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18 October 2019 | Story Thabo Kessah | Photo Tshepo Moeketsi
Prof Pearl Sithole
Prof Pearl Sithole says higher education needs to create space for Africa to be contributors and innovators of knowledge.

“Excellence is my main priority. For me, excellence means mastery of cross-communicable science and liberation of intellectual creativity that is free of mere complacency and acknowledging the right to analyse from where we stand. I am unapologetic about indigenous knowledge being the basis for scientific advancement.” This is how the newly appointed Vice-Principal: Academic and Research, Prof Pearl Sithole, sums up her vision and plan for academia and research on the Qwaqwa Campus. 

She believes that the human mind is geared towards ‘seeking and constantly explaining itself in the service of innovative change.’ 

“With this service of innovative change fully realised, the Qwaqwa Campus will be able to produce students who can analyse, innovate, and solve real social and world problems. For me, this is the University of the Free State graduate I pine to see – and there had better be truth to the ‘free’ part of this intellectual soul! I see Qwaqwa as a site for this intellectual innovation catalyst,” she said.

Social anthropologist

Prof Sithole is a Social Anthropology graduate with both master’s and PhD degrees from the University of Cambridge in England. “I stumbled upon Anthropology as part of my three majors at the then University of Durban-Westville. This discipline confessed its previous conceptual sins in a way that inspired change! From the exploration of human origins, to economic and political developments, and that was Anthropology. I was just absolutely taken by its acknowledgement of the intellectual project being socio-culturally rooted,” she said about her chosen area of study.

“I have always been inspired by Archie Mafeje’s work. I was motivated by Bernard Magubane’s scholarship, and I marvelled at the rigour of Oyeronke Oyewumi and Marilyn Strathern in feminist discourse. I mention these, because they inspire intellectual passion in me and I eventually met them,” she added.

Higher education in SA

She believes the higher-education sector is succumbing to streamlining methods, uninformed processes, and very little impact. “Like in government, higher education should not suffer from reduction of people into statistics, interventions into annual performance plan targets, and planning and monitoring into sanitised expenditure against targets. I see the shortage of relevance, responsiveness, and humanness; as well as ‘being captured’ by the latest fashions of doing rigid academe as the major challenges of higher education in South Africa today. We need to liberate our own innovative potential. We really need to create space for Africa to be contributors and innovators of knowledge,” Prof Sithole, the author of Unequal Peers, said.

She is, however, optimistic about the future of higher education in South Africa. “The day that we will have our innovation systems and systems of defining excellence – liberated from merely kneeling before the altar of Westernisation – we will gain integrity both conceptually and instrumentally in terms of responding to a society that is waiting for higher education to solve societal problems. The solution is to let those who see this truth continue to produce the knowledge despite being less than pleasing to the average scientific oversight bodies steeped in conventional Western validation.”

Research interests

Prof Sithole was previously employed with the Public Service Commission as a commissioner, a position she held from 2015 to August 2019. Prior to that, she worked at the University of KwaZulu-Natal as an Associate Professor of Community Development from 2010 to 2015, and at the South African Human Sciences Research Council (HSRC) as a senior researcher from 2006 to 2010. Her research interests and areas of expertise are governance, gender and development, analysis of social inequality, and the politics of knowledge production.


News Archive

Link between champagne bubbles and the UFS?
2012-11-16

Prof. Lodewyk Kock with an example of a front page of the publication FEMS Yeast Research, as adapted by F. Belliard, FEMS Central Office.
Photo: Leatitia Pienaar
15 November 2012

What is the link between the bubbles in champagne and breakthrough research being done at the Mayo Clinic in America? Nano research being done at our university.

Prof. Lodewyk Kock of Biotechnology says a human being consists of millions of minute cells that are invisible to the eye. The nano technology team at the UFS have developed a technique that allows researchers to look into such a cell, as well as other microorganisms. In this way, they can get an idea of what the cell’s “insides” look like.

The UFS team – consisting of Profs. Kock, Hendrik Swart (Physics), Pieter van Wyk (Centre for Microscopy), as well as Dr Chantel Swart (Biotechnology), Dr Carlien Pohl (Biotechnology) and Liza Coetsee (Physics) – were amazed to see that the inside of cells consist of a maze of small tunnels or blisters. Each tunnel is about 100 and more nanometres in diameter – about one ten thousandth of a millimetre – that weaves through the cells in a maze.

It was also found that these tunnels are the “lungs” of the cells. Academics doing research on yeast have had to sit up and take notice of the research being done at the UFS – to the extent that these “lungs” will appear on the front page of the highly acclaimed FEMS Yeast Research for all of 2013.

The Mayo Clinic, in particular, now wants to work with the UFS to study cancer cells in more detail in order to fight this disease, says Prof. Kock. The National Cancer Institute of America has also shown interest. This new nano technology for biology can assist in the study and development of nano medicine that can be used in the treatment of cancer and other life threatening diseases. Nano medicine uses nano metal participles that are up to one billionth of a metre in size.

Prof. Kock says laboratory tests indicate that nano medicine can improve the efficacy of anti-cancer medicine, which makes the treatment less toxic. “According to the Mayo Clinic team, nano particles are considered as a gold cartridge which is being fired directly at a cancer tumour. This is compared to fine shot that spreads through the body and also attacks healthy cells.”

“This accuracy implies that the chemotherapy dose can be lowered with fewer side effects. The Mayo Clinic found that one-tenth of the normal dosage is more effective against pancreas cancer in this way than the full dosage with a linkage to nano particles. According to the clinic, this nano medicine could also delay the spread of cancer,” says Prof. Kock.

The nano particles are used as messengers that convey anti-cancer treatment to cancer cells, where it then selectively kills the cancer cells. The transport and transfer of these medicines with regard to gold nano particles can be traced with the UFS’s nano technology to collect more information, especially where it works on the cell.

“With the new nano technology of the UFS, it is possible to do nano surgery on the cells by slicing the cells in nanometre thin slices while the working of the nano medicine is studied. In this way, it can be established if the nano medicine penetrates the cells or if it is only associated with the tiny tunnels,” says Prof. Kock.

And in champagne the small “lungs” are responsible for the bubbles. The same applies to beer and with this discovery a whole new reach field opens for scientists.

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