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28 October 2019 | Story Leonie Bolleurs | Photo Anja Aucamp
Dr Brain van Soelen and Prof Pieter Meintjies
UFS scientists, Prof Pieter Meintjes and Dr Brian van Soelen, are part of the prestigious H.E.S.S. collaboration that recently published in Nature Astronomy.

Think of an object with a mass exceeding that of the Sun, squeezed into a volume of a sphere with the radius of a city like Bloemfontein. This very dense, compact object, known as a pulsar, is also a great source of energy. According to Physics Professor, Prof Pieter Meintjes, this pulsar (neutron star produced in supernova explosion) is also a key element of a recently submitted paper in Nature Astronomy.

Prof Meintjes and Dr Brian van Soelen, Senior Lecturer, both from the Department of Physics at the University of the Free State (UFS), were part of the High Energy Stereoscopic System (H.E.S.S.) collaboration of 220-plus scientists worldwide who worked on the paper Resolving the Crab pulsar wind nebula at tera-electronvolt energies, published in the prestige journal Nature Astronomy. 

According to Prof Meintjes, the fact that the paper was accepted for publication in Nature Astronomy testifies of the importance of this finding in the high-energy astrophysics community.

Powerful generators of electricity

He elaborates on the study: “The name pulsar originates from the fact that rotating neutron stars produced in supernova explosions produce beams of radiation, much like a lighthouse. Every time the beam intersects the observer’s line of sight, the observer receives a pulse of radiation.”

“As a result of this enormous mass squeezed into a small volume, these objects have the same density as that of an atomic nucleus. These objects (very dense pulsars) spin very rapidly and have enormous magnetic fields; for example, the pulsar at the centre of the Crab Nebulae spins around its axis once every 33 milliseconds (millisecond: one thousandth of a second) and possesses a magnetic field strength of the order of one tera-Gauss (tera – million x million). For comparison, the average strength of the Earth’s magnetic field is 0.5. Gauss and the magnetic field strength on the Sun ranges between 1 000 and 4 000 Gauss.”

“Because of this very super-strong rapid-spinning magnet, enormous electric fields are induced that can accelerate particles such as electrons and protons to energies in excess of one tera-electronvolt (optical light that are emitted by an ordinary lightbulb has energies of the order of one electronvolt).”

Prof Meintjes continues: “This means that these fast-rotating neutron stars are extraordinary powerful generators of electricity, which fills the surrounding cloud (supernova remnant) with super-high energy-charged particles that can produce, in turn, very high energy gamma rays through various processes such as synchrotron radiation and inverse-Compton radiation, to name a few.”

H.E.S.S. collaboration 

Above one tera-electronvolt, the gamma rays are detected by huge ground-based telescopes such as H.E.S.S., utilising the Earth’s atmosphere.

“When these high-energy gamma rays enter the atmosphere, they produce showers of super-relativistic particles that produce Cherenkov light – detected by the telescope. The technique is called the Atmospheric Cherenkov Technique (ACT).”

HESS
The High Energy Stereoscopic System. (Photo: Supplied)

“The H.E.S.S. gamma-ray collaboration is but one collaboration that has studied this source intensively over the past couple of decades or so.  Being the most powerful gamma-ray telescope facility currently operational, very careful analysis of the data managed to reveal that the gamma-ray emitting region inside the nebula is about 10 times bigger in size than the region where the x-rays are emitted within the nebula.” 

“This has solved a long-standing question as to how big the gamma-ray emitting region within these supernova remnants are, compared to the region where the x-rays, for example, originates,” says Prof Meintjes. 

Both Prof Meintjes and Dr Van Soelen are members of this prestigious H.E.S.S. collaboration. Their participation in this project, together with scientists from universities such as the University of Oxford, the University of Leicester, and the University of Bordeaux, opens up valuable research opportunities for UFS postgraduate students to enter the international stage and interact with the best scientists in the world.

They are also members of the editorial board responsible for the internal review of research papers before being submitted to more prestigious journals, for example, Nature Astronomy. Dr Van Soelen is also a coordinator of multi-wavelength follow-up observations within the H.E.S.S. collaboration. 

This is the second time that Prof Meintjes published in Nature Astronomy. Previously, he was co-author of a paper on emission from a white dwarf pulsar, showing that fast-rotating white dwarf stars could in fact mimic emission from neutron star pulsars. He developed the theoretical model reported in that paper, explaining the multi-wavelength emission from radio to X-ray energies.


News Archive

UFS study on cell development in top international science journal
2008-09-16

A study from the University of the Free State (UFS) on how the change in the packaging of DNA with cell development influenced the expression of genes, will be published in this week’s early edition of the prestigious international, peer-reviewed science journal, the Proceeding of the National Academy of Sciences of the USA (PNAS).

The PNAS journal has an impact factor of 10, which means that studies published in the journal are, on average, referred to by ten other scientific studies in a two year period. The South African Journal of Science, by comparison, has an impact factor of 0.7.

The UFS study, funded by the Wellcome Trust and the National Research Foundation (NRF), looked at how the change in the packaging of DNA with cell development influenced the expression of genes. It is very relevant to research on stem cells, an area of medicine that studies the possible use of undifferentiated cells to replace damaged tissue.

Prof. Hugh Patterton, of the Department of Microbial, Biochemical and Food Biotechnology at the UFS, who led the study, said: "We are extremely proud of this study. It was conceived in South Africa, it was performed in South Africa, the data were analysed in South Africa, and it was published from South Africa."

When a gene is expressed, the information encoded in the gene is used to manufacture a specific protein. In eukaryotes, which include humans, there is approximately 1m of DNA, containing the genes, in every cell. This length of DNA has to fit into a cell nucleus with a diameter of only about 10 micrometer. In order to fit the DNA into such a small volume, eukaryotic cells wrap their DNA onto successive protein balls, termed nucleosomes. Strings of nucleosomes, resembling a bead of pearls, is folded into a helix to form a chromatin fiber. The study from the UFS investigated how the binding of a specific protein, termed a linker histone, that binds to the length of DNA between nucleosomes, influenced the formation of the chromatin fiber and also the activity of genes.

"We found that the linker histone bound to chromatin in yeast, which we use as a model eukaryote, under conditions where virtually all the genes in the organism were inactive. It was widely believed that the binding of the linker histone caused the inactivation of genes. We studied the relationship between the amount of linker histone bound in the vicinity of each gene and the expression of that gene for all the genes in yeast, using genomic techniques. We made the surprising discovery that even through the linker histone preferentially bound to genes under conditions where the genes were shut off, this inactivation of genes was not caused by the binding of the linker histone and folding of the chromatin,” said Prof. Patterton.

He said: “Instead our data strongly suggested that the observed anti-correlation was due to the movement of enzymes along the DNA molecule, involved in processing the information in genes for the eventual manufacture of proteins. This movement of enzymes displaced the linker histones from the DNA. This finding now requires a rethink on aspects of how packaging of DNA influences gene activity."

Prof. Patterton said that his research group, using the Facility for Genomics and Proteomics as well as the Bioinformatics Node at the UFS, was currently busy with follow-up studies to understand how other proteins in nucleosomes affected the activities of genes, as well as with projects to understand how chemicals found in red wine and in green tea extended lifespan. "We are certainly having a marvelous time trying to understand the fundamental mechanisms of life, and the UFS is an exciting place to be if one was interested in studying life at the level of molecules," he said.


Media Release
Issued by: Lacea Loader
Assistant Director: Media Liaison
Tel: 051 401 2584
Cell: 083 645 2454
E-mail: loaderl.stg@ufs.ac.za  
18 September 2008
 

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