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25 June 2019 | Story Leonie Bolleurs | Photo Barend Nagel
Marnus du Plooy
Marnus du Plooy, recipient of a Fulbright Scholarship, will depart for the Duke University in Durham, North Carolina, in August to complete a doctoral degree.

Marnus du Plooy will receive his master’s degree at the University of the Free State’s Winter Graduation Ceremony.

After completing his BSc degree in Microbiology, he discovered a passion for this field of research and enrolled for postgraduate studies in the Department of Microbial, Biochemical and Food Biotechnology at the UFS.

During his master’s, Du Plooy focused on the pathogenic yeasts, Cryptococcus neoformans and a related species, C. deneoformans.

Passion for science instilled at a young age

His passion for this field comes from a young age. “Both my parents were Science teachers and they instilled a love for Science in me. At school, I enjoyed the Science subjects the most and usually obtained my highest marks in these,” Du Plooy said. 

The pathogenic yeasts studied by Du Plooy, Cryptococcus neoformans and the sister species, C. deneoformans, often cause meningitis in immunocompromised individuals, such as in people living with HIV/Aids.

He pointed out: “Infection caused by these yeasts is right on the heels of TB as the second largest killer of HIV-positive patients in sub-Saharan Africa. The focus of my master’s project was to investigate new ways in which genes can be ‘switched off’ in these yeasts in order to study the role of the genes in virulence. Doing so could help to identify new drug targets for the treatment of this form of meningitis in subsequent studies.”

Expanding his international footprint

Although Du Plooy received his master’s degree from the UFS, he grabbed the opportunity to study abroad with both hands. He applied for and received a Fulbright scholarship from the Fulbright Foreign Student Programme, giving him the opportunity to study in the US.

“I did not expect to get very far with the application, as very few candidates are selected each year. I was very lucky to receive a Fulbright scholarship and an admission offer from Duke University for PhD studies in Microbiology,” said Du Plooy.

He hopes to continue with research on Cryptococcus and to contribute to improving the lives of HIV/Aids patients. “I have always been interested in pharmaceutical and medical research and noticed a need for better cryptococcal treatments, especially in sub-Saharan Africa. Cryptococcal meningitis is a neglected disease which claims more than 600 000 lives worldwide every year. The current treatment options are several decades old, with some only available in well-resourced areas.”

Du Plooy will depart for the US in August. “The duration of the degree is four to five years, where-after I will return to South Africa to apply what I have learned at home.”

News Archive

Machinery and equipment to the value of R6 million acquired by UFS Instrumentation Division
2015-07-02

Photo: Supplied

At an information session held on the Bloemfontein Campus, the Instrumentation Division in the Faculty of Natural and Agricultural Sciences at the University of the Free State (UFS) introduced its new Computer Numeral Control (CNC) machines to the value of R6 million.

Initially, the primary aim of the Instrumentation workshop was to design, produce, and maintain special research equipment which is unavailable on the market, mainly for academic departments. The small-scale production focused on producing support material and equipment for research work.

However, with new equipment and machinery the Division now also can deliver a service to corporate companies and external associates.
 
The CNC machines include a 5-axis Vertical Machining Centre from Haas imported from America. This is one of only four in South Africa, with two in Johannesburg and one in Cape Town.  The lathe makes it possible to produce sophisticated parts, which were previously cumbersome and difficult to make. The machines also cover a wide spectrum in the mechanical field such as the the FLOW Water Jet, which cuts a wide variety of material ranging from titanium to wood without utilising heat, thus saving electricity. This makes it possible to cut a wide variety of materials.

With the new machinery now available, the Instrumentation Division is able to perform high quality and quantity production with precision.

“The advantage of the machinery is that it stimulates production, and is much faster and more accurate than the conventional way of doing things,” said Pieter Botes, Head of the Division.

Botes explained that, by having students and professional artisans at the university design and manufacture equipment, costs are reduced when compared with the expensive nature of equipment and tools found in the market. In addition, “the machines broaden the scope of research conducted” said Botes. The technical dynamics of the machinery advances the scientific knowledge needed to operate it, so bridging the gap between theory and practice.

The Central University of Technology, Signs Division Bloemfontein, Product Development Technology Station (PDTS), Maizey’s, and Knottco Truckparts are some of the university’s trade partners.

The workshop collaborates with the Chemistry, Physics, Microbiology, Botany, Agriculture, and Electronics departments, as well as the Institute of Groundwater Studies at the UFS, and others. These departments receive services in the form of pipette stands, containers for test tubes, bottles, laboratory trolleys, stands for cadavers for Anatomy, pump repairs, stainless steel bailers, filaments, and heaters.

The Instrumentation Division is, therefore, a vital support unit for the Faculty of Natural and Agricultural Sciences as well as the university at large.

Companies, institutions, or individuals who need the Division’s expertise may contact Pieter Botes on botespds@ufs.ac.za.

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