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25 June 2019 | Story Leonie Bolleurs | Photo Barend Nagel
Marnus du Plooy
Marnus du Plooy, recipient of a Fulbright Scholarship, will depart for the Duke University in Durham, North Carolina, in August to complete a doctoral degree.

Marnus du Plooy will receive his master’s degree at the University of the Free State’s Winter Graduation Ceremony.

After completing his BSc degree in Microbiology, he discovered a passion for this field of research and enrolled for postgraduate studies in the Department of Microbial, Biochemical and Food Biotechnology at the UFS.

During his master’s, Du Plooy focused on the pathogenic yeasts, Cryptococcus neoformans and a related species, C. deneoformans.

Passion for science instilled at a young age

His passion for this field comes from a young age. “Both my parents were Science teachers and they instilled a love for Science in me. At school, I enjoyed the Science subjects the most and usually obtained my highest marks in these,” Du Plooy said. 

The pathogenic yeasts studied by Du Plooy, Cryptococcus neoformans and the sister species, C. deneoformans, often cause meningitis in immunocompromised individuals, such as in people living with HIV/Aids.

He pointed out: “Infection caused by these yeasts is right on the heels of TB as the second largest killer of HIV-positive patients in sub-Saharan Africa. The focus of my master’s project was to investigate new ways in which genes can be ‘switched off’ in these yeasts in order to study the role of the genes in virulence. Doing so could help to identify new drug targets for the treatment of this form of meningitis in subsequent studies.”

Expanding his international footprint

Although Du Plooy received his master’s degree from the UFS, he grabbed the opportunity to study abroad with both hands. He applied for and received a Fulbright scholarship from the Fulbright Foreign Student Programme, giving him the opportunity to study in the US.

“I did not expect to get very far with the application, as very few candidates are selected each year. I was very lucky to receive a Fulbright scholarship and an admission offer from Duke University for PhD studies in Microbiology,” said Du Plooy.

He hopes to continue with research on Cryptococcus and to contribute to improving the lives of HIV/Aids patients. “I have always been interested in pharmaceutical and medical research and noticed a need for better cryptococcal treatments, especially in sub-Saharan Africa. Cryptococcal meningitis is a neglected disease which claims more than 600 000 lives worldwide every year. The current treatment options are several decades old, with some only available in well-resourced areas.”

Du Plooy will depart for the US in August. “The duration of the degree is four to five years, where-after I will return to South Africa to apply what I have learned at home.”

News Archive

UFS professor receives international recognition for exceptional ethical values
2015-10-02

“You grow so fond of them,” Prof André Venter,
Head: Department of Paediatrics and Child Health,
says while doing his rounds with patients.
Prof Venter recently received the award for health professions
from the international organisation, Unashamedly Ethical.

“You are such a pretty baby,” Prof André Venter, Head: Department of Paediatrics and Child Health at the University of the Free State, whispers to a baby lying stretched out in her neonatal cradle.

He uses his fingertips to free her legs and arms carefully from the monitors and wires attached to her.

“See how much you have grown,” he says, tapping with his finger on her file. 1.2 kg - her weight indicates. 

In one of the other children’s wards, he joins a mother sitting with her sick baby. Speaking about the baby’s operation coming up within the next few months, he gives her an encouraging pat on the shoulder.

He visits yet another mother who is practising kangaroo care on her baby, and asks to hold the baby for a while.

“Gosh, you’re so nice and warm, let doctor hold you for a while,” he says, hugging the premature baby to his chest.

Prof Venter greets and thanks the nursing staff at the end of his ward rounds.

“Everything is not always good, but one can try to plan for the future from the challenges,” he says. “One should never concentrate on the immediate problem too much, but lift the morale of those using our services, those providing the services, and those who come here for training.”

It is this kind of passion and outlook that earned Prof Venter an ethical award from the international organisation, Unashamedly Ethical. The award, which was made in the health professions category, recognises doctors for exceptional ethical values and for going the extra mile in alleviating the suffering of humanity.

“I am humbled at being honoured for something I see as my passion and actually take for granted. I am also touched that people from outside noticed and nominated me for this,” he says.

He talks about his young patients again: “I learn so much from them each day. Children are so resistant to negative things. I grow so fond of them that I forget they have to go home some time.”

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