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13 March 2019 | Story Zama Feni | Photo Zama Feni
Career fair
UFS BCom (Marketing) student, Thandokazi Kiviet, who works part time for fellow master’s student Refilwe Xaba’s hair-product company, Glolooks, shows off their products to visitors at the Annual Careers Fair last week.

Budding student entrepreneurs from the University of the Free State presented their creative displays during the first part of the university’s 2019 Annual Careers Fair at the Callie Human Hall last week.

The first leg of the fair was in the Faculty of Economic and Management Sciences, with more than 15 companies exhibiting their products and explaining to students their business operations, career prospects, and employment opportunities.

Students’ construction business gets off the ground

Three ladies, Mannini Setai (master’s in Law), Refilwe Mogole (PhD in Chemistry), and Nthabiseng Molejane (honours in the Humanities) registered their company, Ahang Amalmagate Trading, in 2016 and have been operating since late 2017.

Mogole said they are currently operating from a backyard in Parys, but they have a manager on site who deals with the technical aspects of their business and runs the daily operations. 

“We managed to buy a brick-making machine, which enabled us to make up to 1 000 bricks per day; at this stage, we provide bricks to private homeowners,” she said.

The ladies said winning three competitions last year gave them a financial boost that aided them greatly; these included the Nampak Entrepreneurship Competition, the Free State Department of Economic, Small Business Development, Tourism and Environmental Affairs Tabalaza Pitching Programme, as well as the UFS Directorate for Research Development’s business pitching competition.

“As a result of these competitions, we managed to save some cash to buy ourselves a brick-making machine,” said Setai, adding that they are using social networks to market their product.

Hair-product business gives hope

Another student business stall was that of Glolooks – an emerging hair-products company established by UFS student, Refilwe Xaba, who has just finished her master’s programme in Entrepreneurship at the UFS. “The biggest challenge is access to the markets, but my business is doing fairly well here in Bloemfontein; our use of online media and social networks to market our products is keeping us there,” said Ms Xaba. She said she has just opened an ethnic hair salon in Westdene.

Taking it slowly, but surely

Another UFS student was Anet Matakala of Nettah Organics (Law degree) who makes organic products such as green tea, bath salts, chocolate coffee, cannabis butter, etc., from food-based ingredients. “It’s not an easy road, but step by step, we are getting there,” she said.

The last student was Keagan Nkwaira, who started a clothing company named ‘Weather’ last year. “What drove me to starting this venture was a passion for design and a need to raise cash. Business hasn’t been good so far, but I will have to find marketing initiatives that will get my work to the potential customers,” he said.


Career fairs benefit students

Head of Career Services, Belinda Janeke, said there will be four more career fairs catering for the Faculties of Law and Natural and Agricultural Sciences during the course of the year, and two general career fairs in May and August.

“The career fairs help to connect our students with the world of work, it helps to broaden the horizons for students because they can enquire about the products or services provided by the respective companies, and it can also create job and internship opportunities,” she said.  

News Archive

UFS study on cell development in top international science journal
2008-09-16

A study from the University of the Free State (UFS) on how the change in the packaging of DNA with cell development influenced the expression of genes, will be published in this week’s early edition of the prestigious international, peer-reviewed science journal, the Proceeding of the National Academy of Sciences of the USA (PNAS).

The PNAS journal has an impact factor of 10, which means that studies published in the journal are, on average, referred to by ten other scientific studies in a two year period. The South African Journal of Science, by comparison, has an impact factor of 0.7.

The UFS study, funded by the Wellcome Trust and the National Research Foundation (NRF), looked at how the change in the packaging of DNA with cell development influenced the expression of genes. It is very relevant to research on stem cells, an area of medicine that studies the possible use of undifferentiated cells to replace damaged tissue.

Prof. Hugh Patterton, of the Department of Microbial, Biochemical and Food Biotechnology at the UFS, who led the study, said: "We are extremely proud of this study. It was conceived in South Africa, it was performed in South Africa, the data were analysed in South Africa, and it was published from South Africa."

When a gene is expressed, the information encoded in the gene is used to manufacture a specific protein. In eukaryotes, which include humans, there is approximately 1m of DNA, containing the genes, in every cell. This length of DNA has to fit into a cell nucleus with a diameter of only about 10 micrometer. In order to fit the DNA into such a small volume, eukaryotic cells wrap their DNA onto successive protein balls, termed nucleosomes. Strings of nucleosomes, resembling a bead of pearls, is folded into a helix to form a chromatin fiber. The study from the UFS investigated how the binding of a specific protein, termed a linker histone, that binds to the length of DNA between nucleosomes, influenced the formation of the chromatin fiber and also the activity of genes.

"We found that the linker histone bound to chromatin in yeast, which we use as a model eukaryote, under conditions where virtually all the genes in the organism were inactive. It was widely believed that the binding of the linker histone caused the inactivation of genes. We studied the relationship between the amount of linker histone bound in the vicinity of each gene and the expression of that gene for all the genes in yeast, using genomic techniques. We made the surprising discovery that even through the linker histone preferentially bound to genes under conditions where the genes were shut off, this inactivation of genes was not caused by the binding of the linker histone and folding of the chromatin,” said Prof. Patterton.

He said: “Instead our data strongly suggested that the observed anti-correlation was due to the movement of enzymes along the DNA molecule, involved in processing the information in genes for the eventual manufacture of proteins. This movement of enzymes displaced the linker histones from the DNA. This finding now requires a rethink on aspects of how packaging of DNA influences gene activity."

Prof. Patterton said that his research group, using the Facility for Genomics and Proteomics as well as the Bioinformatics Node at the UFS, was currently busy with follow-up studies to understand how other proteins in nucleosomes affected the activities of genes, as well as with projects to understand how chemicals found in red wine and in green tea extended lifespan. "We are certainly having a marvelous time trying to understand the fundamental mechanisms of life, and the UFS is an exciting place to be if one was interested in studying life at the level of molecules," he said.


Media Release
Issued by: Lacea Loader
Assistant Director: Media Liaison
Tel: 051 401 2584
Cell: 083 645 2454
E-mail: loaderl.stg@ufs.ac.za  
18 September 2008
 

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