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22 March 2019 | Story Rulanzen Martin | Photo Stephen Collett
Prof Johann Rossouw Inaugural lecture
Prof Heidi Hudson, Dean of the Faculty of the Humanities; Prof Fani de Beer, Prof Rossouw’s mentor; Prof Johann Rossouw; and Dr Engela van Staden, Vice-Rector: Academic.

For Prof Johann Rossouw from the Department of Philosophy, the Naval Hill Planetarium – a digital planetarium on a hill in the centre of a modern city, was the perfect place to deliver his inaugural lecture titled, The soul of the academy.

The message of his inaugural lecture was on “the form adopted by the contemporary university, which is so focused on the quantitative that the qualitative is neglected. The focus on training is so strong that the university no longer pays attention to the education of students”.

Prof Rossouw referred to the soul of the academy as the highest in humanity, especially the part which cannot be counted. He also referred to the words of Blaise Pascal in the 17th century: “The heart has its reasons of which reason knows nothing”.

“Do we understand any of this in the contemporary university? And do we still remember the earliest origins from which the academy originated; that Philosophy is the mother discipline of all other disciplines, and how all contemporary disciplines form part of a bigger, coherent entity?” he asked.

The inaugural lecture took place on 28 February 2019. Prof Rossouw has a C2-rating from the National Research Foundation, and it is thanks to him, among other things, that the Department of Philosophy is the only South African Philosophy department with modernity studies as its main focus.

At the end of 2018, he was promoted to Professor of Philosophy at the University of the Free State (UFS), and currently he serves as acting Head of Department. “Due to Prof Rossouw’s involvement, among other things, research on African philosophy, critical theory, postcolonial thinking, and tradition and modernity is conducted in the department,” Prof Heidi Hudson (Dean: the Humanities) said.

Prof Rossouw started his formal training in Philosophy at the age of 12, and in 1991 he obtained a BA degree majoring in Philosophy and Psychology at the University of Pretoria, with distinction. He obtained his MA degree, a critical study of apartheid on the basis of Michel Foucault’s thinking, at Unisa in 1998. In 2002, he obtained his DEA in Philosophy at the University of Lyon 3 under the leadership of Régis Debray, and in 2013 his PHD on the theological trail in Bernard Stiegler’s thinking at Monsh University (Melbourne), under Michael Janover.

In 2016, he won a prize from the South African Academy for Science and Culture for one of the best Afrikaans humanity articles published in 2015.

 

News Archive

Nuclear Medicine on the forefront of cancer research
2017-07-10

Description: Nuclear Medicine on the forefront of cancer research Tags: Nuclear Medicine, cancer research, Dr Je’nine Horn-Lodewyk’s, tumour detection method, cancer, Department of Nuclear Medicine 

Dr Je’nine Horn-Lodewyk’s tumour detection method
could be the cost-effective breakthrough needed to decrease
the mortality rate in breast cancer patients.
Photo: Anja Aucamp

The field of Nuclear Medicine in South Africa and the rest of the world are expanding rapidly due to the development of hybrid cameras and new radiopharmaceuticals. These developments have a huge impact on the diagnosis and therapy of cancer.

The most advanced of these cameras, Positron emission tomography combined with normal CTs (PETCT), are not yet widely available in South Africa due to the cost of the cameras and the radiopharmaceuticals. A more cost-effective alternative can be of great benefit. To achieve this, the focus should be on developing new radiopharmaceuticals that can be used with the current cost-effective gamma cameras, according to University of the Free State researcher, Dr Je’nine Horn-Lodewyk from the Department of Nuclear Medicine.

Fluorodeoxyglucose (18F-FDG), a radiolabelled glucose analogue, is currently the radiopharmaceutical most commonly used in PET/CT imaging for mainly oncology indications. Although it is considered the gold standard for imaging in several malignancies, it does have certain disadvantages. An 18F-FDG PET/CT diagnostic imaging study can cost between R25 000 and R35 000 for a single patient in the private sector. The 18F-FDG is also more radioactive, which requires much stricter handling and shielding to avoid high radiation dosages to staff and patients.

Successful research potential innovative solution
In the search for the ideal radiopharmaceutical for tumour detection, the South African National Nuclear Energy Corporation (Necsa) developed a local synthesis process for ethylenedicysteine-deoxyglucose (EC-DG). EC-DG is also a glucose analogue similar to FDG. They succeeded in labelling the compound with Technetium-99-metastable-pertechnetate (99mTcO4-), the most common nuclear medicine isotope used for approximately 95% of nuclear medicine procedures, creating 99mTc-EC-DG.

In partnership with Dr Horn-Lodewyk, this compound was successfully used in various animal models and clinical scenarios, resulting in approval by the Medicine Control Council to use it in a human study. Research is also planned in order to investigate diagnostic accuracy in other cancers like lymphoma.  The end result of this research can produce a radiopharmaceutical that is cost effective, does not require the use of costly specialised equipment, has no significant side-effects, no special patient preparation, renders late imaging possible, and has decreased radiation risks.

Dr Horn-Lodewyk is grateful for the support of her mentor, Prof Anton Otto, as well as Dr Gert Engelbrecht, Head of the Department of Nuclear Medicine, Prof Jan Rijn Zeevaart from North-West University’s Preclinical Drug Development Platform and Necsa, and Judith Wagener from Necsa. This innovative research would also not have been possible without the financial assistance of Dr Glen Taylor and Eleanor van der Westhuizen in the Directorate of Research Development.

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