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23 October 2019 | Story Rulanzen Martin | Photo Rulanzen Martin
Prof Angelique van Niekerk, Prof Jaap Steyn, Prof Hennie van Coller and Prof Bernard Odendaal
From the left: Prof Angelique van Niekerk, Prof Jaap Steyn, Prof Hennie van Coller, research fellow and former HOD of Afrikaans and Dutch; German and French and Prof Bernard Odendaal, from the ATKV School for Creative Writing at North West University,after the book launch on 16 October 2019.

The very comprehensive publication, JC Steyn en Afrikaans – ’n viering, pays tribute to a leading figure of the Afrikaans academic world. The book, edited by Profs Angelique van Niekerk, Hennie van Coller, and Bernard Odendaal, was recently launched at the University of the Free State (UFS) as a tribute to Prof Jaap Steyn, research fellow and former colleague at the UFS.

“The publication contains diverse contributions and provides a comprehensive overview of the different types of research in Afrikaans literature and linguistics,” said Prof van Niekerk, Head of the Department of Afrikaans and Dutch, German and French at the UFS. 

The scope of the contributions is as wide as the influence Prof Steyn has had on the Afrikaans language landscape. “Creative writing and biographies lexicography and sociolinguistics are addressed in his book,” Prof van Niekerk said.

As mentioned in the title, the publication serves as a celebration of Afrikaans as a language and discipline; it also covers the research areas in which Prof Steyn used to publish research himself.

The book, published by SUN MeDIA, was made possible by a financial donation from the South African Academy for Science and Art. It was officially launched at the UFS on Wednesday 16 October 2019. 

More about Prof Steyn 

Prof Steyn is a seasoned poet, writer, and one of the leading Afrikaans academics in the country. With more than 100 articles in scientific journals to his name, Prof Steyn is still serving as research fellow in the UFS Department of Afrikaans and Dutch, German and French. He is also the author of, among others, books on language politics, language, and cultural history, such as Tuiste in eie taal, Trouwe Afrikaners: Aspekte van Afrikanernasionalisme en Suid-Afrikaanse taalpolitiek and the recent Ons gaan ’n taal maak. He has also written a number of award-winning biographies and published prose and poetry. 

Prof Steyn has been associated with several South African universities, including the University of Johannesburg (the then Rand Afrikaans Universiteit), Nelson Mandela University (the then University of Port Elizabeth), as well as the UFS.

News Archive

Nuclear Medicine on the forefront of cancer research
2017-07-10

Description: Nuclear Medicine on the forefront of cancer research Tags: Nuclear Medicine, cancer research, Dr Je’nine Horn-Lodewyk’s, tumour detection method, cancer, Department of Nuclear Medicine 

Dr Je’nine Horn-Lodewyk’s tumour detection method
could be the cost-effective breakthrough needed to decrease
the mortality rate in breast cancer patients.
Photo: Anja Aucamp

The field of Nuclear Medicine in South Africa and the rest of the world are expanding rapidly due to the development of hybrid cameras and new radiopharmaceuticals. These developments have a huge impact on the diagnosis and therapy of cancer.

The most advanced of these cameras, Positron emission tomography combined with normal CTs (PETCT), are not yet widely available in South Africa due to the cost of the cameras and the radiopharmaceuticals. A more cost-effective alternative can be of great benefit. To achieve this, the focus should be on developing new radiopharmaceuticals that can be used with the current cost-effective gamma cameras, according to University of the Free State researcher, Dr Je’nine Horn-Lodewyk from the Department of Nuclear Medicine.

Fluorodeoxyglucose (18F-FDG), a radiolabelled glucose analogue, is currently the radiopharmaceutical most commonly used in PET/CT imaging for mainly oncology indications. Although it is considered the gold standard for imaging in several malignancies, it does have certain disadvantages. An 18F-FDG PET/CT diagnostic imaging study can cost between R25 000 and R35 000 for a single patient in the private sector. The 18F-FDG is also more radioactive, which requires much stricter handling and shielding to avoid high radiation dosages to staff and patients.

Successful research potential innovative solution
In the search for the ideal radiopharmaceutical for tumour detection, the South African National Nuclear Energy Corporation (Necsa) developed a local synthesis process for ethylenedicysteine-deoxyglucose (EC-DG). EC-DG is also a glucose analogue similar to FDG. They succeeded in labelling the compound with Technetium-99-metastable-pertechnetate (99mTcO4-), the most common nuclear medicine isotope used for approximately 95% of nuclear medicine procedures, creating 99mTc-EC-DG.

In partnership with Dr Horn-Lodewyk, this compound was successfully used in various animal models and clinical scenarios, resulting in approval by the Medicine Control Council to use it in a human study. Research is also planned in order to investigate diagnostic accuracy in other cancers like lymphoma.  The end result of this research can produce a radiopharmaceutical that is cost effective, does not require the use of costly specialised equipment, has no significant side-effects, no special patient preparation, renders late imaging possible, and has decreased radiation risks.

Dr Horn-Lodewyk is grateful for the support of her mentor, Prof Anton Otto, as well as Dr Gert Engelbrecht, Head of the Department of Nuclear Medicine, Prof Jan Rijn Zeevaart from North-West University’s Preclinical Drug Development Platform and Necsa, and Judith Wagener from Necsa. This innovative research would also not have been possible without the financial assistance of Dr Glen Taylor and Eleanor van der Westhuizen in the Directorate of Research Development.

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