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Fulbright scholar wants to improve lives of HIV/Aids patients

25 June 2019 | Story Leonie Bolleurs | Photo Barend Nagel

Marnus du Plooy will receive his master’s degree at the University of the Free State’s Winter Graduation Ceremony.

After completing his BSc degree in Microbiology, he discovered a passion for this field of research and enrolled for postgraduate studies in the Department of Microbial, Biochemical and Food Biotechnology at the UFS.

During his master’s, Du Plooy focused on the pathogenic yeasts, Cryptococcus neoformans and a related species, C. deneoformans.

Passion for science instilled at a young age

His passion for this field comes from a young age. “Both my parents were Science teachers and they instilled a love for Science in me. At school, I enjoyed the Science subjects the most and usually obtained my highest marks in these,” Du Plooy said.

The pathogenic yeasts studied by Du Plooy, Cryptococcus neoformans and the sister species, C. deneoformans, often cause meningitis in immunocompromised individuals, such as in people living with HIV/Aids.

He pointed out: “Infection caused by these yeasts is right on the heels of TB as the second largest killer of HIV-positive patients in sub-Saharan Africa. The focus of my master’s project was to investigate new ways in which genes can be ‘switched off’ in these yeasts in order to study the role of the genes in virulence. Doing so could help to identify new drug targets for the treatment of this form of meningitis in subsequent studies.”

Expanding his international footprint

Although Du Plooy received his master’s degree from the UFS, he grabbed the opportunity to study abroad with both hands. He applied for and received a Fulbright scholarship from the Fulbright Foreign Student Programme, giving him the opportunity to study in the US.

“I did not expect to get very far with the application, as very few candidates are selected each year. I was very lucky to receive a Fulbright scholarship and an admission offer from Duke University for PhD studies in Microbiology,” said Du Plooy.

He hopes to continue with research on Cryptococcus and to contribute to improving the lives of HIV/Aids patients. “I have always been interested in pharmaceutical and medical research and noticed a need for better cryptococcal treatments, especially in sub-Saharan Africa. Cryptococcal meningitis is a neglected disease which claims more than 600 000 lives worldwide every year. The current treatment options are several decades old, with some only available in well-resourced areas.”

Du Plooy will depart for the US in August. “The duration of the degree is four to five years, where-after I will return to South Africa to apply what I have learned at home.”

News Archive

Mandela statues and the issue of public representation

2015-09-04

Prof Grant Parker, Associate Professor of Classics and Co-Director of the Centre for African Studies at Stanford University, USA, presented a public lecture on the Bloemfontein Campus on 27 August 2015, in which he explored the topic of ”Memorialising Mandela after Rhodes Must Fall”. What stories do the multitude of Mandela statues tell us about the man? Our society? Ourselves? These were some of the questions Prof Parker addressed during his lecture.

Paradoxes
Prof Parker discussed some of the paradoxes presented by the Mandela statues. The huge 9m high Mandela statue at the Union Buildings in Pretoria does not necessarily reflect his humility. Iconic statues strewn across the world do not reveal Madiba’s appeal. “Madiba’s charm,” Prof Parker said, “was all about his ability to relate to people of very different backgrounds. People who were his enemies would – to their surprise – find a humanity they were not expecting. It’s very hard to reconcile that with the colossal statues.”

Rhodes Must Fall
On the topic of the Rhodes Must Fall campaign, Prof Parker said that “the debates around it seem to express the frustration of deepening equality in general and lack of demographic change.” He also believes that, although the campaign centres on statues, there are much deeper issues at play that need to be addressed.

Artists should be part of the conversation
Prof Parker also advocated that artists’ voices should be incorporated into the creative processes of public art. “There is a much greater need for creative artists,” he concluded, “to be part of conversations, not only about what we as South Africans want to commemorate, but how we do that. I would very strongly suggest that this be done by non-figural representations.”

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