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Fulbright scholar wants to improve lives of HIV/Aids patients

25 June 2019 | Story Leonie Bolleurs | Photo Barend Nagel

Marnus du Plooy will receive his master’s degree at the University of the Free State’s Winter Graduation Ceremony.

After completing his BSc degree in Microbiology, he discovered a passion for this field of research and enrolled for postgraduate studies in the Department of Microbial, Biochemical and Food Biotechnology at the UFS.

During his master’s, Du Plooy focused on the pathogenic yeasts, Cryptococcus neoformans and a related species, C. deneoformans.

Passion for science instilled at a young age

His passion for this field comes from a young age. “Both my parents were Science teachers and they instilled a love for Science in me. At school, I enjoyed the Science subjects the most and usually obtained my highest marks in these,” Du Plooy said.

The pathogenic yeasts studied by Du Plooy, Cryptococcus neoformans and the sister species, C. deneoformans, often cause meningitis in immunocompromised individuals, such as in people living with HIV/Aids.

He pointed out: “Infection caused by these yeasts is right on the heels of TB as the second largest killer of HIV-positive patients in sub-Saharan Africa. The focus of my master’s project was to investigate new ways in which genes can be ‘switched off’ in these yeasts in order to study the role of the genes in virulence. Doing so could help to identify new drug targets for the treatment of this form of meningitis in subsequent studies.”

Expanding his international footprint

Although Du Plooy received his master’s degree from the UFS, he grabbed the opportunity to study abroad with both hands. He applied for and received a Fulbright scholarship from the Fulbright Foreign Student Programme, giving him the opportunity to study in the US.

“I did not expect to get very far with the application, as very few candidates are selected each year. I was very lucky to receive a Fulbright scholarship and an admission offer from Duke University for PhD studies in Microbiology,” said Du Plooy.

He hopes to continue with research on Cryptococcus and to contribute to improving the lives of HIV/Aids patients. “I have always been interested in pharmaceutical and medical research and noticed a need for better cryptococcal treatments, especially in sub-Saharan Africa. Cryptococcal meningitis is a neglected disease which claims more than 600 000 lives worldwide every year. The current treatment options are several decades old, with some only available in well-resourced areas.”

Du Plooy will depart for the US in August. “The duration of the degree is four to five years, where-after I will return to South Africa to apply what I have learned at home.”

News Archive

Minister praises MUCPP initiative

2004-10-04

The Minister of Labour, Mr MMS Mdladlana, singled out the Mangaung University of the Free State Community Partnership Programme (MUCPP) for high praise during a conference at the MUCPP complex on 30 September 2004 .

“I am very pleased with what the partnership of different stakeholders can do and I thank all stakeholders for contributing to this initiative. This is the kind of energy that our country needs,” the minister told delegates to the conference.

He said the MUCPP was a very unusual and important partnership that is related directly to the mandate of government and supports two strategic objectives of government, namely halving poverty and halving unemployment.

The MUCPP was launched in 1991 as a partnership between the University of the Free State , the local community of Mangaung, local and provincial government and the private sector, in an effort to develop skills and contribute to fighting poverty.

Some of the existing projects of the MUCPP include:

Health centre (including a 24-hour maternity ward)
Dairy producing yoghurt and amasi
Sewing and knitting project
Indigenous food production (Tsa se tso)
Bakery
Bed and Breakfast accommodation
Etsa phapang (a hydroponic facility growing various vegetables)
Welding project
Low cost housing project
Sport and recreation facilities and programmes

According to the Minister, hundreds of young people, adult learners and people with disabilities have benefited from training and skills development and have become involved in carpentry, welding, painting, cleaning services, gardening and HIV / AIDS awareness programmes.

Minister Mdladlana said he was pleased that through partnerships with several Sector Education and Training Authorities (SETAs) which fall under the Department of Labour, the MUCPP could access hundreds of thousands of rands for such training and development.

“I can just salute those that have made it possible, and to encourage you to keep up the good work,” the minister said.

The MUCPP also provides a means for students of the UFS to render community service. The UFS was one of the first universities in South Africa to adopt a comprehensive community service policy in 2002. In terms of the policy, community service is integrated into curricula through service learning modules.

It is therefore of great importance that the UFS should support community sites such as the MUCPP where a holistic and integrated approach to mutual and reciprocal development of all partners is followed.

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