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Fulbright scholar wants to improve lives of HIV/Aids patients

25 June 2019 | Story Leonie Bolleurs | Photo Barend Nagel

Marnus du Plooy will receive his master’s degree at the University of the Free State’s Winter Graduation Ceremony.

After completing his BSc degree in Microbiology, he discovered a passion for this field of research and enrolled for postgraduate studies in the Department of Microbial, Biochemical and Food Biotechnology at the UFS.

During his master’s, Du Plooy focused on the pathogenic yeasts, Cryptococcus neoformans and a related species, C. deneoformans.

Passion for science instilled at a young age

His passion for this field comes from a young age. “Both my parents were Science teachers and they instilled a love for Science in me. At school, I enjoyed the Science subjects the most and usually obtained my highest marks in these,” Du Plooy said.

The pathogenic yeasts studied by Du Plooy, Cryptococcus neoformans and the sister species, C. deneoformans, often cause meningitis in immunocompromised individuals, such as in people living with HIV/Aids.

He pointed out: “Infection caused by these yeasts is right on the heels of TB as the second largest killer of HIV-positive patients in sub-Saharan Africa. The focus of my master’s project was to investigate new ways in which genes can be ‘switched off’ in these yeasts in order to study the role of the genes in virulence. Doing so could help to identify new drug targets for the treatment of this form of meningitis in subsequent studies.”

Expanding his international footprint

Although Du Plooy received his master’s degree from the UFS, he grabbed the opportunity to study abroad with both hands. He applied for and received a Fulbright scholarship from the Fulbright Foreign Student Programme, giving him the opportunity to study in the US.

“I did not expect to get very far with the application, as very few candidates are selected each year. I was very lucky to receive a Fulbright scholarship and an admission offer from Duke University for PhD studies in Microbiology,” said Du Plooy.

He hopes to continue with research on Cryptococcus and to contribute to improving the lives of HIV/Aids patients. “I have always been interested in pharmaceutical and medical research and noticed a need for better cryptococcal treatments, especially in sub-Saharan Africa. Cryptococcal meningitis is a neglected disease which claims more than 600 000 lives worldwide every year. The current treatment options are several decades old, with some only available in well-resourced areas.”

Du Plooy will depart for the US in August. “The duration of the degree is four to five years, where-after I will return to South Africa to apply what I have learned at home.”

News Archive

Meet the person behind the new #FaceOfFacebook

2016-05-19

Reuben “R” Davids

The votes have been counted, and we have a winner! After much excitement and a fairly close contest, Reuben “R” Davids emerged victorious from the top five contestants selected by our panel of judges. We chatted with the vibrant and enthusiastic Mr Davids to get a sense of the person who will be our Facebook ambassador for the next year.

What does the “R” stand for?

“Interestingly, some also know me as Vuyo. It's not a name on my birth certificate or anything; I just really like it. And I also coincidentally found out that it means “joy/happiness”, and I do enjoy being happy.”

What is your field of study, and how far along are you?

“I am pursuing a career in the economics field as a third-year BCom Accounting student in the Faculty of Economic and Management Sciences here at the University of the Free State.”

Are you originally from Bloemfontein?

“Yes, born and bred. I've been a Bloem Kid since day one.”

How is it that you ended up here, studying at the UFS?

“The UFS has always been one of my favourite universities. During my high school period, I was constantly exposed to people from my neighbourhood as well as schoolmates who performing excellently here at UFS, and it didn't go unnoticed. So I have always been drawn to the prestige that UFS carries.”

Which residence are you in, and what do you enjoy most about res life?

“I currently stay at home with the family, but for my first 2 years of study I resided at ConLaurês. What I enjoyed the most about res life is the freedom and independence that you get. It also enables one to participate in campus life much easier. It actually helps one grow and mature into the adult you're supposed to become with all the challenges and responsibilities that you're faced with.”

What do you hope to accomplish during your term as the #FaceOfFacebook?

“I enjoy the art of presenting (as well as being an MC), and being the #FaceOfFacebook will enable me to exercise that skill. Also, my interaction skills will be exercised. That being said, I would like to have those skills developed further by the end of my term as #FaceOfFacebook.”

What is your motivation in your studies, in taking part in this contest, and in life?

“I am an adrenaline junkie. I like taking on challenge; so what I normally do is I set a certain goal for myself and then take on the challenge to achieve that goal. That's my number one motivating factor. And I think I'm also inspired by the failures and successes of myself and of those around me.”

Reuben has already been featured in a #PeopleOfKovsies post on Facebook, and appeared in his first Facebook video covering the Open Day on our Bloemfontein Campus.

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