc degree in Microbiology, he discovered a passion for this field of research and enrolled for postgraduate studies in the Department of Microbial, Biochemical and Food Biotechnology at the UFS.

During his master’s, Du Plooy focused on the pathogenic yeasts, Cryptococcus neoformans and a related species, C. deneoformans.

Passion for science instilled at a young age

His passion for this field comes from a young age. “Both my parents were Science teachers and they instilled a love for Science in me. At school, I enjoyed the Science subjects the most and usually obtained my highest marks in these,” Du Plooy said.

The pathogenic yeasts studied by Du Plooy, Cryptococcus neoformans and the sister species, C. deneoformans, often cause meningitis in immunocompromised individuals, such as in people living with HIV/Aids.

He pointed out: “Infection caused by these yeasts is right on the heels of TB as the second largest killer of HIV-positive patients in sub-Saharan Africa. The focus of my master’s project was to investigate new ways in which genes can be ‘switched off’ in these yeasts in order to study the role of the genes in virulence. Doing so could help to identify new drug targets for the treatment of this form of meningitis in subsequent studies.”

Expanding his international footprint

Although Du Plooy received his master’s degree from the UFS, he grabbed the opportunity to study abroad with both hands. He applied for and received a Fulbright scholarship from the Fulbright Foreign Student Programme, giving him the opportunity to study in the US.

“I did not expect to get very far with the application, as very few candidates are selected each year. I was very lucky to receive a Fulbright scholarship and an admission offer from Duke University for PhD studies in Microbiology,” said Du Plooy.

He hopes to continue with research on Cryptococcus and to contribute to improving the lives of HIV/Aids patients. “I have always been interested in pharmaceutical and medical research and noticed a need for better cryptococcal treatments, especially in sub-Saharan Africa. Cryptococcal meningitis is a neglected disease which claims more than 600 000 lives worldwide every year. The current treatment options are several decades old, with some only available in well-resourced areas.”

Du Plooy will depart for the US in August. “The duration of the degree is four to five years, where-after I will return to South Africa to apply what I have learned at home.”

News Archive

UFS Rose Ball promises to be an unforgettable experience

2005-09-08

On Saturday 15 of October 2005, the Department of Paediatrics and Child Health at the University of the Free State (UFS) in collaboration with Medi-Clinic, are hosting a Rose Ball in aid of children and babies with serious diseases and special needs.

The Bloemfontein public should get ready for one of the most magnificent events ever held in the city.

The Rose Ball promises to offer an evening of glamour, elegance and beauty which will make it an unforgettable and unique event. The Department aims to make the Rose Ball an annual event to which the Bloemfontein public can look forward to with expectation.

“Excellent food and wine, a 35 man symphony orchestra and of course a magical setting awaits those who attend the Rose Ball. We will do everything possible to make guests feel special, so that they return to the Rose Ball year after year. In this way, we can ensure an annual income from this event for children and babies who are very ill and need specialised care,” said Prof. André Venter, Head of the Department of Paediatrics and Child Health.

The Department of Paediatrics and Child Health at the UFS is responsible for the tertiary care, that is highly specialised care, of around 1 000 000 children in the Free State, Northern Cape, North-West, Eastern Cape and Lesotho. Approximately 13 000 out-patients are treated at the Universitas and Pelonomi Hospitals annually. Children who suffer from cancer, heart disease, neurological disease and endocrinological and gastro-enterological conditions are treated. The Department is also responsible for children who need intensive care and children with contagious diseases. In addition, there is a large neonatal unit where prematurely born babies are treated.

The level of health care needed to treat these children and babies, necessitate highly specialised equipment and knowledge. However, it is not always possible to replace or upgrade equipment, due to the lack of much-needed funds. That is why a fund was created within the Department to satisfy the need for funds. The Rose Ball promises to eventually give a vital boost to the fund that will go a long way toward providing in the special healthcare needs of these patients.

The Rose Ball is made possible thanks to the support of Medi-Clinic.

“Medi-Clinic is honoured to be involved in this great effort and in this way take hands with the Department of Paediatrics and Child Health at the UFS. There are so many children with life-threatening diseases today and we cannot afford to be uninvolved in any effort to make life better and easier for these children. We at Medi-Clinic, as a private sector company, look forward to establishing a long-term commitment with the Department of Paediatrics and Child Health,” said Mr Sakkie van der Merwe, Hospital Manager of Bloemfontein Medi-Clinic.

Only a limited number of tables are still available for the Rose Ball. Tickets cost R500 per person or R5 000 per table of 10 people.

Those who are interested can contact Ms Ilse Olivier at 051-4012415 or Ms Adele van Aswegen at 051-4013535 for more information.

Media release
Issued by:  Lacea Loader
   Media Representative
   Tel: (051) 401-2584
   Cell: 083 645 2454
   E-mail: loaderl.stg@mail.uovs.ac.za
8 September 2005

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