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25 June 2019 | Story Leonie Bolleurs | Photo Barend Nagel
Marnus du Plooy
Marnus du Plooy, recipient of a Fulbright Scholarship, will depart for the Duke University in Durham, North Carolina, in August to complete a doctoral degree.

Marnus du Plooy will receive his master’s degree at the University of the Free State’s Winter Graduation Ceremony.

After completing his BSc degree in Microbiology, he discovered a passion for this field of research and enrolled for postgraduate studies in the Department of Microbial, Biochemical and Food Biotechnology at the UFS.

During his master’s, Du Plooy focused on the pathogenic yeasts, Cryptococcus neoformans and a related species, C. deneoformans.

Passion for science instilled at a young age

His passion for this field comes from a young age. “Both my parents were Science teachers and they instilled a love for Science in me. At school, I enjoyed the Science subjects the most and usually obtained my highest marks in these,” Du Plooy said. 

The pathogenic yeasts studied by Du Plooy, Cryptococcus neoformans and the sister species, C. deneoformans, often cause meningitis in immunocompromised individuals, such as in people living with HIV/Aids.

He pointed out: “Infection caused by these yeasts is right on the heels of TB as the second largest killer of HIV-positive patients in sub-Saharan Africa. The focus of my master’s project was to investigate new ways in which genes can be ‘switched off’ in these yeasts in order to study the role of the genes in virulence. Doing so could help to identify new drug targets for the treatment of this form of meningitis in subsequent studies.”

Expanding his international footprint

Although Du Plooy received his master’s degree from the UFS, he grabbed the opportunity to study abroad with both hands. He applied for and received a Fulbright scholarship from the Fulbright Foreign Student Programme, giving him the opportunity to study in the US.

“I did not expect to get very far with the application, as very few candidates are selected each year. I was very lucky to receive a Fulbright scholarship and an admission offer from Duke University for PhD studies in Microbiology,” said Du Plooy.

He hopes to continue with research on Cryptococcus and to contribute to improving the lives of HIV/Aids patients. “I have always been interested in pharmaceutical and medical research and noticed a need for better cryptococcal treatments, especially in sub-Saharan Africa. Cryptococcal meningitis is a neglected disease which claims more than 600 000 lives worldwide every year. The current treatment options are several decades old, with some only available in well-resourced areas.”

Du Plooy will depart for the US in August. “The duration of the degree is four to five years, where-after I will return to South Africa to apply what I have learned at home.”

News Archive

What did they learn at Stanford University?
2015-11-04

    

Members of the cohort with the
Vice-Chancellor and Rector of the UFS,
Prof Jonathan Jansen

Every year, since 2012, six second-year Kovsies are selected to take part in the elite Stanford Sophomore College Programme at the prestigious Stanford University in the United States. The University of the Free State and Oxford University are the only non-Stanford members of this exclusive course.

From 31 August to 15 September 2015, Farzaana Adam, Cornel Vermaak, Precious Mokwala, Tristan Van Der Spuy, Anje Venter, and Naushad Mayat undertook a three-week long academic exploration of multidisciplinary topics. These students attended seminars aligned with their respective fields of study from which they accumulated a wealth of knowledge.

This year’s cohort reflects on what they learned at Stanford University:

The significance of analyzing technology

One of the key points gathered by Farzaana Adam from the seminar, ‘Great Ideas in Computer Science’, was the necessity not to approach technology at face value. “Computer science goes beyond the technological products and social networks. By analysing the concepts underlying these technologies, many discoveries which have benefitted many fields of study have been made possible.”

Critical thinking in Arts and Science


“By combining different fields of study, one can obtain a greater perspective on the relevant fields,” said Cornel Vermaak, about what he garnered from a seminar titled ‘An Exploration of Art Materials: An intersection between the Arts and Science’. “This greater perspective enables one to evaluate problems critically,” he added.

Visual media substitutes oral narratives

“We were also taught different ways in which to interpret images, and how images influence society. Photography is a way to tell a story without actually having to say anything,” reflected Precious Mokwala, on ‘Photography: truth or fiction’

A lesson in business economics


Tristan Van Der Spuy received pointers pertaining to the stock exchange market    in ‘A Random Walk Down Wall Street’. “We looked at stock markets, and what influenced the stock prices of multiple companies, taking note of what should be looked at when investing in a company.”

Race relations and representation

‘The New Millenium Mix: Crossings between Race and Culture’ exposed Anje Venter to a global perspective on identity. “We explored the new generation of people that have mixed races and cultures, and how they are depicted in media and art.  We analysed the discrepancies and stereotypes of these depictions through film, novel, and short story studies, as well as through field trips to museums and art exhibitions.”

Overcoming the HIV/AIDS endemic


Naushad Mayat realised that “more teamwork and transparency between governments, chemists, social workers, and clinicians will be required for us to stem the flow [of HIV/AIDS],” in view of what he learned in a seminar on ‘HIV/AIDS: A Response to the AIDS Epidemic in the Bay Area’. “It is a daunting task. For the current generation of youth to tackle this epidemic now, we must stand together and be counted,” he added.



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