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28 October 2019 | Story Leonie Bolleurs | Photo Anja Aucamp
Dr Brain van Soelen and Prof Pieter Meintjies
UFS scientists, Prof Pieter Meintjes and Dr Brian van Soelen, are part of the prestigious H.E.S.S. collaboration that recently published in Nature Astronomy.

Think of an object with a mass exceeding that of the Sun, squeezed into a volume of a sphere with the radius of a city like Bloemfontein. This very dense, compact object, known as a pulsar, is also a great source of energy. According to Physics Professor, Prof Pieter Meintjes, this pulsar (neutron star produced in supernova explosion) is also a key element of a recently submitted paper in Nature Astronomy.

Prof Meintjes and Dr Brian van Soelen, Senior Lecturer, both from the Department of Physics at the University of the Free State (UFS), were part of the High Energy Stereoscopic System (H.E.S.S.) collaboration of 220-plus scientists worldwide who worked on the paper Resolving the Crab pulsar wind nebula at tera-electronvolt energies, published in the prestige journal Nature Astronomy. 

According to Prof Meintjes, the fact that the paper was accepted for publication in Nature Astronomy testifies of the importance of this finding in the high-energy astrophysics community.

Powerful generators of electricity

He elaborates on the study: “The name pulsar originates from the fact that rotating neutron stars produced in supernova explosions produce beams of radiation, much like a lighthouse. Every time the beam intersects the observer’s line of sight, the observer receives a pulse of radiation.”

“As a result of this enormous mass squeezed into a small volume, these objects have the same density as that of an atomic nucleus. These objects (very dense pulsars) spin very rapidly and have enormous magnetic fields; for example, the pulsar at the centre of the Crab Nebulae spins around its axis once every 33 milliseconds (millisecond: one thousandth of a second) and possesses a magnetic field strength of the order of one tera-Gauss (tera – million x million). For comparison, the average strength of the Earth’s magnetic field is 0.5. Gauss and the magnetic field strength on the Sun ranges between 1 000 and 4 000 Gauss.”

“Because of this very super-strong rapid-spinning magnet, enormous electric fields are induced that can accelerate particles such as electrons and protons to energies in excess of one tera-electronvolt (optical light that are emitted by an ordinary lightbulb has energies of the order of one electronvolt).”

Prof Meintjes continues: “This means that these fast-rotating neutron stars are extraordinary powerful generators of electricity, which fills the surrounding cloud (supernova remnant) with super-high energy-charged particles that can produce, in turn, very high energy gamma rays through various processes such as synchrotron radiation and inverse-Compton radiation, to name a few.”

H.E.S.S. collaboration 

Above one tera-electronvolt, the gamma rays are detected by huge ground-based telescopes such as H.E.S.S., utilising the Earth’s atmosphere.

“When these high-energy gamma rays enter the atmosphere, they produce showers of super-relativistic particles that produce Cherenkov light – detected by the telescope. The technique is called the Atmospheric Cherenkov Technique (ACT).”

HESS
The High Energy Stereoscopic System. (Photo: Supplied)

“The H.E.S.S. gamma-ray collaboration is but one collaboration that has studied this source intensively over the past couple of decades or so.  Being the most powerful gamma-ray telescope facility currently operational, very careful analysis of the data managed to reveal that the gamma-ray emitting region inside the nebula is about 10 times bigger in size than the region where the x-rays are emitted within the nebula.” 

“This has solved a long-standing question as to how big the gamma-ray emitting region within these supernova remnants are, compared to the region where the x-rays, for example, originates,” says Prof Meintjes. 

Both Prof Meintjes and Dr Van Soelen are members of this prestigious H.E.S.S. collaboration. Their participation in this project, together with scientists from universities such as the University of Oxford, the University of Leicester, and the University of Bordeaux, opens up valuable research opportunities for UFS postgraduate students to enter the international stage and interact with the best scientists in the world.

They are also members of the editorial board responsible for the internal review of research papers before being submitted to more prestigious journals, for example, Nature Astronomy. Dr Van Soelen is also a coordinator of multi-wavelength follow-up observations within the H.E.S.S. collaboration. 

This is the second time that Prof Meintjes published in Nature Astronomy. Previously, he was co-author of a paper on emission from a white dwarf pulsar, showing that fast-rotating white dwarf stars could in fact mimic emission from neutron star pulsars. He developed the theoretical model reported in that paper, explaining the multi-wavelength emission from radio to X-ray energies.


News Archive

#Women'sMonth: Save the children
2017-08-10

Description: Trudi O'Neill Tags: : rotaviruses, young children, Dr Trudi O’Neill, Department of Microbial, Biochemical and Food Biotechnology, vaccine 

Dr Trudi O’Neill, Senior lecturer in the Department of
Microbial, Biochemical and Food Biotechnology.
Photo: Anja Aucamp

Dr Trudi O’Neill, Senior lecturer in the Department of Microbial, Biochemical and Food Biotechnology, is conducting research on rotavirus vaccines.

Dr O’Neill was inspired to conduct research on this issue through her fascination with the virus. “The biology of rotaviruses, especially the genome structure and the virus’ interaction with the host, is fascinating.”

“In fact, it is estimated that, globally, ALL children will be infected with rotavirus before the age of five, irrespective of their socio-economic standing. However, infants and young children in poor countries are more vulnerable due to inadequate healthcare. The WHO estimates that approximately 215 000 deaths occur each year. This roughly equates to eight Airbus A380 planes, the largest commercial carrier with a capacity of approximately 500 seats, filled with only children under the age of five, crashing each week of every year.”

Alternative to expensive medicines 
“Currently, there are two vaccines that have been licensed for global use. However, these vaccines are expensive and poor countries, where the need is the greatest, are struggling to introduce them sustainably. It is therefore appealing to study rotaviruses, as it is scientifically challenging, but could at the same time have an impact on child health,” Dr O’Neill said.

The main focus of Dr O’Neill’s research is to develop a more affordable vaccine that can promote child vaccination in countries/areas that cannot afford the current vaccines.

All about a different approach 

When asked about the most profound finding of her research, Dr O’Neill responded: “It is not so much a finding, but rather the approach. My rotavirus research group is making use of yeast as vehicle to produce a sub-unit vaccine. These microbes are attractive, as they are relatively easy to manipulate and cheap to cultivate. Downstream production costs can therefore be reduced. The system we use was developed by my colleagues, Profs Koos Albertyn and Martie Smit, and allows for the potential use of any yeast. This enables us to screen a vast number of yeasts in order to identify the best yeast producer.”

Vaccination recently acquired a bad name in the media for its adverse side effects. As researcher, Dr O’Neill has this to say: “Vaccines save lives. By vaccinating your child, you don’t just protect your own child from a potentially deadly infection, but also other children in your community that might be too young to be vaccinated or have pre-existing health problems that prevents vaccination.” 

A future without rotavirus vaccination?

Dr O’Neill believes a future without rotavirus vaccination will be a major step backwards, as the impact of rotavirus vaccines has been profound. “Studies in Mexico and Malawi actually show a reduction in deaths. A colleague in Mozambique has commented on the empty hospital beds that amazed both clinicians and scientists only one year after the introduction of the vaccine in that country. Although many parents, mostly in developed countries, don’t have to fear dehydrating diarrhoea and potential hospitalisation of their babies due to rotavirus infection anymore, such an infection could still be a death sentence in countries that have not been able to introduce the vaccine in their national vaccination programmes,” she said. 

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