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24 May 2019 | Story Eloise Calitz | Photo Charl Devenish
Gangster book Discussion
From left: Jacques van Wyk from the Association of Certified Fraud Examiners (ACFE) Cathy Dlodlo, news editor from OFM; Pieter Roux from the UFS Business School; Alta Vermeulen from the UFS Department of Political Studies and Governance and Pieter-Louis Myburgh, author

A packed Odeion Auditorium at the University of the Free State was welcomed by Professor Helena van Zyl, Head of the UFS Business School. The reason being, a panel discussion with award-winning investigative reporter and author, Pieter-Louis Myburgh, on his much-publicised book Gangster State: Unravelling Ace Magashule's Web of Capture. The programme took the form of a panel discussion. The panellists included Pieter-Louis Myburgh, author; Jacques van Wyk from the Association of Certified Fraud Examiners (ACFE); Cathy Dlodlo, news editor from OFM; Alta Vermeulen from the UFS Department of Political Studies and Governance; and Pieter Roux from the UFS Business School.

In his introduction, Myburgh said he was happy that he was able to come to Bloemfontein and have the discussion, since South Africans should cherish freedom of speech and a free press.

The research for the book took 13 months to conclude, and during this time he spent a lot of time in the Free State and Bloemfontein. He mentioned that the book gave him the opportunity to present a condensed account of what he discovered; he could therefore share more, as opposed to just reporting on a story in the newspaper. For him, investigative reporting should always be fact based and open to scrutiny.

Some of the topics raised by the panel was concern about the perception that investigative journalists are focusing more on corruption in the public sector and less on the private sector. This was, however, discarded as a myth, as Myburgh pointed out that he exposed both private and public sector dealings in order to provide the full scope of involved parties.

Focusing on whistle blowers, the panel challenged the verification of whistle-blower information. Myburgh responded that journalists never use only one whistle-blower’s evidence, since that is merely the start of the investigation. Further investigation was necessary, and facts had to be verified. With that said, there is still a lot to be done with regard to the protection of whistle-blowers, he concluded.

The floor was opened to the audience, which provided the opportunity to ask questions and raise concerns about what was mentioned during the panel discussion. The audience eagerly participated in the discussion. In conclusion, Myburgh reiterated that society plays a vital role in keeping those in power to the promises they make.

After the discussion, the audience had the opportunity to have their books signed by the author.

News Archive

Nuclear Medicine on the forefront of cancer research
2017-07-10

Description: Nuclear Medicine on the forefront of cancer research Tags: Nuclear Medicine, cancer research, Dr Je’nine Horn-Lodewyk’s, tumour detection method, cancer, Department of Nuclear Medicine 

Dr Je’nine Horn-Lodewyk’s tumour detection method
could be the cost-effective breakthrough needed to decrease
the mortality rate in breast cancer patients.
Photo: Anja Aucamp

The field of Nuclear Medicine in South Africa and the rest of the world are expanding rapidly due to the development of hybrid cameras and new radiopharmaceuticals. These developments have a huge impact on the diagnosis and therapy of cancer.

The most advanced of these cameras, Positron emission tomography combined with normal CTs (PETCT), are not yet widely available in South Africa due to the cost of the cameras and the radiopharmaceuticals. A more cost-effective alternative can be of great benefit. To achieve this, the focus should be on developing new radiopharmaceuticals that can be used with the current cost-effective gamma cameras, according to University of the Free State researcher, Dr Je’nine Horn-Lodewyk from the Department of Nuclear Medicine.

Fluorodeoxyglucose (18F-FDG), a radiolabelled glucose analogue, is currently the radiopharmaceutical most commonly used in PET/CT imaging for mainly oncology indications. Although it is considered the gold standard for imaging in several malignancies, it does have certain disadvantages. An 18F-FDG PET/CT diagnostic imaging study can cost between R25 000 and R35 000 for a single patient in the private sector. The 18F-FDG is also more radioactive, which requires much stricter handling and shielding to avoid high radiation dosages to staff and patients.

Successful research potential innovative solution
In the search for the ideal radiopharmaceutical for tumour detection, the South African National Nuclear Energy Corporation (Necsa) developed a local synthesis process for ethylenedicysteine-deoxyglucose (EC-DG). EC-DG is also a glucose analogue similar to FDG. They succeeded in labelling the compound with Technetium-99-metastable-pertechnetate (99mTcO4-), the most common nuclear medicine isotope used for approximately 95% of nuclear medicine procedures, creating 99mTc-EC-DG.

In partnership with Dr Horn-Lodewyk, this compound was successfully used in various animal models and clinical scenarios, resulting in approval by the Medicine Control Council to use it in a human study. Research is also planned in order to investigate diagnostic accuracy in other cancers like lymphoma.  The end result of this research can produce a radiopharmaceutical that is cost effective, does not require the use of costly specialised equipment, has no significant side-effects, no special patient preparation, renders late imaging possible, and has decreased radiation risks.

Dr Horn-Lodewyk is grateful for the support of her mentor, Prof Anton Otto, as well as Dr Gert Engelbrecht, Head of the Department of Nuclear Medicine, Prof Jan Rijn Zeevaart from North-West University’s Preclinical Drug Development Platform and Necsa, and Judith Wagener from Necsa. This innovative research would also not have been possible without the financial assistance of Dr Glen Taylor and Eleanor van der Westhuizen in the Directorate of Research Development.

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