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Fulbright scholar wants to improve lives of HIV/Aids patients

25 June 2019 | Story Leonie Bolleurs | Photo Barend Nagel

Marnus du Plooy will receive his master’s degree at the University of the Free State’s Winter Graduation Ceremony.

After completing his BSc degree in Microbiology, he discovered a passion for this field of research and enrolled for postgraduate studies in the Department of Microbial, Biochemical and Food Biotechnology at the UFS.

During his master’s, Du Plooy focused on the pathogenic yeasts, Cryptococcus neoformans and a related species, C. deneoformans.

Passion for science instilled at a young age

His passion for this field comes from a young age. “Both my parents were Science teachers and they instilled a love for Science in me. At school, I enjoyed the Science subjects the most and usually obtained my highest marks in these,” Du Plooy said.

The pathogenic yeasts studied by Du Plooy, Cryptococcus neoformans and the sister species, C. deneoformans, often cause meningitis in immunocompromised individuals, such as in people living with HIV/Aids.

He pointed out: “Infection caused by these yeasts is right on the heels of TB as the second largest killer of HIV-positive patients in sub-Saharan Africa. The focus of my master’s project was to investigate new ways in which genes can be ‘switched off’ in these yeasts in order to study the role of the genes in virulence. Doing so could help to identify new drug targets for the treatment of this form of meningitis in subsequent studies.”

Expanding his international footprint

Although Du Plooy received his master’s degree from the UFS, he grabbed the opportunity to study abroad with both hands. He applied for and received a Fulbright scholarship from the Fulbright Foreign Student Programme, giving him the opportunity to study in the US.

“I did not expect to get very far with the application, as very few candidates are selected each year. I was very lucky to receive a Fulbright scholarship and an admission offer from Duke University for PhD studies in Microbiology,” said Du Plooy.

He hopes to continue with research on Cryptococcus and to contribute to improving the lives of HIV/Aids patients. “I have always been interested in pharmaceutical and medical research and noticed a need for better cryptococcal treatments, especially in sub-Saharan Africa. Cryptococcal meningitis is a neglected disease which claims more than 600 000 lives worldwide every year. The current treatment options are several decades old, with some only available in well-resourced areas.”

Du Plooy will depart for the US in August. “The duration of the degree is four to five years, where-after I will return to South Africa to apply what I have learned at home.”

News Archive

Ivory Coast too dependent on UN to combat violence against women

2015-10-08

During the seminar presented by the Centre for
African Studies (CAS) at the University of the Free State
were, from the left: Thesipo Machabaphala, student in
Gender Studies; Prof Heidi Hudson, Head of CAS;
Dr Peace Medie from the University of Ghana,
guest speaker; and Sesi Mahlobogoane, student in
Gender Studies.

The Ivory Coast is still too dependent on the work of the United Nations (UN) to combat violence against women in the country. There is much talk about ways to address the problem, but the government is still not acting quickly and effectively enough to make a difference in the long term.

These were some of the findings by Dr Peace Medie from the University of Ghana, guest speaker during a seminar series held by the Centre for Africa Studies (CAS) on the Bloemfontein Campus of the University of the Free State on 1 October 2015.

Dr Medie presented a seminar for students in the Gender Studies programme entitled Women, Security, and Justice: a Study of the Ivorian State’s Response to Violence against Women. Prof Heidi Hudson, Head of CAS in the Faculty of the Humanities at the UFS, facilitated the seminar.

For the sake of internationalisation, the CAS often presents guest speakers from outside South Africa to address its students. In addition , Dr Medie is from Africa.

According to Dr Medie, who conducted some 150 interviews during her research over two years, there was a shortage of resources in the Ivory Coast. This is also the case in several other African countries previously involved in war.

She believes the Ivory Coast should do more to combat violence against women successfully.

She said the UN had a great influence on the way people, especially the police, were thinking about the problem - which included sexual violence against women.

“The UN will not be there forever,” Dr Medie said.

“If response depended only on the influence of an international organisation, what would happen when the UN leaves?”

According to Dr Medie, a shortage of active women’s organisations also had a role to play. She was of the opinion that these organisations should put more pressure on the government to ensure better treatment for women.

“Local organisations are needed because it is not sustainable to depend only on the work of the UN.”

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