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18 October 2019 | Story Thabo Kessah | Photo Tshepo Moeketsi
Prof Pearl Sithole
Prof Pearl Sithole says higher education needs to create space for Africa to be contributors and innovators of knowledge.

“Excellence is my main priority. For me, excellence means mastery of cross-communicable science and liberation of intellectual creativity that is free of mere complacency and acknowledging the right to analyse from where we stand. I am unapologetic about indigenous knowledge being the basis for scientific advancement.” This is how the newly appointed Vice-Principal: Academic and Research, Prof Pearl Sithole, sums up her vision and plan for academia and research on the Qwaqwa Campus. 

She believes that the human mind is geared towards ‘seeking and constantly explaining itself in the service of innovative change.’ 

“With this service of innovative change fully realised, the Qwaqwa Campus will be able to produce students who can analyse, innovate, and solve real social and world problems. For me, this is the University of the Free State graduate I pine to see – and there had better be truth to the ‘free’ part of this intellectual soul! I see Qwaqwa as a site for this intellectual innovation catalyst,” she said.

Social anthropologist

Prof Sithole is a Social Anthropology graduate with both master’s and PhD degrees from the University of Cambridge in England. “I stumbled upon Anthropology as part of my three majors at the then University of Durban-Westville. This discipline confessed its previous conceptual sins in a way that inspired change! From the exploration of human origins, to economic and political developments, and that was Anthropology. I was just absolutely taken by its acknowledgement of the intellectual project being socio-culturally rooted,” she said about her chosen area of study.

“I have always been inspired by Archie Mafeje’s work. I was motivated by Bernard Magubane’s scholarship, and I marvelled at the rigour of Oyeronke Oyewumi and Marilyn Strathern in feminist discourse. I mention these, because they inspire intellectual passion in me and I eventually met them,” she added.

Higher education in SA

She believes the higher-education sector is succumbing to streamlining methods, uninformed processes, and very little impact. “Like in government, higher education should not suffer from reduction of people into statistics, interventions into annual performance plan targets, and planning and monitoring into sanitised expenditure against targets. I see the shortage of relevance, responsiveness, and humanness; as well as ‘being captured’ by the latest fashions of doing rigid academe as the major challenges of higher education in South Africa today. We need to liberate our own innovative potential. We really need to create space for Africa to be contributors and innovators of knowledge,” Prof Sithole, the author of Unequal Peers, said.

She is, however, optimistic about the future of higher education in South Africa. “The day that we will have our innovation systems and systems of defining excellence – liberated from merely kneeling before the altar of Westernisation – we will gain integrity both conceptually and instrumentally in terms of responding to a society that is waiting for higher education to solve societal problems. The solution is to let those who see this truth continue to produce the knowledge despite being less than pleasing to the average scientific oversight bodies steeped in conventional Western validation.”

Research interests

Prof Sithole was previously employed with the Public Service Commission as a commissioner, a position she held from 2015 to August 2019. Prior to that, she worked at the University of KwaZulu-Natal as an Associate Professor of Community Development from 2010 to 2015, and at the South African Human Sciences Research Council (HSRC) as a senior researcher from 2006 to 2010. Her research interests and areas of expertise are governance, gender and development, analysis of social inequality, and the politics of knowledge production.


News Archive

Research eradicates bacteria from avocado facility
2017-01-17

 Description: Listeria monocytogenes Tags: Listeria monocytogenes

Listeria monocytogenes as seen under an electron
microscope. The photo was taken with a transmission
electron microscope at the microscopy unit of the UFS.
Bacteriophages (lollipop-like structures) can be seen
next to the bacterial cells.
Photo: Supplied

“The aim of my project was to identify and characterise the contamination problem in an avocado-processing facility and then to find a solution,” said Dr Amy Strydom, postdoctoral fellow in the Department of Microbial Biochemical and Food Biotechnology at the University of the Free State (UFS).

Her PhD, “Control of Listeria monocytogenes in an Avocado-processing Facility”, aimed to identify and characterise the contamination problem in a facility where avocados were processed into guacamole. Dr Strydom completed her MSc in food science in 2009 at Stellenbosch University and this was the catalyst for her starting her PhD in microbiology in 2012 at the UFS. The research was conducted over a period of four years and she graduated in 2016. The research project was funded by the National Research Foundation.

The opportunity to work closely with the food industry further motivated Dr Strydom to conduct her research. The research has made a significant contribution to a food producer (avocado facility) that will sell products that are not contaminated with any pathogens. The public will then buy food that is safe for human consumption.


What is Listeria monocytogenes?

Listeria monocytogenes is a food-borne pathogenic bacterium. When a food product is contaminated with L. monocytogenes, it will not be altered in ways that are obvious to the consumer, such as taste and smell. When ingested, however, it can cause a wide range of illnesses in people with impaired immune systems. “Risk groups include newborn babies, the elderly, and people suffering from diseases that weaken their immune systems,” Dr Strydom said. The processing adjustments based on her findings resulted in decreased numbers of Listeria in the facility.

The bacteria can also survive and grow at refrigeration temperatures, making them dangerous food pathogens, organisms which can cause illnesses [in humans]. Dr Strydom worked closely with the facility and developed an in-house monitoring system by means of which the facility could test their products and the processing environment. She also evaluated bacteriophages as a biological control agent in the processing facility. Bacteriophages are viruses that can only infect specific strains of bacteria. Despite bacteriophage products specifically intended for the use of controlling L. monocytogenes being commercially available in the food industry, Dr Strydom found that only 26% of the L. monocytogenes population in the facility was destroyed by the ListexP100TM product. “I concluded that the genetic diversity of the bacteria in the facility was too high and that the bacteriophages could not be used as a control measure. However, there is much we do not understand about bacteriophages, and with a few adjustments, we might be able to use them in the food industry.”

Microbiological and molecular characterisation of L. monocytogenes

The bacteria were isolated and purified using basic microbiological culturing. Characterisation was done based on specific genes present in the bacterial genome. “I amplified these genes with polymerase chain reaction (PCR), using various primers targeting these specific genes,” Dr Strydom said. Some amplification results were analysed with a subsequent restriction digestion where the genes were cut in specific areas with enzymes to create fragments. The lengths of these fragments can be used to differentiate between strains. “I also compared the whole genomes of some of the bacterial strains.” The bacteriophages were then isolated from waste water samples at the facility using the isolated bacterial strains. “However, I was not able to isolate a bacteriophage that could infect the bacteria in the facility.

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