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25 June 2019 | Story Leonie Bolleurs | Photo Barend Nagel
Marnus du Plooy
Marnus du Plooy, recipient of a Fulbright Scholarship, will depart for the Duke University in Durham, North Carolina, in August to complete a doctoral degree.
Marnus du Plooy will receive his master’s degree at the University of the Free State’s Winter Graduation Ceremony.

After completing his BSc degree in Microbiology, he discovered a passion for this field of research and enrolled for postgraduate studies in the Department of Microbial, Biochemical and Food Biotechnology at the UFS.

During his master’s, Du Plooy focused on the pathogenic yeasts, Cryptococcus neoformans and a related species, C. deneoformans.

Passion for science instilled at a young age

His passion for this field comes from a young age. “Both my parents were Science teachers and they instilled a love for Science in me. At school, I enjoyed the Science subjects the most and usually obtained my highest marks in these,” Du Plooy said. 

The pathogenic yeasts studied by Du Plooy, Cryptococcus neoformans and the sister species, C. deneoformans, often cause meningitis in immunocompromised individuals, such as in people living with HIV/Aids.

He pointed out: “Infection caused by these yeasts is right on the heels of TB as the second largest killer of HIV-positive patients in sub-Saharan Africa. The focus of my master’s project was to investigate new ways in which genes can be ‘switched off’ in these yeasts in order to study the role of the genes in virulence. Doing so could help to identify new drug targets for the treatment of this form of meningitis in subsequent studies.”

Expanding his international footprint

Although Du Plooy received his master’s degree from the UFS, he grabbed the opportunity to study abroad with both hands. He applied for and received a Fulbright scholarship from the Fulbright Foreign Student Programme, giving him the opportunity to study in the US.

“I did not expect to get very far with the application, as very few candidates are selected each year. I was very lucky to receive a Fulbright scholarship and an admission offer from Duke University for PhD studies in Microbiology,” said Du Plooy.

He hopes to continue with research on Cryptococcus and to contribute to improving the lives of HIV/Aids patients. “I have always been interested in pharmaceutical and medical research and noticed a need for better cryptococcal treatments, especially in sub-Saharan Africa. Cryptococcal meningitis is a neglected disease which claims more than 600 000 lives worldwide every year. The current treatment options are several decades old, with some only available in well-resourced areas.”

Du Plooy will depart for the US in August. “The duration of the degree is four to five years, where-after I will return to South Africa to apply what I have learned at home.”

News Archive

Boyden observatory celebrates its achievements
2004-10-05

The red carpet will be rolled out and champagne glasses filled tonight when the Boyden Observatory outside Bloemfontein will launch the first phase of the new science centre.

This phase, which was completed earlier this year, consists of a new auditorium, reception area and paths which connect educational visiting points on the Boyden terrain.

“Over the past two years the Boyden Observatory has been re-sited as a research, educational and public facility. The new facilities are now being utilised for educational and public programmes. The 1,5m Boyden telescope has also recently been upgraded and is used for research purposes,” says Dr Matie Hoffman from the University of the Free State’s (UFS) Department of Physics, who is responsible for the management of the centre.

“The Boyden Observatory is a unique facility of the UFS - we are one of the few universities in the world who has its own observatory,” says Dr Hoffman.

“The main purpose of the science centre is to create enthusiasm for science amongst the public. The centre also has a great educational function and focuses specifically on the improvement of the quality of science education in the Free State,” says Dr Hoffman.

Fund-raising for the planned second phase of the science centre, which will consist of interactive in- and outside exhibition areas, will also start tonight. “After the completion of the second phase the Boyden Observatory will probably become the most accessible and public-friendly observatory in the country and a great asset for the Free State Province,” says Dr Hoffman.

A small robotic telescope, which will be controlled from the University College Dublin in Ireland, will also be installed at the Boyden Observatory this year.

“Just as this year is a significant one for the UFS with its centenary celebrations, so it is also a significant one for the Boyden Observatory. The Harvard University in the United States of America started with the construction of the original 1,5 m telescope in its original form 100 years ago, the telescope was put in place at Boyden 70 years ago and Mr Uriah Boyden – the person who donated the money with which the Boyden Observatory was constructed, was born 200 years ago,” says Dr Hoffman.

The first phase of the science centre was built with funds sponsored by the AngloGold Fund, the Shuttleworth Foundation, the Charl van der Merwe Trust and the Lila Theron Trust. Donations from the Friends of Boyden Observatory and other individuals also contributed to the success of the project.

Those who are interested in educational tours of the science centre can contact Dr Hoffman at (051) 401-2322.

Media release
Issued by: Lacea Loader
Media Representative
Tel: (051) 401-2584
Cell: 083 645 2454
E-mail: loaderl.stg@mail.uovs.ac.za
5 October 2004

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