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28 May 2019 Photo Charl Devenish
UFS Africa celebration
I am not African because I was born in Africa, but because Africa was born in me,” Kwame Nkrumah, Ghana’s first president, and a founding father of the African Union.

Since the African Union’s establishment in 1963, the continent marks Africa Day on 25 May annually. To commemorate the achievements made by African leaders 56 years ago to decolonise the continent and pave the way for a united front on the global stage, the University of the Free State (UFS) hosts various events.

Ubuntu our beginning, ubuntu our ending 

The university celebrated Africa Day a day early this year. The Office for International Affairs coordinated the 2019 Africa Day Reflection and Celebration on 24 May 2019 at the Bloemfontein Campus. A dialogue session delved into the question of what ubuntu has evolved to mean in modern-day society and how best it can be embodied.

Moderator of the dialogue, Ace Moloi, reckoned that “we have a right not only to give ubuntu but to demand and invoke it from other people.” Staff, students and panellists engaged on the aphorism umuntu ngumuntu ngabantu and whether the philosophical principle is a pragmatic way of doing things or is only referred to when self-correcting.

Prof Colin Chasi, from the UFS Department of Communication Science, touched on how ubuntu is embedded in many Nguni languages. A case in point being the implied presence and connectivity typical found in indigenous language greetings. Other panellists including Prof Karin van Marle( Public Law lecturer at the UFS), Thapelo Mokoatsi,History lecturer at the UFS and Matau Setshase, UFS researcher, made contributions on decolonisation, individual identity, reconciliation, social issues, and traditional healers. The consensus reached was that a lot work still needs to be done in understanding and living the values represented by ubuntu.

Qwaqwa Campus Celebration

The Office for International Affairs (OIA) also hosted the first Annual Africa Day Student Dialogue on the Qwaqwa Campus under the theme: Health, Wellbeing, Access, Social inclusion, Equity and Equality on the African continent.

Africa Day Memorial Lecture

Presenting the 2019 Africa Day Memorial Lecture, Prof Francis Nyamnjoh, from University of Cape Town, delved into the topic of Ubuntuism and Africa: Actualised, Misappropriated, Endangered and Reappraised. “I seek to give currency to concepts such African communitarianism, ubuntu, Africanness, Afrocentricity, Afrocentrism, Africanity, Afrikology, humanness, wholeness and reciprocal altruism,” he said.

Hosted by the Centre for Gender and Africa Studies on 22 May 2019 the annual lecture is a calendar constant which reflects on the importance of celebrating the continent and its people.
 
Migration debate unpacked borders 

The UFS Debate Society reflected on borders and migration in Southern Africa on 21 May 2019. The debate unpacked the topic: The Southern African Development Community should develop a free internal migration policy. 

Lecturers also delivered presentations that dissected African societies, the nine frontier wars between the British and amaXhosa that formed South Africa’s borders, and the influence of labour and capital on migration. In closing, African international students shared their lived experiences, hardships and triumphs within the continent.

News Archive

UFS study on cell development in top international science journal
2008-09-16

A study from the University of the Free State (UFS) on how the change in the packaging of DNA with cell development influenced the expression of genes, will be published in this week’s early edition of the prestigious international, peer-reviewed science journal, the Proceeding of the National Academy of Sciences of the USA (PNAS).

The PNAS journal has an impact factor of 10, which means that studies published in the journal are, on average, referred to by ten other scientific studies in a two year period. The South African Journal of Science, by comparison, has an impact factor of 0.7.

The UFS study, funded by the Wellcome Trust and the National Research Foundation (NRF), looked at how the change in the packaging of DNA with cell development influenced the expression of genes. It is very relevant to research on stem cells, an area of medicine that studies the possible use of undifferentiated cells to replace damaged tissue.

Prof. Hugh Patterton, of the Department of Microbial, Biochemical and Food Biotechnology at the UFS, who led the study, said: "We are extremely proud of this study. It was conceived in South Africa, it was performed in South Africa, the data were analysed in South Africa, and it was published from South Africa."

When a gene is expressed, the information encoded in the gene is used to manufacture a specific protein. In eukaryotes, which include humans, there is approximately 1m of DNA, containing the genes, in every cell. This length of DNA has to fit into a cell nucleus with a diameter of only about 10 micrometer. In order to fit the DNA into such a small volume, eukaryotic cells wrap their DNA onto successive protein balls, termed nucleosomes. Strings of nucleosomes, resembling a bead of pearls, is folded into a helix to form a chromatin fiber. The study from the UFS investigated how the binding of a specific protein, termed a linker histone, that binds to the length of DNA between nucleosomes, influenced the formation of the chromatin fiber and also the activity of genes.

"We found that the linker histone bound to chromatin in yeast, which we use as a model eukaryote, under conditions where virtually all the genes in the organism were inactive. It was widely believed that the binding of the linker histone caused the inactivation of genes. We studied the relationship between the amount of linker histone bound in the vicinity of each gene and the expression of that gene for all the genes in yeast, using genomic techniques. We made the surprising discovery that even through the linker histone preferentially bound to genes under conditions where the genes were shut off, this inactivation of genes was not caused by the binding of the linker histone and folding of the chromatin,” said Prof. Patterton.

He said: “Instead our data strongly suggested that the observed anti-correlation was due to the movement of enzymes along the DNA molecule, involved in processing the information in genes for the eventual manufacture of proteins. This movement of enzymes displaced the linker histones from the DNA. This finding now requires a rethink on aspects of how packaging of DNA influences gene activity."

Prof. Patterton said that his research group, using the Facility for Genomics and Proteomics as well as the Bioinformatics Node at the UFS, was currently busy with follow-up studies to understand how other proteins in nucleosomes affected the activities of genes, as well as with projects to understand how chemicals found in red wine and in green tea extended lifespan. "We are certainly having a marvelous time trying to understand the fundamental mechanisms of life, and the UFS is an exciting place to be if one was interested in studying life at the level of molecules," he said.


Media Release
Issued by: Lacea Loader
Assistant Director: Media Liaison
Tel: 051 401 2584
Cell: 083 645 2454
E-mail: loaderl.stg@ufs.ac.za  
18 September 2008
 

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