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25 June 2019 | Story Leonie Bolleurs | Photo Barend Nagel
Marnus du Plooy
Marnus du Plooy, recipient of a Fulbright Scholarship, will depart for the Duke University in Durham, North Carolina, in August to complete a doctoral degree.
Marnus du Plooy will receive his master’s degree at the University of the Free State’s Winter Graduation Ceremony.

After completing his BSc degree in Microbiology, he discovered a passion for this field of research and enrolled for postgraduate studies in the Department of Microbial, Biochemical and Food Biotechnology at the UFS.

During his master’s, Du Plooy focused on the pathogenic yeasts, Cryptococcus neoformans and a related species, C. deneoformans.

Passion for science instilled at a young age

His passion for this field comes from a young age. “Both my parents were Science teachers and they instilled a love for Science in me. At school, I enjoyed the Science subjects the most and usually obtained my highest marks in these,” Du Plooy said. 

The pathogenic yeasts studied by Du Plooy, Cryptococcus neoformans and the sister species, C. deneoformans, often cause meningitis in immunocompromised individuals, such as in people living with HIV/Aids.

He pointed out: “Infection caused by these yeasts is right on the heels of TB as the second largest killer of HIV-positive patients in sub-Saharan Africa. The focus of my master’s project was to investigate new ways in which genes can be ‘switched off’ in these yeasts in order to study the role of the genes in virulence. Doing so could help to identify new drug targets for the treatment of this form of meningitis in subsequent studies.”

Expanding his international footprint

Although Du Plooy received his master’s degree from the UFS, he grabbed the opportunity to study abroad with both hands. He applied for and received a Fulbright scholarship from the Fulbright Foreign Student Programme, giving him the opportunity to study in the US.

“I did not expect to get very far with the application, as very few candidates are selected each year. I was very lucky to receive a Fulbright scholarship and an admission offer from Duke University for PhD studies in Microbiology,” said Du Plooy.

He hopes to continue with research on Cryptococcus and to contribute to improving the lives of HIV/Aids patients. “I have always been interested in pharmaceutical and medical research and noticed a need for better cryptococcal treatments, especially in sub-Saharan Africa. Cryptococcal meningitis is a neglected disease which claims more than 600 000 lives worldwide every year. The current treatment options are several decades old, with some only available in well-resourced areas.”

Du Plooy will depart for the US in August. “The duration of the degree is four to five years, where-after I will return to South Africa to apply what I have learned at home.”

News Archive

Official opening: UFS earmarks R10-million to support national priorities
2006-02-06

 

The University of the Free State (UFS) is to align key areas of its academic and research efforts with national priorities through the introduction of five strategic clusters which would be funded by seedmoney of R10-million in 2006.

Speaking at the Official Opening of the UFS on Friday (3 February 2006), the Rector and Vice-Chancellor, Prof Frederick Fourie, said the academic and research work that will be done in the five strategic clusters would contribute to the development of Mangaung, the Free State, South Africa and Africa.

 “It makes sense to concentrate the university’s human resources, our infrastructure, financial resources and intellectual expertise to ensure that the UFS makes a contribution to the country and the African continent,” Prof Fourie said.

“Strategic clusters will be organised on the basis that these areas of knowledge could become in the short term the flagships of the UFS, meaning those areas where the university currently has or in the very near future is likely to have some competitive advantage,” Prof Fourie said.

According to Prof Fourie, this strategic-cluster approach will be in line with the approach being designed by the National Research Foundation (NRF) to take national priorities into account and would enhance the quality of scholarship at the UFS.

The five strategic areas in which research and academic investment at the UFS will be clustered are the following:

Enabling technologies / Technology for the future;
Food production, quality and food security for Africa;
Development;
Social transformation;
Water resource and ecosystem management;

“Such strategic clusters are understood not only as research areas but as areas that also encompass strong undergraduate and particularly postgraduate teaching and a potentially solid scientific basis for service learning and community service research,” Prof Fourie said.

Within each of these clusters specific niche areas will be identified. Clusters could focus on one or more aspects of a particular discipline or could involve more than one discipline in researching a particular issue.

He said not all academic work and research being done at the UFS would be clustered in this way. Sufficient resources and support have been put in place for general research excellence in the past five years.

“Some of the spin-offs can have an important impact on industrial development, for example in the chemicals industry and may also create a basis for cooperation with provincial, national and international partners,” he said. 

Media release
Issued by: Lacea Loader
Media Representative
Tel:   (051) 401-2584
Cell:  083 645 2454
E-mail:  loaderl.stg@mail.uovs.ac.za
5 February 2006

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